Showing entry for V-type proton ATPase subunit C 1



                       
General Target Information
BXGT IdBXGT008634
Protein NameV-type proton ATPase subunit C 1
Uniport IdP21283
GeneATP6V1C1
Gene Id528
DomainV-ATPase_C
Pfam PF03223  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.2 Energy metabolism hsa00190 Oxidative phosphorylation
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04721 Synaptic vesicle cycle
5. Organismal Systems 5.5 Excretory system hsa04966 Collecting duct acid secretion
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05110 Vibrio cholerae infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.3 Immune diseases hsa05323 Rheumatoid arthritis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0090383 phagosome acidification
Biological Process GO:1902600 proton transmembrane transport
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0033572 transferrin transport
molecular function GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism
molecular function GO:0046961 proton-transporting ATPase activity, rotational mechanism
molecular function GO:0005215 transporter activity
cellular component GO:0045177 apical part of cell
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005765 lysosomal membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0016469 proton-transporting two-sector ATPase complex
cellular component GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain
Reactome
Pathway Id Pathway Name
R-HSA-1222556 ROS and RNS production in phagocytes
R-HSA-162582 Signal Transduction
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-2262752 Cellular responses to stress
R-HSA-382551 Transport of small molecules
R-HSA-74752 Signaling by Insulin receptor
R-HSA-77387 Insulin receptor recycling
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-917937 Iron uptake and transport
R-HSA-917977 Transferrin endocytosis and recycling
R-HSA-9639288 Amino acids regulate mTORC1
R-HSA-983712 Ion channel transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011405 BXGD000719 Dental Pulp Diseases Stomatognathic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0333307 BXGD006946 Superficial ulcer Pathological Conditions, Signs and Symptoms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C3887524 BXGD019892 Skin Erosion Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000076 p-Coumaroyl tartaric acid glucosidic ester 150.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein