Showing entry for Gamma-butyrobetaine dioxygenase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005167
Protein NameGamma-butyrobetaine dioxygenase
Uniport IdO75936
GeneBBOX1
Gene Id8424
DomainDUF971; TauD
Pfam PF06155   PF02668  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00310 Lysine degradation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045329 carnitine biosynthetic process
molecular function GO:0008336 gamma-butyrobetaine dioxygenase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005506 iron ion binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71262 Carnitine synthesis
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004936 BXGD000295 Mental disorders Mental Disorders
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0796121 BXGD010799 Primrose syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders; Otorhinolaryngologic Diseases; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000764 L-Ascorbic acid 176.12
BXGC0041560 Thiram 239.99
BXGC0044092 Daminozide 160.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein