adisease

Showing entry for Osteosclerosis

General Disease Information
BXGD Id	BXGD002161
Disease Name	Osteosclerosis
Disease CUI Id	C0029464
MeSH Codes	C05
Disease Class Name	Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000924
Human Phenotype Ontology Term	Abnormality of the skeletal system
Disease Ontology Id	DOID:630 DOID:7
Disease Ontology Class Name	genetic disease; disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02818	BXGT005969	Osteocalcin	632	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13945	BXGT007972	Beta-3 adrenergic receptor	155	reviewed	G-protein coupled receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P20718	BXGT008595	Granzyme H	2999	reviewed	Enzyme
P21333	BXGT008638	Filamin-A	2316	reviewed
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P24557	BXGT008976	Thromboxane-A synthase	6916	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
P20809	BXGT025043	Interleukin-11	3589	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}