Showing entry for Corticosteroid 11-beta-dehydrogenase isozyme 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008207
Protein NameCorticosteroid 11-beta-dehydrogenase isozyme 1
Uniport IdP16232
GeneHsd11b1
Gene Id25116
Domainadh_short
Pfam PF00106  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0006704 glucocorticoid biosynthetic process
Biological Process GO:0006713 glucocorticoid catabolic process
Biological Process GO:0030324 lung development
Biological Process GO:0043456 regulation of pentose-phosphate shunt
Biological Process GO:0031667 response to nutrient levels
Biological Process GO:0006706 steroid catabolic process
molecular function GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity
molecular function GO:0050661 NADP binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0005496 steroid binding
cellular component GO:0045177 apical part of cell
cellular component GO:0005737 cytoplasm
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0031965 nuclear membrane
cellular component GO:0005791 rough endoplasmic reticulum
molecular function GO:0003845 11-beta-hydroxysteroid dehydrogenase NAD(P) activity
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0011627 Glycyrrhetic acid 470.69
BXGC0013582 Curcumin 368.13
BXGC0024810 curcumin 368.13
BXGC0029810 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)-1,4-Pentadien-3-One 326.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein