Showing entry for Malignant Head and Neck Neoplasm


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006621
Disease NameMalignant Head and Neck Neoplasm
Disease CUI IdC0278996
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0002664  
Human Phenotype Ontology TermNeoplasm
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00139 BXGT003881 Kinesin-like protein KIF2A 3796 reviewed Cellular structure
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14744 BXGT004089 Protein arginine N-methyltransferase 5 10419 reviewed Epigenetic regulator
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha 1147 reviewed Kinase
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15296 BXGT004148 Arachidonate 15-lipoxygenase B 247 reviewed Enzyme
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43283 BXGT004583 Mitogen-activated protein kinase kinase kinase 13 9175 reviewed Kinase
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43603 BXGT004604 Galanin receptor type 2 8811 reviewed G-protein coupled receptor
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60285 BXGT004867 NUAK family SNF1-like kinase 1 9891 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94762 BXGT005329 ATP-dependent DNA helicase Q5 9400 reviewed Enzyme
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09210 BXGT006868 Glutathione S-transferase A2 2939 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09238 BXGT006875 Stromelysin-2 4319 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0CG48 BXGT007468 Polyubiquitin-C 7316 reviewed Nucleic acid binding
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14625 BXGT008029 Endoplasmin 7184 reviewed Chaperone
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18440 BXGT008404 Arylamine N-acetyltransferase 1 9 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 54578 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22460 BXGT008774 Potassium voltage-gated channel subfamily A member 5 3741 reviewed Ion channel
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23921 BXGT008927 Ribonucleoside-diphosphate reductase large subunit 6240 reviewed Enzyme
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P24593 BXGT008979 Insulin-like growth factor-binding protein 5 3488 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25786 BXGT009068 Proteasome subunit alpha type-1 5682 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29034 BXGT009309 Protein S100-A2 6273 reviewed Calcium-binding protein
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 1136 reviewed Ion channel
P32926 BXGT009680 Desmoglein-3 1830 reviewed Cell adhesion
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34059 BXGT009749 N-acetylgalactosamine-6-sulfatase 2588 reviewed Enzyme
P34896 BXGT009767 Serine hydroxymethyltransferase, cytosolic 6470 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35408 BXGT009828 Prostaglandin E2 receptor EP4 subtype 5734 reviewed G-protein coupled receptor
P35579 BXGT009852 Myosin-9 4627 reviewed
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40199 BXGT010166 Carcinoembryonic antigen-related cell adhesion molecule 6 4680 reviewed
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40394 BXGT010178 Alcohol dehydrogenase class 4 mu/sigma chain 131 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P43351 BXGT010380 DNA repair protein RAD52 homolog 5893 reviewed Nucleic acid binding
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46781 BXGT010539 40S ribosomal protein S9 6203 reviewed Nucleic acid binding
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46940 BXGT010556 Ras GTPase-activating-like protein IQGAP1 8826 reviewed Enzyme modulator
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49137 BXGT010680 MAP kinase-activated protein kinase 2 9261 reviewed Kinase
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P49959 BXGT010766 Double-strand break repair protein MRE11 4361 reviewed
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51531 BXGT010851 Probable global transcription activator SNF2L2 6595 reviewed Epigenetic regulator
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P53778 BXGT011013 Mitogen-activated protein kinase 12 6300 reviewed Kinase
P54136 BXGT011033 Arginine--tRNA ligase, cytoplasmic 5917 reviewed
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P54803 BXGT011082 Galactocerebrosidase 2581 reviewed
P55055 BXGT011101 Oxysterols receptor LXR-beta 7376 reviewed Nuclear receptor
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P57735 BXGT011214 Ras-related protein Rab-25 57111 reviewed
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62330 BXGT011423 ADP-ribosylation factor 6 382 reviewed
P62979 BXGT011476 Ubiquitin-40S ribosomal protein S27a 6233 reviewed Nucleic acid binding
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P68400 BXGT011599 Casein kinase II subunit alpha 1457 reviewed Kinase
P78504 BXGT011844 Protein jagged-1 182 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01831 BXGT012621 DNA repair protein complementing XP-C cells 7508 reviewed Nucleic acid binding
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03405 BXGT012713 Urokinase plasminogen activator surface receptor 5329 reviewed
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q08188 BXGT012965 Protein-glutamine gamma-glutamyltransferase E 7053 reviewed Enzyme
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q10589 BXGT013203 Bone marrow stromal antigen 2 684 reviewed
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q12923 BXGT013281 Tyrosine-protein phosphatase non-receptor type 13 5783 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 5062 reviewed Kinase
Q13283 BXGT013334 Ras GTPase-activating protein-binding protein 1 10146 reviewed Nucleic acid binding
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13489 BXGT013364 Baculoviral IAP repeat-containing protein 3 330 reviewed Enzyme modulator
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14527 BXGT013479 Helicase-like transcription factor 6596 reviewed
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase 9833 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14973 BXGT013515 Sodium/bile acid cotransporter 6554 reviewed Transporter
Q15047 BXGT013528 Histone-lysine N-methyltransferase SETDB1 9869 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15119 BXGT013541 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 5164 reviewed Kinase
Q15554 BXGT013577 Telomeric repeat-binding factor 2 7014 reviewed
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15843 BXGT013608 NEDD8 4738 reviewed Nucleic acid binding
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16513 BXGT013632 Serine/threonine-protein kinase N2 5586 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16647 BXGT013648 Prostacyclin synthase 5740 reviewed
Q16659 BXGT013652 Mitogen-activated protein kinase 6 5597 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q16696 BXGT013658 Cytochrome P450 2A13 1553 reviewed
Q16739 BXGT013663 Ceramide glucosyltransferase 7357 reviewed Enzyme
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6VVX0 BXGT016585 Vitamin D 25-hydroxylase 120227 reviewed
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q86VP1 BXGT017619 Tax1-binding protein 1 8887 reviewed
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8IYD8 BXGT018367 Fanconi anemia group M protein 57697 reviewed Enzyme
Q8TCG1 BXGT018797 Protein CIP2A 57650 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8WWM9 BXGT019001 Cytoglobin 114757 reviewed
Q8WYH8 BXGT019019 Inhibitor of growth protein 5 84289 reviewed Nucleic acid binding
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92854 BXGT019385 Semaphorin-4D 10507 reviewed Signaling
Q92905 BXGT019393 COP9 signalosome complex subunit 5 10987 reviewed Enzyme
Q969Q1 BXGT019610 E3 ubiquitin-protein ligase TRIM63 84676 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q96JA1 BXGT019681 Leucine-rich repeats and immunoglobulin-like domains protein 1 26018 reviewed Receptor
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99704 BXGT019950 Docking protein 1 1796 reviewed
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q99873 BXGT019972 Protein arginine N-methyltransferase 1 3276 reviewed Epigenetic regulator
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9BZ95 BXGT020196 Histone-lysine N-methyltransferase NSD3 54904 reviewed Epigenetic regulator
Q9H4B4 BXGT020474 Serine/threonine-protein kinase PLK3 1263 reviewed Kinase
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9HBH1 BXGT020519 Peptide deformylase, mitochondrial 64146 reviewed
Q9NPI8 BXGT021161 Fanconi anemia group F protein 2188 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NR97 BXGT021182 Toll-like receptor 8 51311 reviewed
Q9NW38 BXGT021230 E3 ubiquitin-protein ligase FANCL 55120 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 51079 reviewed Enzyme
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9UGL1 BXGT021685 Lysine-specific demethylase 5B 10765 reviewed Epigenetic regulator
Q9UH17 BXGT021691 DNA dC->dU-editing enzyme APOBEC-3B 9582 reviewed Enzyme
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UJT0 BXGT021728 Tubulin epsilon chain 51175 reviewed Cellular structure
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UNL4 BXGT021790 Inhibitor of growth protein 4 51147 reviewed Nucleic acid binding
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9UQ84 BXGT021807 Exonuclease 1 9156 reviewed Enzyme
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y5W5 BXGT022303 Wnt inhibitory factor 1 11197 reviewed Calcium-binding protein
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q6PI26 BXGT022773 Protein SHQ1 homolog 55164 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q92878 BXGT023071 DNA repair protein RAD50 10111 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q9NZM1 BXGT023948 Myoferlin 26509 reviewed Transporter
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q13686 BXGT024292 Nucleic acid dioxygenase ALKBH1 8846 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
Q9Y6M1 BXGT025468 Insulin-like growth factor 2 mRNA-binding protein 2 10644 reviewed Enzyme
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
Q5BJF2 BXGT026107 Sigma intracellular receptor 2 27346 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease