Showing entry for Adenylate kinase isoenzyme 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005583
Protein NameAdenylate kinase isoenzyme 1
Uniport IdP00568
GeneAK1
Gene Id203
DomainADK
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00730 Thiamine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006172 ADP biosynthetic process
Biological Process GO:0046033 AMP metabolic process
Biological Process GO:0046034 ATP metabolic process
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0006165 nucleoside diphosphate phosphorylation
Biological Process GO:0009142 nucleoside triphosphate biosynthetic process
Biological Process GO:0006163 purine nucleotide metabolic process
molecular function GO:0004017 adenylate kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0004550 nucleoside diphosphate kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0022602 BXGD001564 Actinic keratosis Neoplasms; Skin and Connective Tissue Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027341 BXGD001982 Nail-Patella Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0036329 BXGD002596 Schistosomiasis japonica Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0398564 BXGD008193 Deficiency of adenylate kinase
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751958 BXGD010654 Lymphoma, Lymphocytic, Intermediate Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0872084 BXGD011319 Sarcopenia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1318711 BXGD012405 Herpes simplex type 1 infection Infections; Skin and Connective Tissue Diseases
C1387532 BXGD012957 Chronic hemolytic anemia Hemic and Lymphatic Diseases
C2675459 BXGD017289 Adenylate Kinase Deficiency, Hemolytic Anemia Due To Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3278252 BXGD018734 Red cell adenylate kinase deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein