Showing entry for Glutathione S-transferase A2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006868
Protein NameGlutathione S-transferase A2
Uniport IdP09210
GeneGSTA2
Gene Id2939
DomainGST_C_3; GST_N
Pfam PF14497   PF02798  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.6 Metabolism of other amino acids hsa00480 Glutathione metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01524 Platinum drug resistance
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
6. Human Diseases 6.2 Cancers: Specific types hsa05225 Hepatocellular carcinoma
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030855 epithelial cell differentiation
Biological Process GO:1901687 glutathione derivative biosynthetic process
Biological Process GO:0006749 glutathione metabolic process
Biological Process GO:0035722 interleukin-12-mediated signaling pathway
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0004364 glutathione transferase activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156590 Glutathione conjugation
R-HSA-168256 Immune System
R-HSA-211859 Biological oxidations
R-HSA-447115 Interleukin-12 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-9020591 Interleukin-12 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001948 BXGD000091 Alcohol consumption Behavior and Behavior Mechanisms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0427460 BXGD008616 Red cell distribution width determination
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
BXGC0017757 Androstenedione 286.19
BXGC0046518 Chloroquine 319.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein