Showing entry for Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007144
Disease NameMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse
Disease CUI IdC0334634
MeSH Codes C04   C20   C15  
Disease Class NameNeoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14744 BXGT004089 Protein arginine N-methyltransferase 5 10419 reviewed Epigenetic regulator
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O43246 BXGT004577 Cationic amino acid transporter 4 6545 reviewed Transporter
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75604 BXGT005139 Ubiquitin carboxyl-terminal hydrolase 2 9099 reviewed Enzyme
P00568 BXGT005583 Adenylate kinase isoenzyme 1 203 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04083 BXGT006147 Annexin A1 301 reviewed
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P06239 BXGT006427 Tyrosine-protein kinase Lck 3932 reviewed Kinase
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27707 BXGT009201 Deoxycytidine kinase 1633 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30281 BXGT009416 G1/S-specific cyclin-D3 896 reviewed Enzyme modulator
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50613 BXGT010815 Cyclin-dependent kinase 7 1022 reviewed Kinase
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78344 BXGT011835 Eukaryotic translation initiation factor 4 gamma 2 1982 reviewed Nucleic acid binding
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q06828 BXGT012893 Fibromodulin 2331 reviewed
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13370 BXGT013345 cGMP-inhibited 3',5'-cyclic phosphodiesterase B 5140 reviewed
Q13489 BXGT013364 Baculoviral IAP repeat-containing protein 3 330 reviewed Enzyme modulator
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15843 BXGT013608 NEDD8 4738 reviewed Nucleic acid binding
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q53H47 BXGT015014 Histone-lysine N-methyltransferase SETMAR 6419 reviewed Epigenetic regulator
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha 8476 reviewed Kinase
Q6GTX8 BXGT016315 Leukocyte-associated immunoglobulin-like receptor 1 3903 reviewed Receptor
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase 55872 reviewed Kinase
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q9BU89 BXGT020132 Deoxyhypusine hydroxylase 83475 reviewed
Q9BX66 BXGT020158 Sorbin and SH3 domain-containing protein 1 10580 reviewed
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9NP56 BXGT021142 cAMP-specific 3',5'-cyclic phosphodiesterase 7B 27115 reviewed
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 11040 reviewed Kinase
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UDY8 BXGT021670 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 10892 reviewed Enzyme
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UIQ6 BXGT021721 Leucyl-cystinyl aminopeptidase 4012 reviewed Enzyme
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9ULW0 BXGT021766 Targeting protein for Xklp2 22974 reviewed Cellular structure
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P56703 BXGT023722 Proto-oncogene Wnt-3 7473 reviewed Signaling
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q7Z6A9 BXGT025024 B- and T-lymphocyte attenuator 151888 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease