acompound

Showing entry for Daminozide

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0044092
Compound Name	Daminozide
Structure
Formula	C6H12N2O3
InchiKey	NOQGZXFMHARMLW-UHFFFAOYSA-N
SMILES	CN(N=C(CCC(=O)O)O)C
Inchi	InChI=1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)
IUPAC	4-(2,2-dimethylhydrazinyl)-4-oxobutanoic acid
Molecular Weight	160.08
Pubchem Id	15331
Chembl Id	CHEMBL2164243

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q9NWT6	BXGT021234	Hypoxia-inducible factor 1-alpha inhibitor	reviewed	HIF1AN	-	-	>100000	-	-
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	KDM4A	-	-	-	-	-
Q9UPP1	BXGT021800	Histone lysine demethylase PHF8	reviewed	PHF8	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT022239	Lysine-specific demethylase 2A	reviewed		KDM2A	85000	-	-	-
reviewed	BXGT022239	Lysine-specific demethylase 2A	reviewed		KDM2A	1970	-	-	-
reviewed	BXGT022239	Lysine-specific demethylase 2A	reviewed		KDM2A	-	1500	-	-
reviewed	BXGT005167	Gamma-butyrobetaine dioxygenase	reviewed	Enzyme	BBOX1	-	>100000	-	-
reviewed	BXGT020425	Egl nine homolog 1	reviewed		EGLN1	-	>100000	-	-
reviewed	BXGT021234	Hypoxia-inducible factor 1-alpha inhibitor	reviewed		HIF1AN	-	>100000	-	-
reviewed	BXGT004121	Lysine-specific demethylase 6B	reviewed	Epigenetic regulator	KDM6B	-	>100000	-	-
reviewed	BXGT010239	Lysine-specific demethylase 5C	reviewed		KDM5C	-	>100000	-	-
reviewed	BXGT002006	Lysine-specific demethylase 4E	reviewed		KDM4E	-	>100000	-	-
reviewed	BXGT016629	Lysine-specific demethylase 7A	reviewed		KDM7A	-	2100	-	-
reviewed	BXGT021800	Histone lysine demethylase PHF8	reviewed		PHF8	-	550	-	-
reviewed	BXGT004179	Lysine-specific demethylase 6A	reviewed	Epigenetic regulator	KDM6A	-	>100000	-	-
reviewed	BXGT009338	Lysine-specific demethylase 5A	reviewed		KDM5A	-	2200000	-	-
reviewed	BXGT020465	Lysine-specific demethylase 4C	reviewed		KDM4C	-	2500000	-	-
reviewed	BXGT005104	Lysine-specific demethylase 4A	reviewed		KDM4A	-	>3300000	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	-	KDM4A	IC50	'>'	3300000	nM
O15550	BXGT004179	Lysine-specific demethylase 6A	reviewed	Epigenetic regulator	KDM6A	IC50	'>'	100000	nM
Q9GZT9	BXGT020425	Egl nine homolog 1	reviewed	-	EGLN1	IC50	'>'	100000	nM
P41229	BXGT010239	Lysine-specific demethylase 5C	reviewed	-	KDM5C	IC50	'>'	100000	nM
Q9Y2K7	BXGT022239	Lysine-specific demethylase 2A	reviewed	-	KDM2A	IC50	'='	1500	nM
O15054	BXGT004121	Lysine-specific demethylase 6B	reviewed	Epigenetic regulator	KDM6B	IC50	'>'	100000	nM
Q6ZMT4	BXGT016629	Lysine-specific demethylase 7A	reviewed	-	KDM7A	IC50	'='	2100	nM
Q9UPP1	BXGT021800	Histone lysine demethylase PHF8	reviewed	-	PHF8	IC50	'='	550	nM
Q9Y2K7	BXGT022239	Lysine-specific demethylase 2A	reviewed	-	KDM2A	Ki	'='	85000	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	794	nM
Q9NWT6	BXGT021234	Hypoxia-inducible factor 1-alpha inhibitor	reviewed	-	HIF1AN	IC50	'>'	100000	nM
Q9UPP1	BXGT021800	Histone lysine demethylase PHF8	reviewed	-	PHF8	IC50	'='	19000	nM
O75936	BXGT005167	Gamma-butyrobetaine dioxygenase	reviewed	Enzyme	BBOX1	IC50	'>'	100000	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	IC50	'>'	100000	nM
Q9H3R0	BXGT020465	Lysine-specific demethylase 4C	reviewed	-	KDM4C	IC50	'='	2500000	nM
Q9Y2K7	BXGT022239	Lysine-specific demethylase 2A	reviewed	-	KDM2A	Ki	'='	1970	nM
P29375	BXGT009338	Lysine-specific demethylase 5A	reviewed	-	KDM5A	IC50	'='	2200000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02800	Aria rostellata	Aria rostellata	Others
BXGF03078	Chrysanthemum x morifolium	Chrysanthemum x morifolium	Medicinal Plant
BXGF04964	Chrysanthemum morifolium	Chrysanthemum morifolium	Medicinal Plant
BXGF06284	Panzerina lanata	Panzerina lanata	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}