Showing entry for Glycogen phosphorylase, brain form



                       
General Target Information
BXGT IdBXGT007673
Protein NameGlycogen phosphorylase, brain form
Uniport IdP11216
GenePYGB
Gene Id5834
DomainPhosphorylase
Pfam PF00343  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0005980 glycogen catabolic process
Biological Process GO:0043312 neutrophil degranulation
molecular function GO:0008184 glycogen phosphorylase activity
molecular function GO:0102250 linear malto-oligosaccharide phosphorylase activity
molecular function GO:0030170 pyridoxal phosphate binding
molecular function GO:0102499 SHG alpha-glucan phosphorylase activity
cellular component GO:0035578 azurophil granule lumen
cellular component GO:0005737 cytoplasm
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-71387 Metabolism of carbohydrates
R-HSA-8982491 Glycogen metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0036095 BXGD002576 Salivary Gland Neoplasms Neoplasms; Stomatognathic Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0220636 BXGD004304 Malignant neoplasm of salivary gland Neoplasms; Stomatognathic Diseases
C0349588 BXGD007933 Short stature
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0020188 methyl-galactopyranoside 194.08
BXGC0024261 Adenosine Phosphate 347.06
BXGC0038766 Glucose 180.06
BXGC0040187 methylglucoside 194.08
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0043088 Pyridoxal Phosphate 247.02
BXGC0043971 methylglucoside 194.08
BXGC0047692 Gefitinib 446.15
BXGC0052400 Melibiose 342.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein