Showing entry for Plastin-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007956
Protein NamePlastin-2
Uniport IdP13796
GeneLCP1
Gene Id3936
DomainCH; EF-hand_1
Pfam PF00307   PF13499  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051017 actin filament bundle assembly
Biological Process GO:0051639 actin filament network formation
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0016477 cell migration
Biological Process GO:0022617 extracellular matrix disassembly
Biological Process GO:0035722 interleukin-12-mediated signaling pathway
Biological Process GO:0071803 positive regulation of podosome assembly
Biological Process GO:0010737 protein kinase A signaling
Biological Process GO:0033157 regulation of intracellular protein transport
Biological Process GO:0002286 T cell activation involved in immune response
molecular function GO:0003779 actin binding
molecular function GO:0051015 actin filament binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0051020 GTPase binding
molecular function GO:0042802 identical protein binding
molecular function GO:0005178 integrin binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005884 actin filament
cellular component GO:0032432 actin filament bundle
cellular component GO:0030054 cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0030175 filopodium
cellular component GO:0005925 focal adhesion
cellular component GO:0001891 phagocytic cup
cellular component GO:0005886 plasma membrane
cellular component GO:0002102 podosome
cellular component GO:0001726 ruffle
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-447115 Interleukin-12 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-9020591 Interleukin-12 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0040332 BXGD002858 Tobacco Dependence Chemically-Induced Disorders; Mental Disorders
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376384 BXGD007995 Nicotine Use Disorder Chemically-Induced Disorders; Mental Disorders
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0521158 BXGD009130 Recurrent tumor
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0745091 BXGD010113 Hypereosinophilia Hemic and Lymphatic Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1739135 BXGD013733 Progression of prostate cancer
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein