Showing entry for Neprilysin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006690
Protein NameNeprilysin
Uniport IdP07861
GeneMme
Gene Id24590
DomainPeptidase_M13; Peptidase_M13_N
Pfam PF01431   PF05649  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:0150094 amyloid-beta clearance by cellular catabolic process
Biological Process GO:0050435 amyloid-beta metabolic process
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0071492 cellular response to UV-A
Biological Process GO:0071493 cellular response to UV-B
Biological Process GO:0046449 creatinine metabolic process
Biological Process GO:0001822 kidney development
Biological Process GO:0007611 learning or memory
Biological Process GO:0030324 lung development
Biological Process GO:0061837 neuropeptide processing
Biological Process GO:0006518 peptide metabolic process
Biological Process GO:0001890 placenta development
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:0006508 proteolysis
Biological Process GO:0090399 replicative senescence
Biological Process GO:0019233 sensory perception of pain
molecular function GO:1901612 cardiolipin binding
molecular function GO:0004175 endopeptidase activity
molecular function GO:0008238 exopeptidase activity
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0070012 oligopeptidase activity
molecular function GO:0008233 peptidase activity
molecular function GO:0042277 peptide binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0030424 axon
cellular component GO:0005903 brush border
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0030425 dendrite
cellular component GO:0005769 early endosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0043025 neuronal cell body
cellular component GO:0044306 neuron projection terminus
cellular component GO:0005886 plasma membrane
cellular component GO:0098793 presynapse
cellular component GO:0045202 synapse
cellular component GO:0008021 synaptic vesicle
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000314 Isorhamnetin 316.26
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein