Showing entry for p-Coumaroyl tartaric acid glucosidic ester


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000076
Compound Namep-Coumaroyl tartaric acid glucosidic ester
Structure
FormulaC4H6O6
InchiKeyFEWJPZIEWOKRBE-LWMBPPNESA-N
SMILESO[C@@H]([C@H](O)C(O)=O)C(O)=O
InchiInChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m0/s1
IUPAC(2S,3S)-2,3-dihydroxybutanedioic acid
Molecular Weight150.09
Pubchem Id439655
Chembl IdCHEMBL1200861
Targets of Information Source
DrugBank DB01694
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P37672 BXGT010002 2,3-diketo-L-gulonate reductase reviewed - dlgD experimental -
Q9P2W7 BXGT021306 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 reviewed Enzyme B3GAT1 experimental -
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 reviewed - TREM1 experimental -
P26196 BXGT009089 Probable ATP-dependent RNA helicase DDX6 reviewed - DDX6 experimental -
Q746J6 BXGT016797 Cytochrome P450 unreviewed - TT_P0059 experimental -
Q9NWT6 BXGT021234 Hypoxia-inducible factor 1-alpha inhibitor reviewed - HIF1AN experimental -
P9WNX3 BXGT012430 D-3-phosphoglycerate dehydrogenase reviewed - serA experimental -
O25927 BXGT004266 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase reviewed - lpxA experimental -
P21283 BXGT008634 V-type proton ATPase subunit C 1 reviewed Transporter ATP6V1C1 experimental -
Q9HU21 BXGT020601 dTDP-4-dehydrorhamnose 3,5-epimerase reviewed - rmlC experimental -
Q9KVB4 BXGT021008 Uncharacterized protein unreviewed - VC_0232 experimental -
Q51782 BXGT014964 Phosphonoacetate hydrolase reviewed - phnA experimental -
A0A0H2URW2 BXGT000277 Uncharacterized protein unreviewed - SP_1951 experimental -
PDB TAR
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P80077 BXGT011877 Glutamate mutase epsilon subunit reviewed glmE - >10000000 - - -
Q14849 BXGT013510 StAR-related lipid transfer protein 3 reviewed STARD3 - - - - -
P32851 BXGT009671 Syntaxin-1A reviewed Stx1a - - - - -
P00722 BXGT005626 Beta-galactosidase reviewed lacZ - - - - -
Q9NWT6 BXGT021234 Hypoxia-inducible factor 1-alpha inhibitor reviewed HIF1AN - - - - -
P20646 BXGT008590 Prostatic acid phosphatase reviewed Acp3 - - - - -
Q9DU47 BXGT020276 Polyprotein unreviewed ORF1 - - - - -
P9WNX3 BXGT012430 D-3-phosphoglycerate dehydrogenase reviewed serA - - - - -
Q9F4C9 BXGT020343 Restriction endonuclease unreviewed R - - - - -
Q9LYU8 BXGT021096 Aspartokinase 1, chloroplastic reviewed AK1 - - - - -
P18429 BXGT008402 Endo-1,4-beta-xylanase A reviewed xynA - - - - -
O66188 BXGT004937 Thiocyanate hydrolase subunit gamma reviewed scnC - - - - -
P0A8P1 BXGT007151 Leucyl/phenylalanyl-tRNA--protein transferase reviewed aat - - - - -
Q89FH0 BXGT017741 D(-)-tartrate dehydratase reviewed tarD - - - - -
P38051 BXGT010024 Isochorismate synthase MenF reviewed menF - - - - -
P68175 BXGT011585 Strictosidine synthase reviewed STR1 - - - - -
P02883 BXGT005983 Thaumatin I reviewed - - - - -
P00698 BXGT005617 Lysozyme C reviewed LYZ - - - - -
Q9LCV9 BXGT021071 N(2)-(2-carboxyethyl)arginine synthase reviewed ceaS - - - - -
P48546 BXGT010642 Gastric inhibitory polypeptide receptor reviewed GIPR G-protein coupled receptor - - - -
P56817 BXGT011200 Beta-secretase 1 reviewed BACE1 Enzyme - - - -
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed PLK1 Kinase - - - -
P04585 BXGT006234 Gag-Pol polyprotein reviewed gag-pol - - - - -
P9WNW7 BXGT012428 Iron-dependent extradiol dioxygenase reviewed hsaC - - - - -
P35236 BXGT009802 Tyrosine-protein phosphatase non-receptor type 7 reviewed PTPN7 Enzyme - - - -
Q9KA87 BXGT020888 Dipicolinate synthase subunit A unreviewed spoVFA - - - - -
Q77E03 BXGT016883 Nucleoprotein reviewed N - - - - -
P0AEX9 BXGT007333 Maltose/maltodextrin-binding periplasmic protein reviewed malE - - - - -
P17174 BXGT008289 Aspartate aminotransferase, cytoplasmic reviewed GOT1 - - - - -
Q45070 BXGT014610 Glucuronoxylanase XynC reviewed xynC - - - - -
Q9KKZ8 BXGT020936 Transcriptional regulator, LuxR family unreviewed VC_A0952 - - - - -
C7U112 BXGT002618 Adenylate kinase unreviewed ak - - - - -
P37128 BXGT009965 GDP-mannose pyrophosphatase NudK reviewed nudK - - - - -
D3EID5 BXGT002877 Mandelate racemase/muconate lactonizing protein unreviewed GYMC10_3367 - - - - -
Q6CUC5 BXGT016229 KLLA0C05984p unreviewed KLLA0_C05984g - - - - -
Q2YQ74 BXGT014278 Beta-lactamase-like unreviewed BAB1_1016 - - - - -
P86292 BXGT012088 Cofilin/actin-depolymerizing factor homolog 1 reviewed - - - - -
B0TZW0 BXGT001861 L-amino acid-D/L-Glu epimerase reviewed Fphi_1647 - - - - -
Q13PB7 BXGT013421 Uncharacterized protein unreviewed Bxe_B1897 - - - - -
A0A0J1HJU0 BXGT000498 Inosine-5'-monophosphate dehydrogenase unreviewed guaB - - - - -
P31129 BXGT009508 Diguanylate cyclase DgcZ reviewed dgcZ - - - - -
A3DJ38 BXGT001146 Metallophosphoesterase unreviewed Cthe_2768 - - - - -
D2YW46 BXGT002864 Putative fumarylacetoacetate isomerase/hydrolase unreviewed - - - - -
P17654 BXGT008324 Alpha-amylase reviewed AMY1.1 - - - - -
Q9C169 BXGT020212 Catalase-3 reviewed cat-3 - - - - -
P23946 BXGT008932 Chymase reviewed CMA1 Enzyme - - - -
P03950 BXGT006116 Angiogenin reviewed ANG - - - - -
G0L2Y1 BXGT003365 Alginate lyase, family PL7 unreviewed alyA5 - - - - -
O31266 BXGT004389 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase reviewed hod - - - - -
A9JQL9 BXGT001792 4,4'-diapophytoene synthase reviewed crtM - - - - -
Q8GME8 BXGT018164 Acyl-CoA thioesterase unreviewed DIJ69_33980 - - - - -
Q6CP22 BXGT016224 KLLA0E08119p unreviewed KLLA0_E08119g - - - - -
Q2FZK7 BXGT014038 Bifunctional autolysin reviewed atl - - - - -
Q01469 BXGT012590 Fatty acid-binding protein 5 reviewed FABP5 - - - - -
P0A1C7 BXGT006982 Propanediol utilization protein PduA reviewed pduA - - - - -
Q9BVA6 BXGT020143 Protein adenylyltransferase FICD reviewed FICD - - - - -
A3DJS9 BXGT001148 Carbohydrate binding family 6 unreviewed Cthe_3012 - - - - -
O28126 BXGT004298 CCA-adding enzyme reviewed cca - - - - -
K7SWE7 BXGT003801 Formate--tetrahydrofolate ligase unreviewed fhs1 - - - - -
M1VUY5 BXGT003853 Uncharacterized protein unreviewed CPUR_02269 - - - - -
Q08414 BXGT012984 Nourseothricin acetyltransferase unreviewed nat1 - - - - -
Q187F5 BXGT013725 Putative conjugative transposon protein Tn1549-like, CTn5-Orf2 unreviewed CD630_18460 - - - - -
Q6VZ86 BXGT016587 CNPV261 Holliday junction resolvase protein unreviewed CNPV261 - - - - -
P03420 BXGT006067 Fusion glycoprotein F0 reviewed F - - - - -
P01887 BXGT005808 Beta-2-microglobulin reviewed B2m - - - - -
D1AWE0 BXGT002785 Extracellular solute-binding protein family 1 unreviewed Smon_0123 - - - - -
Q8BHN3 BXGT017912 Neutral alpha-glucosidase AB reviewed Ganab - - - - -
D2TPI3 BXGT002852 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase unreviewed bioA - - - - -
Q7Z144 BXGT017243 MMACHC-like protein reviewed cblc-1 - - - - -
Q52424 BXGT014976 Aminoglycoside 2'-N-acetyltransferase reviewed aac - - - - -
Q13W28 BXGT013428 Trehalose-6-phosphate synthase unreviewed Bxe_A1242 - - - - -
F1LJ99 BXGT003213 Cis-epoxysuccinate hydrolase unreviewed - - - - -
B2JVW0 BXGT001991 3-dehydroquinate dehydratase unreviewed aroQ - - - - -
P80077 BXGT011877 Glutamate mutase epsilon subunit reviewed glmE - - - - -
A0A1J6PWI8 BXGT024516 M23 family metallopeptidase unreviewed A8118_01115 - - - - -
A0A3B6UEU3 BXGT023876 ScoE protein unreviewed ScoE - - - - -
P19235 BXGT022895 Erythropoietin receptor reviewed EPOR Receptor - - - -
Q04TM5 BXGT012800 N-acetylneuraminic acid (Sialic acid) synthetase unreviewed LBJ_1133 - - - - -
A0A485ICL5 BXGT025674 Glutathione S-transferase unreviewed yfcG_4 - - - - -
D0CCF6 BXGT025933 4-aminobutyrate transaminase unreviewed gabT - - - - -
C6XW09 BXGT025957 Aminodeoxyfutalosine synthase unreviewed mqnE - - - - -
Q04771 BXGT012783 Activin receptor type-1 reviewed ACVR1 Kinase - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL1200861
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 1584 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
Q969S8 BXGT019613 Polyamine deacetylase HDAC10 reviewed Epigenetic regulator HDAC10 Activity '=' 90 %
Q9UKV0 BXGT021750 Histone deacetylase 9 reviewed Epigenetic regulator HDAC9 Activity '=' 90 %
P56524 BXGT011176 Histone deacetylase 4 reviewed Epigenetic regulator HDAC4 Activity '=' 90 %
Q96DB2 BXGT019639 Histone deacetylase 11 reviewed Epigenetic regulator HDAC11 Activity '=' 90 %
Q9BY41 BXGT020180 Histone deacetylase 8 reviewed Epigenetic regulator HDAC8 Activity '=' 90 %
Q8WUI4 BXGT018992 Histone deacetylase 7 reviewed Epigenetic regulator HDAC7 Activity '=' 90 %
Q9UQL6 BXGT021813 Histone deacetylase 5 reviewed Epigenetic regulator HDAC5 Activity '=' 90 %
Q92769 BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 Activity '=' 90 %
Q9UBN7 BXGT021658 Histone deacetylase 6 reviewed Epigenetic regulator HDAC6 Activity '=' 90 %
O15379 BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 Activity '=' 90 %
Q13547 BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 Activity '=' 90 %
Q7ZJM1 BXGT017268 Integrase unreviewed - pol Inhibition '=' 0 %
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 5 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 - - -
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 89125 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00076 Loquat Eriobotrya japonica Fruits
BXGF00087 Sea-buckthornberry Hippophae rhamnoides Fruits
BXGF00585 Vinegar Baking goods
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01357 Ampelopsis japonica Ampelopsis japonica Medicinal Plant
BXGF01426 Cornus officinalis Cornus officinalis Medicinal Plant
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04712 Prunus mume Prunus mume Medicinal Plant
BXGF04889 Pogostemon cablin Pogostemon cablin Medicinal Plant
BXGF04905 Aloe Aloe Medicinal Plant
BXGF04909 Hippophae fructus Hippophae fructus Others
BXGF04926 Aloe africana Aloe africana Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease