Showing entry for Polycystic Ovary Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002355
Disease NamePolycystic Ovary Syndrome
Disease CUI IdC0032460
MeSH Codes C04   C13   C19  
Disease Class NameNeoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id DOID:225  
Disease Ontology Class Namesyndrome
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase 4593 reviewed Kinase
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 5170 reviewed Kinase
O43323 BXGT004587 Desert hedgehog protein 50846 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43765 BXGT004621 Small glutamine-rich tetratricopeptide repeat-containing protein alpha 6449 reviewed
O43826 BXGT004629 Glucose-6-phosphate exchanger SLC37A4 2542 reviewed Transporter
O60240 BXGT004860 Perilipin-1 5346 reviewed
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60658 BXGT004890 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 5151 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75362 BXGT005114 Zinc finger protein 217 7764 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95166 BXGT005353 Gamma-aminobutyric acid receptor-associated protein 11337 reviewed Cellular structure
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
O96020 BXGT005416 G1/S-specific cyclin-E2 9134 reviewed Enzyme modulator
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00709 BXGT005621 Alpha-lactalbumin 3906 reviewed
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01215 BXGT005743 Glycoprotein hormones alpha chain 1081 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02679 BXGT005918 Fibrinogen gamma chain 2266 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial 506 reviewed Transporter
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07148 BXGT006559 Fatty acid-binding protein, liver 2168 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07948 BXGT006702 Tyrosine-protein kinase Lyn 4067 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08476 BXGT006774 Inhibin beta A chain 3624 reviewed Signaling
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08574 BXGT006792 Cytochrome c1, heme protein, mitochondrial 1537 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P08779 BXGT006824 Keratin, type I cytoskeletal 16 3868 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14061 BXGT007979 Estradiol 17-beta-dehydrogenase 1 3292 reviewed Enzyme
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15085 BXGT008077 Carboxypeptidase A1 1357 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P16471 BXGT008233 Prolactin receptor 5618 reviewed Signaling
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6715 reviewed Enzyme
P18505 BXGT008409 Gamma-aminobutyric acid receptor subunit beta-1 2560 reviewed Ion channel
P18846 BXGT008430 Cyclic AMP-dependent transcription factor ATF-1 466 reviewed
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P20702 BXGT008592 Integrin alpha-X 3687 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21333 BXGT008638 Filamin-A 2316 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21583 BXGT008667 Kit ligand 4254 reviewed
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 6198 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P23945 BXGT008931 Follicle-stimulating hormone receptor 2492 reviewed G-protein coupled receptor
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25100 BXGT009017 Alpha-1D adrenergic receptor 146 reviewed G-protein coupled receptor
P25105 BXGT009021 Platelet-activating factor receptor 5724 reviewed G-protein coupled receptor
P25311 BXGT009036 Zinc-alpha-2-glycoprotein 563 reviewed
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P25815 BXGT009074 Protein S100-P 6286 reviewed Calcium-binding protein
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27037 BXGT009153 Activin receptor type-2A 92 reviewed Kinase
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29376 BXGT009339 Leukocyte tyrosine kinase receptor 4058 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31323 BXGT009521 cAMP-dependent protein kinase type II-beta regulatory subunit 5577 reviewed
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P33981 BXGT009744 Dual specificity protein kinase TTK 7272 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35368 BXGT009822 Alpha-1B adrenergic receptor 147 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A 657 reviewed Kinase
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37059 BXGT009957 Estradiol 17-beta-dehydrogenase 2 3294 reviewed Enzyme
P37088 BXGT009961 Amiloride-sensitive sodium channel subunit alpha 6337 reviewed Ion channel
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40261 BXGT010170 Nicotinamide N-methyltransferase 4837 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40967 BXGT010212 Melanocyte protein PMEL 6490 reviewed Signaling
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P41252 BXGT010245 Isoleucine--tRNA ligase, cytoplasmic 3376 reviewed Enzyme
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P41968 BXGT010275 Melanocortin receptor 3 4159 reviewed G-protein coupled receptor
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43115 BXGT010356 Prostaglandin E2 receptor EP3 subtype 5733 reviewed G-protein coupled receptor
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P47895 BXGT010593 Aldehyde dehydrogenase family 1 member A3 220 reviewed Enzyme
P48039 BXGT010607 Melatonin receptor type 1A 4543 reviewed G-protein coupled receptor
P48060 BXGT010615 Glioma pathogenesis-related protein 1 11010 reviewed Immune response
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P50479 BXGT010804 PDZ and LIM domain protein 4 8572 reviewed Cellular structure
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51451 BXGT010848 Tyrosine-protein kinase Blk 640 reviewed Kinase
P51687 BXGT010882 Sulfite oxidase, mitochondrial 6821 reviewed
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P51884 BXGT010903 Lumican 4060 reviewed
P52895 BXGT010961 Aldo-keto reductase family 1 member C2 1646 reviewed Enzyme
P53041 BXGT010968 Serine/threonine-protein phosphatase 5 5536 reviewed
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P55210 BXGT011110 Caspase-7 840 reviewed Enzyme
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P56937 BXGT011205 3-keto-steroid reductase 51478 reviewed
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61019 BXGT011348 Ras-related protein Rab-2A 5862 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P78352 BXGT011836 Disks large homolog 4 1742 reviewed Receptor
P78563 BXGT011850 Double-stranded RNA-specific editase 1 104 reviewed Enzyme
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
P82279 BXGT011972 Protein crumbs homolog 1 23418 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q03405 BXGT012713 Urokinase plasminogen activator surface receptor 5329 reviewed
Q04771 BXGT012783 Activin receptor type-1 90 reviewed Kinase
Q04828 BXGT012787 Aldo-keto reductase family 1 member C1 1645 reviewed Enzyme
Q05516 BXGT012822 Zinc finger and BTB domain-containing protein 16 7704 reviewed Transcription factor
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06520 BXGT012880 Bile salt sulfotransferase 6822 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK 3702 reviewed Kinase
Q11130 BXGT013216 Alpha-(1,3)-fucosyltransferase 7 2529 reviewed Enzyme
Q12772 BXGT013262 Sterol regulatory element-binding protein 2 6721 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13219 BXGT013327 Pappalysin-1 5069 reviewed
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13257 BXGT013333 Mitotic spindle assembly checkpoint protein MAD2A 4085 reviewed
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13370 BXGT013345 cGMP-inhibited 3',5'-cyclic phosphodiesterase B 5140 reviewed
Q13464 BXGT013357 Rho-associated protein kinase 1 6093 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta 817 reviewed Kinase
Q13705 BXGT013393 Activin receptor type-2B 93 reviewed Kinase
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q14032 BXGT013438 Bile acid-CoA:amino acid N-acyltransferase 570 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q14576 BXGT013487 ELAV-like protein 3 1995 reviewed
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15375 BXGT013562 Ephrin type-A receptor 7 2045 reviewed Kinase
Q15562 BXGT013579 Transcriptional enhancer factor TEF-4 8463 reviewed Transcription factor
Q15750 BXGT013592 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 10454 reviewed Kinase
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16548 BXGT013636 Bcl-2-related protein A1 597 reviewed Signaling
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16850 BXGT013681 Lanosterol 14-alpha demethylase 1595 reviewed Enzyme
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q2M1P5 BXGT014129 Kinesin-like protein KIF7 374654 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q53EZ4 BXGT015010 Centrosomal protein of 55 kDa 55165 reviewed
Q6NUJ5 BXGT016428 PWWP domain-containing protein 2B 170394 reviewed
Q6UWP2 BXGT016567 Dehydrogenase/reductase SDR family member 11 79154 reviewed Enzyme
Q6VVX0 BXGT016585 Vitamin D 25-hydroxylase 120227 reviewed
Q6ZMJ4 BXGT016628 Interleukin-34 146433 reviewed
Q6ZN16 BXGT016630 Mitogen-activated protein kinase kinase kinase 15 389840 reviewed
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q86SG5 BXGT017599 Protein S100-A7A 338324 reviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q86VL8 BXGT017618 Multidrug and toxin extrusion protein 2 146802 reviewed Transporter
Q8N4E7 BXGT018511 Ferritin, mitochondrial 94033 reviewed Storage
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8WWA0 BXGT018999 Intelectin-1 55600 reviewed
Q8WWY3 BXGT019006 U4/U6 small nuclear ribonucleoprotein Prp31 26121 reviewed Nucleic acid binding
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q93088 BXGT019458 Betaine--homocysteine S-methyltransferase 1 635 reviewed
Q969S2 BXGT019612 Endonuclease 8-like 2 252969 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96BR1 BXGT019627 Serine/threonine-protein kinase Sgk3 23678 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase 55872 reviewed Kinase
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BX66 BXGT020158 Sorbin and SH3 domain-containing protein 1 10580 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 25865 reviewed Kinase
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H0H5 BXGT020436 Rac GTPase-activating protein 1 29127 reviewed Enzyme modulator
Q9H1D0 BXGT020445 Transient receptor potential cation channel subfamily V member 6 55503 reviewed Ion channel
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NPF5 BXGT021154 DNA methyltransferase 1-associated protein 1 55929 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 51765 reviewed Kinase
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UGB7 BXGT021678 Inositol oxygenase 55586 reviewed Enzyme
Q9UGI9 BXGT021682 5'-AMP-activated protein kinase subunit gamma-3 53632 reviewed Enzyme modulator
Q9UHF0 BXGT021699 Tachykinin-3 6866 reviewed
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9UKA9 BXGT021740 Polypyrimidine tract-binding protein 2 58155 reviewed
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UPT6 BXGT021801 C-Jun-amino-terminal kinase-interacting protein 3 23162 reviewed Enzyme modulator
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
Q9Y6R4 BXGT022340 Mitogen-activated protein kinase kinase kinase 4 4216 reviewed Kinase
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P35232 BXGT022663 Prohibitin 5245 reviewed
P24462 BXGT022674 Cytochrome P450 3A7 1551 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UKG1 BXGT022975 DCC-interacting protein 13-alpha 26060 reviewed
Q92878 BXGT023071 DNA repair protein RAD50 10111 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
O14520 BXGT024716 Aquaporin-7 364 reviewed Ion channel
P38646 BXGT024954 Stress-70 protein, mitochondrial 3313 reviewed
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P53621 BXGT025196 Coatomer subunit alpha 1314 reviewed Transporter
Q9Y6M1 BXGT025468 Insulin-like growth factor 2 mRNA-binding protein 2 10644 reviewed Enzyme
Q7Z3B1 BXGT025707 Neuronal growth regulator 1 257194 reviewed
P84095 BXGT025743 Rho-related GTP-binding protein RhoG 391 reviewed Enzyme modulator
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
Q8NI99 BXGT025986 Angiopoietin-related protein 6 83854 reviewed Signaling
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease