adisease

Showing entry for Skin Erosion

General Disease Information
BXGD Id	BXGD019892
Disease Name	Skin Erosion
Disease CUI Id	C3887524
MeSH Codes	C17
Disease Class Name	Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	3551	reviewed	Kinase
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95257	BXGT005365	Growth arrest and DNA damage-inducible protein GADD45 gamma	10912	reviewed
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P14923	BXGT008069	Junction plakoglobin	3728	reviewed
P15086	BXGT008078	Carboxypeptidase B	1360	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P16070	BXGT008186	CD44 antigen	960	reviewed
P16144	BXGT008200	Integrin beta-4	3691	reviewed	Receptor
P17301	BXGT008299	Integrin alpha-2	3673	reviewed
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P21283	BXGT008634	V-type proton ATPase subunit C 1	528	reviewed	Transporter
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28068	BXGT009229	HLA class II histocompatibility antigen, DM beta chain	3109	reviewed	Immune response
P29372	BXGT009336	DNA-3-methyladenine glycosylase	4350	reviewed	Enzyme
P30536	BXGT009435	Translocator protein	706	reviewed
P30626	BXGT009450	Sorcin	6717	reviewed
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P35442	BXGT009832	Thrombospondin-2	7058	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	8140	reviewed	Transporter
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15020	BXGT013522	Squamous cell carcinoma antigen recognized by T-cells 3	9733	reviewed	Nucleic acid binding
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15554	BXGT013577	Telomeric repeat-binding factor 2	7014	reviewed
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q6ZMJ4	BXGT016628	Interleukin-34	146433	reviewed
Q7KZF4	BXGT016989	Staphylococcal nuclease domain-containing protein 1	27044	reviewed	Transcription factor
Q8IU54	BXGT018331	Interferon lambda-1	282618	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96H15	BXGT019669	T-cell immunoglobulin and mucin domain-containing protein 4	91937	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H015	BXGT020432	Solute carrier family 22 member 4	6583	reviewed	Transporter
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9ULW0	BXGT021766	Targeting protein for Xklp2	22974	reviewed	Cellular structure
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9UQ84	BXGT021807	Exonuclease 1	9156	reviewed	Enzyme
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
Q9Y5W5	BXGT022303	Wnt inhibitory factor 1	11197	reviewed	Calcium-binding protein
Q9UNS1	BXGT022882	Protein timeless homolog	8914	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q9Y294	BXGT023981	Histone chaperone ASF1A	25842	reviewed	Nucleic acid binding
P16104	BXGT024571	Histone H2AX	3014	reviewed	Nucleic acid binding
A6NHR9	BXGT024875	Structural maintenance of chromosomes flexible hinge domain-containing protein 1	23347	reviewed
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}