Showing entry for Granzyme H


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008595
Protein NameGranzyme H
Uniport IdP20718
GeneGZMH
Gene Id2999
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0019835 cytolysis
molecular function GO:0004252 serine-type endopeptidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins
R-HSA-2980736 Peptide hormone metabolism
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-392499 Metabolism of proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0029455 BXGD002156 Osteopoikilosis (disorder) Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0029464 BXGD002161 Osteosclerosis Musculoskeletal Diseases
C0221032 BXGD004374 Familial generalized lipodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0271694 BXGD006239 Familial partial lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0392788 BXGD008070 Nasal Type Extranodal NK/T-Cell Lymphoma Neoplasms
C4511302 BXGD022999 Genetic lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein