Showing entry for Poly [ADP-ribose] polymerase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005275
Protein NamePoly [ADP-ribose] polymerase 2
Uniport IdO88554
GeneParp2
Gene Id11546
DomainPARP; PARP_reg; WGR
Pfam PF00644   PF02877   PF05406  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006284 base-excision repair
Biological Process GO:0030592 DNA ADP-ribosylation
Biological Process GO:0006281 DNA repair
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0018312 peptidyl-serine ADP-ribosylation
Biological Process GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
Biological Process GO:0070212 protein poly-ADP-ribosylation
molecular function GO:0003677 DNA binding
molecular function GO:0003950 NAD+ ADP-ribosyltransferase activity
molecular function GO:0140294 NAD DNA ADP-ribosyltransferase activity
molecular function GO:1990404 protein ADP-ribosylase activity
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006125 Nicotinamide 122.12
BXGC0021234 Quinazolinone 146.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein