Showing entry for Gamma-aminobutyric acid receptor-associated protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005353
Protein NameGamma-aminobutyric acid receptor-associated protein
Uniport IdO95166
GeneGABARAP
Gene Id11337
DomainAtg8
Pfam PF02991  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04136 Autophagy - other
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04371 Apelin signaling pathway
5. Organismal Systems 5.1 Immune system hsa04621 NOD-like receptor signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04727 GABAergic synapse
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000045 autophagosome assembly
Biological Process GO:0097352 autophagosome maturation
Biological Process GO:0000422 autophagy of mitochondrion
Biological Process GO:0006995 cellular response to nitrogen starvation
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:0016236 macroautophagy
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0006605 protein targeting
molecular function GO:0048487 beta-tubulin binding
molecular function GO:0050811 GABA receptor binding
molecular function GO:0008017 microtubule binding
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005776 autophagosome
cellular component GO:0000421 autophagosome membrane
cellular component GO:0005930 axoneme
cellular component GO:0044297 cell body
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0000139 Golgi membrane
cellular component GO:0005764 lysosome
cellular component GO:0005874 microtubule
cellular component GO:0005875 microtubule associated complex
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0005790 smooth endoplasmic reticulum
cellular component GO:0097225 sperm midpiece
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-1632852 Macroautophagy
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8854214 TBC/RABGAPs
R-HSA-9007101 Rab regulation of trafficking
R-HSA-9612973 Autophagy
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020071 BXGD001356 Hereditary Sensory Autonomic Neuropathy, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024408 BXGD001768 Machado-Joseph Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027889 BXGD002057 Hereditary Sensory and Autonomic Neuropathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0042769 BXGD002999 Virus Diseases Infections
C0085292 BXGD003153 Stiff-Person Syndrome Immune System Diseases; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206692 BXGD004243 Carcinoma, Lobular Neoplasms; Skin and Connective Tissue Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0278061 BXGD006492 Abnormal mental state Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0429468 BXGD008651 Anovulatory (finding) Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0557874 BXGD009444 Global developmental delay
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0683322 BXGD009782 Mental impairment
C1306341 BXGD012360 Mental handicap
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C4024589 BXGD021330 Aplasia/Hypoplasia of the mandible
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein