Showing entry for Picropodophyllotoxin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0042376
Compound NamePicropodophyllotoxin
Structure
FormulaC22H22O8
InchiKeyYJGVMLPVUAXIQN-HAEOHBJNSA-N
SMILESCOc1cc(cc(c1OC)OC)[C@H]1[C@@H]2C(=O)OC[C@@H]2[C@H](c2c1cc1OCOc1c2)O
InchiInChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19+,20-/m0/s1
IUPAC(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Molecular Weight414.13
Pubchem Id72435
Chembl IdCHEMBL283120
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL283120
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 25 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 9200 nM
O00311 BXGT003908 Cell division cycle 7-related protein kinase reviewed Kinase CDC7 Kd apparent '>' 30000 nM
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Kd apparent '>' 30000 nM
Q13705 BXGT013393 Activin receptor type-2B reviewed Kinase ACVR2B Kd apparent '>' 30000 nM
P22612 BXGT008785 cAMP-dependent protein kinase catalytic subunit gamma reviewed Kinase PRKACG Kd apparent '>' 30000 nM
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Kd apparent '>' 30000 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 79432 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 100000 nM
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 3162 nM
P07741 BXGT006666 Adenine phosphoribosyltransferase reviewed - APRT Kd apparent '>' 30000 nM
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Kd apparent '>' 30000 nM
Q9NSY1 BXGT021209 BMP-2-inducible protein kinase reviewed Kinase BMP2K Kd apparent '>' 30000 nM
P54753 BXGT011073 Ephrin type-B receptor 3 reviewed Kinase EPHB3 Kd apparent '>' 30000 nM
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Kd apparent '>' 30000 nM
P11216 BXGT007673 Glycogen phosphorylase, brain form reviewed Enzyme PYGB Kd apparent '>' 30000 nM
Q86XP3 BXGT017630 ATP-dependent RNA helicase DDX42 reviewed - DDX42 Kd apparent '>' 30000 nM
Q16513 BXGT013632 Serine/threonine-protein kinase N2 reviewed Kinase PKN2 Kd apparent '>' 30000 nM
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Kd apparent '>' 30000 nM
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Kd apparent '>' 30000 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 Kd apparent '>' 30000 nM
P22830 BXGT008809 Ferrochelatase, mitochondrial reviewed Enzyme FECH Kd apparent '>' 30000 nM
P33991 BXGT009745 DNA replication licensing factor MCM4 reviewed Enzyme MCM4 Kd apparent '>' 30000 nM
Q12851 BXGT013271 Mitogen-activated protein kinase kinase kinase kinase 2 reviewed Kinase MAP4K2 Kd apparent '>' 30000 nM
Q99759 BXGT019960 Mitogen-activated protein kinase kinase kinase 3 reviewed Kinase MAP3K3 Kd apparent '>' 30000 nM
Q9H093 BXGT020433 NUAK family SNF1-like kinase 2 reviewed Kinase NUAK2 Kd apparent '>' 30000 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Kd apparent '>' 30000 nM
Q9Y4K4 BXGT022282 Mitogen-activated protein kinase kinase kinase kinase 5 reviewed Kinase MAP4K5 Kd apparent '>' 30000 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Kd apparent '>' 30000 nM
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK Kd apparent '>' 30000 nM
P53667 BXGT011008 LIM domain kinase 1 reviewed Kinase LIMK1 Kd apparent '>' 30000 nM
P04629 BXGT006239 High affinity nerve growth factor receptor reviewed Kinase NTRK1 Kd apparent '>' 30000 nM
O15197 BXGT004136 Ephrin type-B receptor 6 reviewed Kinase EPHB6 Kd apparent '>' 30000 nM
Q58FF8 BXGT015229 Putative heat shock protein HSP 90-beta 2 reviewed - HSP90AB2P Kd apparent '>' 30000 nM
P49840 BXGT010749 Glycogen synthase kinase-3 alpha reviewed Kinase GSK3A Kd apparent '>' 30000 nM
P07948 BXGT006702 Tyrosine-protein kinase Lyn reviewed Kinase LYN Kd apparent '>' 30000 nM
Q9Y5S2 BXGT022301 Serine/threonine-protein kinase MRCK beta reviewed Kinase CDC42BPB Kd apparent '>' 30000 nM
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 reviewed Kinase MAP4K4 Kd apparent '>' 30000 nM
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 reviewed Kinase IRAK1 Kd apparent '>' 30000 nM
O14976 BXGT004118 Cyclin-G-associated kinase reviewed Kinase GAK Kd apparent '>' 30000 nM
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Kd apparent '>' 30000 nM
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 reviewed Enzyme ACOX1 Kd apparent '>' 30000 nM
Q9Y616 BXGT022313 Interleukin-1 receptor-associated kinase 3 reviewed Kinase IRAK3 Kd apparent '>' 30000 nM
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Kd apparent '>' 30000 nM
P31689 BXGT009569 DnaJ homolog subfamily A member 1 reviewed - DNAJA1 Kd apparent '>' 30000 nM
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Kd apparent '>' 30000 nM
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Kd apparent '>' 30000 nM
Q13163 BXGT013321 Dual specificity mitogen-activated protein kinase kinase 5 reviewed Kinase MAP2K5 Kd apparent '>' 30000 nM
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Kd apparent '>' 30000 nM
Q8NI60 BXGT018572 Atypical kinase COQ8A, mitochondrial reviewed Kinase COQ8A Kd apparent '>' 30000 nM
P08574 BXGT006792 Cytochrome c1, heme protein, mitochondrial reviewed - CYC1 Kd apparent '>' 30000 nM
Q9BZE4 BXGT020197 Nucleolar GTP-binding protein 1 reviewed - GTPBP4 Kd apparent '>' 30000 nM
P51956 BXGT010909 Serine/threonine-protein kinase Nek3 reviewed Kinase NEK3 Kd apparent '>' 30000 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 27 %
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Kd apparent '>' 30000 nM
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta reviewed Kinase PTK2B Kd apparent '>' 30000 nM
Q8TD08 BXGT018803 Mitogen-activated protein kinase 15 reviewed Kinase MAPK15 Kd apparent '>' 30000 nM
Q00537 BXGT012536 Cyclin-dependent kinase 17 reviewed Kinase CDK17 Kd apparent '>' 30000 nM
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Kd apparent '>' 30000 nM
Q13976 BXGT013409 cGMP-dependent protein kinase 1 reviewed Kinase PRKG1 Kd apparent '>' 30000 nM
P05141 BXGT006325 ADP/ATP translocase 2 reviewed Transporter SLC25A5 Kd apparent '>' 30000 nM
Q7RTN6 BXGT017085 STE20-related kinase adapter protein alpha reviewed Kinase STRADA Kd apparent '>' 30000 nM
P41250 BXGT010244 Glycine--tRNA ligase reviewed Enzyme GARS1 Kd apparent '>' 30000 nM
Q9NSE4 BXGT021207 Isoleucine--tRNA ligase, mitochondrial reviewed Enzyme IARS2 Kd apparent '>' 30000 nM
P26196 BXGT009089 Probable ATP-dependent RNA helicase DDX6 reviewed - DDX6 Kd apparent '>' 30000 nM
P11274 BXGT007681 Breakpoint cluster region protein reviewed Enzyme modulator BCR Kd apparent '>' 30000 nM
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 reviewed Kinase CHEK1 Kd apparent '>' 30000 nM
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Kd apparent '>' 30000 nM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Kd apparent '>' 30000 nM
Q15569 BXGT013580 Dual specificity testis-specific protein kinase 1 reviewed Kinase TESK1 Kd apparent '>' 30000 nM
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI Kd apparent '>' 30000 nM
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A reviewed - SMC1A Kd apparent '>' 30000 nM
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 reviewed Kinase BMPR2 Kd apparent '>' 30000 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Kd apparent '>' 30000 nM
Q13470 BXGT013359 Non-receptor tyrosine-protein kinase TNK1 reviewed Kinase TNK1 Kd apparent '>' 30000 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' -2 %
P49589 BXGT010714 Cysteine--tRNA ligase, cytoplasmic reviewed Enzyme CARS1 Kd apparent '>' 30000 nM
Q9H773 BXGT020489 dCTP pyrophosphatase 1 reviewed - DCTPP1 Kd apparent '>' 30000 nM
P49748 BXGT010733 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial reviewed Enzyme ACADVL Kd apparent '>' 30000 nM
P33981 BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK Kd apparent '>' 30000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 70 nM
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Kd apparent '>' 30000 nM
Q86TW2 BXGT017609 Uncharacterized aarF domain-containing protein kinase 1 reviewed Kinase ADCK1 Kd apparent '>' 30000 nM
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Kd apparent '>' 30000 nM
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 reviewed Kinase SIK3 Kd apparent '>' 30000 nM
P20340 BXGT008566 Ras-related protein Rab-6A reviewed - RAB6A Kd apparent '>' 30000 nM
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Kd apparent '>' 30000 nM
P48426 BXGT010630 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha reviewed Kinase PIP4K2A Kd apparent '>' 30000 nM
P07947 BXGT006701 Tyrosine-protein kinase Yes reviewed Kinase YES1 Kd apparent '>' 30000 nM
P15056 BXGT008075 Serine/threonine-protein kinase B-raf reviewed Kinase BRAF Kd apparent '>' 30000 nM
Q2M2I8 BXGT014130 AP2-associated protein kinase 1 reviewed Kinase AAK1 Kd apparent '>' 30000 nM
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 reviewed Kinase STK11 Kd apparent '>' 30000 nM
O00238 BXGT003900 Bone morphogenetic protein receptor type-1B reviewed Kinase BMPR1B Kd apparent '>' 30000 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Kd apparent '>' 30000 nM
Q16832 BXGT013678 Discoidin domain-containing receptor 2 reviewed Kinase DDR2 Kd apparent '>' 30000 nM
P08240 BXGT006754 Signal recognition particle receptor subunit alpha reviewed Nucleic acid binding SRPRA Kd apparent '>' 30000 nM
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase reviewed Kinase AKT3 Kd apparent '>' 30000 nM
Q9NYV4 BXGT021262 Cyclin-dependent kinase 12 reviewed Kinase CDK12 Kd apparent '>' 30000 nM
O75643 BXGT005142 U5 small nuclear ribonucleoprotein 200 kDa helicase reviewed - SNRNP200 Kd apparent '>' 30000 nM
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Kd apparent '>' 30000 nM
Q04771 BXGT012783 Activin receptor type-1 reviewed Kinase ACVR1 Kd apparent '>' 30000 nM
Q00536 BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 Kd apparent '>' 30000 nM
Q9UHD8 BXGT021698 Septin-9 reviewed Enzyme modulator SEPTIN9 Kd apparent '>' 30000 nM
Q14164 BXGT013451 Inhibitor of nuclear factor kappa-B kinase subunit epsilon reviewed Kinase IKBKE Kd apparent '>' 30000 nM
Q9H0A0 BXGT020434 RNA cytidine acetyltransferase reviewed - NAT10 Kd apparent '>' 30000 nM
Q32MK0 BXGT014323 Myosin light chain kinase 3 reviewed Kinase MYLK3 Kd apparent '>' 30000 nM
Q16512 BXGT013631 Serine/threonine-protein kinase N1 reviewed Kinase PKN1 Kd apparent '>' 30000 nM
Q9H2K8 BXGT020455 Serine/threonine-protein kinase TAO3 reviewed Kinase TAOK3 Kd apparent '>' 30000 nM
Q9UBE8 BXGT021652 Serine/threonine-protein kinase NLK reviewed Kinase NLK Kd apparent '>' 30000 nM
Q6PHR2 BXGT016467 Serine/threonine-protein kinase ULK3 reviewed Kinase ULK3 Kd apparent '>' 30000 nM
P55263 BXGT011115 Adenosine kinase reviewed Kinase ADK Kd apparent '>' 30000 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Kd apparent '>' 30000 nM
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D Kd apparent '>' 30000 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Kd apparent '>' 30000 nM
Q15208 BXGT013550 Serine/threonine-protein kinase 38 reviewed Kinase STK38 Kd apparent '>' 30000 nM
Q15375 BXGT013562 Ephrin type-A receptor 7 reviewed Kinase EPHA7 Kd apparent '>' 30000 nM
P37173 BXGT009970 TGF-beta receptor type-2 reviewed Kinase TGFBR2 Kd apparent '>' 30000 nM
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 reviewed Kinase TBK1 Kd apparent '>' 30000 nM
P43686 BXGT010409 26S proteasome regulatory subunit 6B reviewed Enzyme PSMC4 Kd apparent '>' 30000 nM
P30085 BXGT009399 UMP-CMP kinase reviewed Kinase CMPK1 Kd apparent '>' 30000 nM
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Kd apparent '>' 30000 nM
P35580 BXGT009853 Myosin-10 reviewed - MYH10 Kd apparent '>' 30000 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Kd apparent '>' 30000 nM
P42680 BXGT010329 Tyrosine-protein kinase Tec reviewed Kinase TEC Kd apparent '>' 30000 nM
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 reviewed Kinase PRKD2 Kd apparent '>' 30000 nM
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 reviewed Kinase TYK2 Kd apparent '>' 30000 nM
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 reviewed Kinase MAP3K20 Kd apparent '>' 30000 nM
P21709 BXGT008685 Ephrin type-A receptor 1 reviewed Kinase EPHA1 Kd apparent '>' 30000 nM
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Kd apparent '>' 30000 nM
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Kd apparent '>' 30000 nM
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Kd apparent '>' 30000 nM
P53671 BXGT011009 LIM domain kinase 2 reviewed Kinase LIMK2 Kd apparent '>' 30000 nM
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret reviewed Kinase RET Kd apparent '>' 30000 nM
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 reviewed Kinase RIPK2 Kd apparent '>' 30000 nM
Q9Y2U5 BXGT022248 Mitogen-activated protein kinase kinase kinase 2 reviewed Kinase MAP3K2 Kd apparent '>' 30000 nM
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 reviewed Kinase PAK2 Kd apparent '>' 30000 nM
Q07912 BXGT012947 Activated CDC42 kinase 1 reviewed Kinase TNK2 Kd apparent '>' 30000 nM
P16591 BXGT008246 Tyrosine-protein kinase Fer reviewed Kinase FER Kd apparent '>' 30000 nM
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Kd apparent '>' 30000 nM
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Kd apparent '>' 30000 nM
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK Kd apparent '>' 30000 nM
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Kd apparent '>' 30000 nM
P36896 BXGT009940 Activin receptor type-1B reviewed Kinase ACVR1B Kd apparent '>' 30000 nM
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Kd apparent '>' 30000 nM
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 reviewed Enzyme modulator PRKAG2 Kd apparent '>' 30000 nM
P42685 BXGT010332 Tyrosine-protein kinase FRK reviewed Kinase FRK Kd apparent '>' 30000 nM
P61026 BXGT011351 Ras-related protein Rab-10 reviewed - RAB10 Kd apparent '>' 30000 nM
Q5HYI8 BXGT015421 Rab-like protein 3 reviewed - RABL3 Kd apparent '>' 30000 nM
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps reviewed Kinase FES Kd apparent '>' 30000 nM
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial reviewed Enzyme modulator OPA1 Kd apparent '>' 30000 nM
Q99640 BXGT019944 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase reviewed Kinase PKMYT1 Kd apparent '>' 30000 nM
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Kd apparent '>' 30000 nM
O00764 BXGT003948 Pyridoxal kinase reviewed Kinase PDXK Kd apparent '>' 30000 nM
P61158 BXGT011364 Actin-related protein 3 reviewed Cellular structure ACTR3 Kd apparent '>' 30000 nM
P54577 BXGT011055 Tyrosine--tRNA ligase, cytoplasmic reviewed Enzyme YARS1 Kd apparent '>' 30000 nM
Q13164 BXGT013322 Mitogen-activated protein kinase 7 reviewed Kinase MAPK7 Kd apparent '>' 30000 nM
P46734 BXGT010537 Dual specificity mitogen-activated protein kinase kinase 3 reviewed Kinase MAP2K3 Kd apparent '>' 30000 nM
P54756 BXGT011074 Ephrin type-A receptor 5 reviewed Kinase EPHA5 Kd apparent '>' 30000 nM
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 reviewed Kinase RIPK3 Kd apparent '>' 30000 nM
P11388 BXGT007697 DNA topoisomerase 2-alpha reviewed - TOP2A Kd apparent '=' 486 nM
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A reviewed Kinase BMPR1A Kd apparent '>' 30000 nM
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Kd apparent '>' 30000 nM
P29317 BXGT009331 Ephrin type-A receptor 2 reviewed Kinase EPHA2 Kd apparent '>' 30000 nM
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Kd apparent '>' 30000 nM
O75582 BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 Kd apparent '>' 30000 nM
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Kd apparent '>' 30000 nM
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Kd apparent '>' 30000 nM
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 Kd apparent '>' 30000 nM
Q96S44 BXGT019738 EKC/KEOPS complex subunit TP53RK reviewed Kinase TP53RK Kd apparent '>' 30000 nM
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Kd apparent '>' 30000 nM
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Kd apparent '>' 30000 nM
Q15131 BXGT013545 Cyclin-dependent kinase 10 reviewed Kinase CDK10 Kd apparent '>' 30000 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Kd apparent '>' 30000 nM
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Kd apparent '>' 30000 nM
Q14839 BXGT013509 Chromodomain-helicase-DNA-binding protein 4 reviewed - CHD4 Kd apparent '>' 30000 nM
Q9Y6E0 BXGT022327 Serine/threonine-protein kinase 24 reviewed Kinase STK24 Kd apparent '>' 30000 nM
Q02880 BXGT012677 DNA topoisomerase 2-beta reviewed - TOP2B Kd apparent '>' 30000 nM
O95835 BXGT005400 Serine/threonine-protein kinase LATS1 reviewed Kinase LATS1 Kd apparent '>' 30000 nM
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 Kd apparent '>' 30000 nM
Q01813 BXGT012618 ATP-dependent 6-phosphofructokinase, platelet type reviewed Kinase PFKP Kd apparent '>' 30000 nM
P54760 BXGT011075 Ephrin type-B receptor 4 reviewed Kinase EPHB4 Kd apparent '>' 30000 nM
P49674 BXGT010725 Casein kinase I isoform epsilon reviewed - CSNK1E Kd apparent '>' 30000 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Kd apparent '>' 30000 nM
P61160 BXGT011365 Actin-related protein 2 reviewed Cellular structure ACTR2 Kd apparent '>' 30000 nM
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 reviewed Kinase RPS6KA1 Kd apparent '>' 30000 nM
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Kd apparent '>' 30000 nM
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X reviewed - DDX3X Kd apparent '>' 30000 nM
Q9UPZ9 BXGT021804 Serine/threonine-protein kinase ICK reviewed Kinase CILK1 Kd apparent '>' 30000 nM
Q04912 BXGT012790 Macrophage-stimulating protein receptor reviewed Kinase MST1R Kd apparent '>' 30000 nM
Q8TBX8 BXGT018791 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma reviewed Kinase PIP4K2C Kd apparent '>' 30000 nM
Q9NTK5 BXGT021213 Obg-like ATPase 1 reviewed Enzyme modulator OLA1 Kd apparent '>' 30000 nM
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 reviewed Kinase MARK2 Kd apparent '>' 30000 nM
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 reviewed Kinase MAP3K1 Kd apparent '>' 30000 nM
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Kd apparent '>' 30000 nM
Q15392 BXGT013566 Delta(24)-sterol reductase reviewed Enzyme DHCR24 Kd apparent '>' 30000 nM
Q16584 BXGT013642 Mitogen-activated protein kinase kinase kinase 11 reviewed Kinase MAP3K11 Kd apparent '>' 30000 nM
P27448 BXGT009183 MAP/microtubule affinity-regulating kinase 3 reviewed Kinase MARK3 Kd apparent '>' 30000 nM
P31153 BXGT009512 S-adenosylmethionine synthase isoform type-2 reviewed Enzyme MAT2A Kd apparent '>' 30000 nM
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Kd apparent '>' 30000 nM
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 reviewed Enzyme NDUFA13 Kd apparent '>' 30000 nM
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial reviewed Enzyme SUCLA2 Kd apparent '>' 30000 nM
P09619 BXGT006911 Platelet-derived growth factor receptor beta reviewed Kinase PDGFRB Kd apparent '>' 30000 nM
P12236 BXGT007775 ADP/ATP translocase 3 reviewed Transporter SLC25A6 Kd apparent '>' 30000 nM
P10398 BXGT007564 Serine/threonine-protein kinase A-Raf reviewed Kinase ARAF Kd apparent '>' 30000 nM
Q9UK32 BXGT021736 Ribosomal protein S6 kinase alpha-6 reviewed Kinase RPS6KA6 Kd apparent '>' 30000 nM
P36897 BXGT009941 TGF-beta receptor type-1 reviewed Kinase TGFBR1 Kd apparent '>' 30000 nM
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 reviewed Kinase RPS6KB1 Kd apparent '>' 30000 nM
Q92918 BXGT019394 Mitogen-activated protein kinase kinase kinase kinase 1 reviewed Kinase MAP4K1 Kd apparent '>' 30000 nM
P42684 BXGT010331 Tyrosine-protein kinase ABL2 reviewed Kinase ABL2 Kd apparent '>' 30000 nM
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Kd apparent '>' 30000 nM
P42285 BXGT010297 Exosome RNA helicase MTR4 reviewed - MTREX Kd apparent '>' 30000 nM
Q6ZSR9 BXGT016637 Uncharacterized protein FLJ45252 reviewed - Kd apparent '>' 30000 nM
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Kd apparent '>' 30000 nM
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 reviewed Kinase TAOK2 Kd apparent '>' 30000 nM
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 Kd apparent '>' 30000 nM
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Kd apparent '>' 30000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Kd apparent '>' 30000 nM
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Kd apparent '>' 30000 nM
P50613 BXGT010815 Cyclin-dependent kinase 7 reviewed Kinase CDK7 Kd apparent '>' 30000 nM
Q9NU22 BXGT021214 Midasin reviewed - MDN1 Kd apparent '>' 30000 nM
O14578 BXGT004072 Citron Rho-interacting kinase reviewed Kinase CIT Kd apparent '>' 30000 nM
P54764 BXGT011078 Ephrin type-A receptor 4 reviewed Kinase EPHA4 Kd apparent '>' 30000 nM
P54819 BXGT011084 Adenylate kinase 2, mitochondrial reviewed Kinase AK2 Kd apparent '>' 30000 nM
Q00526 BXGT012531 Cyclin-dependent kinase 3 reviewed Kinase CDK3 Kd apparent '>' 30000 nM
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Kd apparent '>' 30000 nM
Q6DT37 BXGT016259 Serine/threonine-protein kinase MRCK gamma reviewed Kinase CDC42BPG Kd apparent '>' 30000 nM
P27707 BXGT009201 Deoxycytidine kinase reviewed Kinase DCK Kd apparent '>' 30000 nM
Q9BQI3 BXGT020113 Eukaryotic translation initiation factor 2-alpha kinase 1 reviewed Kinase EIF2AK1 Kd apparent '>' 30000 nM
Q9H0K1 BXGT020438 Serine/threonine-protein kinase SIK2 reviewed Kinase SIK2 Kd apparent '>' 30000 nM
P30519 BXGT009429 Heme oxygenase 2 reviewed - HMOX2 Kd apparent '>' 30000 nM
Q13882 BXGT013399 Protein-tyrosine kinase 6 reviewed Kinase PTK6 Kd apparent '>' 30000 nM
P38117 BXGT010027 Electron transfer flavoprotein subunit beta reviewed Enzyme ETFB Kd apparent '>' 30000 nM
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Kd apparent '>' 30000 nM
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Kd apparent '>' 30000 nM
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Kd apparent '>' 30000 nM
P30291 BXGT009417 Wee1-like protein kinase reviewed Kinase WEE1 Kd apparent '>' 30000 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Kd apparent '>' 30000 nM
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Kd apparent '>' 30000 nM
O95382 BXGT005376 Mitogen-activated protein kinase kinase kinase 6 reviewed Kinase MAP3K6 Kd apparent '>' 30000 nM
Q13418 BXGT013351 Integrin-linked protein kinase reviewed Kinase ILK Kd apparent '>' 30000 nM
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 reviewed Kinase GRK2 Kd apparent '>' 30000 nM
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Kd apparent '>' 30000 nM
P49411 BXGT010703 Elongation factor Tu, mitochondrial reviewed Enzyme TUFM Kd apparent '>' 30000 nM
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 reviewed Kinase ERN1 Kd apparent '>' 30000 nM
P04899 BXGT006281 Guanine nucleotide-binding protein G(i) subunit alpha-2 reviewed Enzyme modulator GNAI2 Kd apparent '>' 30000 nM
Q92499 BXGT019350 ATP-dependent RNA helicase DDX1 reviewed - DDX1 Kd apparent '>' 30000 nM
O75716 BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 Kd apparent '>' 30000 nM
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 reviewed Kinase MAP2K2 Kd apparent '>' 30000 nM
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 Kd apparent '>' 30000 nM
P06737 BXGT006492 Glycogen phosphorylase, liver form reviewed Enzyme PYGL Kd apparent '>' 30000 nM
P13861 BXGT007961 cAMP-dependent protein kinase type II-alpha regulatory subunit reviewed - PRKAR2A Kd apparent '>' 30000 nM
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Kd apparent '>' 30000 nM
P22694 BXGT008797 cAMP-dependent protein kinase catalytic subunit beta reviewed Kinase PRKACB Kd apparent '>' 30000 nM
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha reviewed Kinase CDC42BPA Kd apparent '>' 30000 nM
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Kd apparent '>' 30000 nM
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Kd apparent '>' 30000 nM
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 reviewed Kinase IRAK4 Kd apparent '>' 30000 nM
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Kd apparent '>' 30000 nM
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 reviewed Kinase DDR1 Kd apparent '>' 30000 nM
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 reviewed Kinase NEK1 Kd apparent '>' 30000 nM
P48729 BXGT010655 Casein kinase I isoform alpha reviewed Kinase CSNK1A1 Kd apparent '>' 30000 nM
P29323 BXGT009334 Ephrin type-B receptor 2 reviewed Kinase EPHB2 Kd apparent '>' 30000 nM
P51159 BXGT010839 Ras-related protein Rab-27A reviewed - RAB27A Kd apparent '>' 30000 nM
Q9ULC5 BXGT021758 Long-chain-fatty-acid--CoA ligase 5 reviewed Enzyme ACSL5 Kd apparent '>' 30000 nM
O15254 BXGT004143 Peroxisomal acyl-coenzyme A oxidase 3 reviewed Enzyme ACOX3 Kd apparent '>' 30000 nM
Q7L7X3 BXGT016997 Serine/threonine-protein kinase TAO1 reviewed Kinase TAOK1 Kd apparent '>' 30000 nM
Q8TD19 BXGT018804 Serine/threonine-protein kinase Nek9 reviewed Kinase NEK9 Kd apparent '>' 30000 nM
Q76MJ5 BXGT016871 Serine/threonine-protein kinase/endoribonuclease IRE2 reviewed Kinase ERN2 Kd apparent '>' 30000 nM
O00264 BXGT003904 Membrane-associated progesterone receptor component 1 reviewed Signaling PGRMC1 Kd apparent '>' 30000 nM
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD reviewed Enzyme ERCC2 Kd apparent '>' 30000 nM
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 reviewed Enzyme modulator PEBP1 Kd apparent '>' 30000 nM
O95347 BXGT005374 Structural maintenance of chromosomes protein 2 reviewed - SMC2 Kd apparent '>' 30000 nM
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 reviewed Kinase BUB1 Kd apparent '>' 30000 nM
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 reviewed Kinase MAP2K1 Kd apparent '>' 30000 nM
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Kd apparent '>' 30000 nM
O75676 BXGT005144 Ribosomal protein S6 kinase alpha-4 reviewed Kinase RPS6KA4 Kd apparent '>' 30000 nM
P22234 BXGT008745 Multifunctional protein ADE2 reviewed Enzyme PAICS Kd apparent '>' 30000 nM
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Kd apparent '>' 30000 nM
P41240 BXGT010242 Tyrosine-protein kinase CSK reviewed Kinase CSK Kd apparent '>' 30000 nM
Q7Z406 BXGT017251 Myosin-14 reviewed - MYH14 Kd apparent '>' 30000 nM
Q9Y6R4 BXGT022340 Mitogen-activated protein kinase kinase kinase 4 reviewed Kinase MAP3K4 Kd apparent '>' 30000 nM
P50750 BXGT010818 Cyclin-dependent kinase 9 reviewed Kinase CDK9 Kd apparent '>' 30000 nM
Q8IVH8 BXGT018345 Mitogen-activated protein kinase kinase kinase kinase 3 reviewed Kinase MAP4K3 Kd apparent '>' 30000 nM
P12268 BXGT007783 Inosine-5'-monophosphate dehydrogenase 2 reviewed Enzyme IMPDH2 Kd apparent '>' 30000 nM
Q9NSD9 BXGT021206 Phenylalanine--tRNA ligase beta subunit reviewed Enzyme FARSB Kd apparent '>' 30000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00514 Ostrich fern Matteuccia struthiopteris Vegetables
BXGF00985 Tabebuia rosea Tabebuia rosea Human Edible Plant
BXGF01019 Sinopodophyllum hexandrum Sinopodophyllum hexandrum Medicinal Plant
BXGF01197 Lathyrus macrorrhizus Lathyrus macrorrhizus Others
BXGF01300 Escallonia philippiana Escallonia philippiana Others
BXGF01482 Aglaia meridionalis Aglaia meridionalis Others
BXGF01607 Arcangelisia gusanlung Arcangelisia gusanlung Human Edible Plant
BXGF01650 Hippocratea indica Hippocratea indica Others
BXGF01657 Swertia paniculata Swertia paniculata Medicinal Plant
BXGF02019 Entandrophragma cylindricum Entandrophragma cylindricum Others
BXGF02080 Tanacetum santolina Tanacetum santolina Others
BXGF02354 Dunaliella acidophila Dunaliella acidophila Others
BXGF02379 Leptospermum scoparium Leptospermum scoparium Medicinal Plant
BXGF02414 Senecio erraticus Senecio erraticus Others
BXGF02434 Chamaemelum scariosum Chamaemelum scariosum Others
BXGF02457 Magnolia acuminata Magnolia acuminata Medicinal Plant
BXGF02506 Ficus maxima Ficus maxima Medicinal Plant
BXGF02533 Timonius kaniensis Timonius kaniensis Others
BXGF02534 Artemisia schmidtiana Artemisia schmidtiana Medicinal Plant
BXGF02559 Simmondsia chinensis Simmondsia chinensis Human Edible Plant
BXGF02571 Millettia racemosa Millettia racemosa Medicinal Plant
BXGF02645 Gleichenia glauca Gleichenia glauca Others
BXGF02657 Juniperus thurifera Juniperus thurifera Others
BXGF02704 Helipterum strictum Helipterum strictum Others
BXGF02741 Allium ursinum Allium ursinum Medicinal Plant
BXGF02755 Crotalaria lechnaultii Crotalaria lechnaultii Others
BXGF02769 Copaifera paupera Copaifera paupera Others
BXGF02798 Cleidion brevipetiolatum Cleidion brevipetiolatum Human Edible Plant
BXGF02834 Citrus tankan Citrus tankan Medicinal Plant
BXGF02844 Brickellia pendula Brickellia pendula Others
BXGF03348 Panax notoginseng Panax notoginseng Medicinal Plant
BXGF03357 Coleus carnosus Coleus carnosus Medicinal Plant
BXGF04028 Plumbago europaea Plumbago europaea Medicinal Plant
BXGF04324 Diphylleia sinensis Diphylleia sinensis Medicinal Plant
BXGF04939 Schefflera capitata Schefflera capitata Others
BXGF05146 Hesperocyparis nevadensis Hesperocyparis nevadensis Others
BXGF05280 Senecio mexicanus Senecio mexicanus Others
BXGF05292 Croton nitens Croton nitens Others
BXGF05417 Diphylleia grayi Diphylleia grayi Medicinal Plant
BXGF05530 Ophioglossum vulgatum Ophioglossum vulgatum Medicinal Plant
BXGF05744 Dimorphotheca sinuata Dimorphotheca sinuata Others
BXGF05782 Ammi majus Ammi majus Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease