Showing entry for 40S ribosomal protein S3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008863
Protein Name40S ribosomal protein S3
Uniport IdP23396
GeneRPS3
Gene Id6188
DomainKH_2; Ribosomal_S3_C
Pfam PF07650   PF00189  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03010 Ribosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0051301 cell division
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0007059 chromosome segregation
Biological Process GO:0042769 DNA damage response, detection of DNA damage
Biological Process GO:0006281 DNA repair
Biological Process GO:0045738 negative regulation of DNA repair
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Biological Process GO:0042104 positive regulation of activated T cell proliferation
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Biological Process GO:1905053 positive regulation of base-excision repair
Biological Process GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
Biological Process GO:1902546 positive regulation of DNA N-glycosylase activity
Biological Process GO:0045739 positive regulation of DNA repair
Biological Process GO:0032079 positive regulation of endodeoxyribonuclease activity
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0032743 positive regulation of interleukin-2 production
Biological Process GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0031116 positive regulation of microtubule polymerization
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:1901224 positive regulation of NIK/NF-kappaB signaling
Biological Process GO:0031334 positive regulation of protein-containing complex assembly
Biological Process GO:0050862 positive regulation of T cell receptor signaling pathway
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0061481 response to TNF agonist
Biological Process GO:0051225 spindle assembly
Biological Process GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Biological Process GO:0006412 translation
Biological Process GO:0006413 translational initiation
Biological Process GO:0019083 viral transcription
molecular function GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
molecular function GO:0003684 damaged DNA binding
molecular function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
molecular function GO:0003677 DNA binding
molecular function GO:0004520 endodeoxyribonuclease activity
molecular function GO:0019899 enzyme binding
molecular function GO:0030544 Hsp70 protein binding
molecular function GO:0051879 Hsp90 protein binding
molecular function GO:0051536 iron-sulfur cluster binding
molecular function GO:0019900 kinase binding
molecular function GO:0008017 microtubule binding
molecular function GO:0003729 mRNA binding
molecular function GO:0032357 oxidized purine DNA binding
molecular function GO:0032358 oxidized pyrimidine DNA binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0051018 protein kinase A binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0003723 RNA binding
molecular function GO:0070181 small ribosomal subunit rRNA binding
molecular function GO:0003735 structural constituent of ribosome
molecular function GO:0097100 supercoiled DNA binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0015631 tubulin binding
molecular function GO:0044390 ubiquitin-like protein conjugating enzyme binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0022627 cytosolic small ribosomal subunit
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0016020 membrane
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0072686 mitotic spindle
cellular component GO:0071159 NF-kappaB complex
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0005844 polysome
cellular component GO:0014069 postsynaptic density
cellular component GO:1990904 ribonucleoprotein complex
cellular component GO:0005840 ribosome
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156842 Eukaryotic Translation Elongation
R-HSA-156902 Peptide chain elongation
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2262752 Cellular responses to stress
R-HSA-2408522 Selenoamino acid metabolism
R-HSA-2408557 Selenocysteine synthesis
R-HSA-376176 Signaling by ROBO receptors
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-5663205 Infectious disease
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-71291 Metabolism of amino acids and derivatives
R-HSA-72312 rRNA processing
R-HSA-72613 Eukaryotic Translation Initiation
R-HSA-72649 Translation initiation complex formation
R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72737 Cap-dependent Translation Initiation
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-72766 Translation
R-HSA-72766 Translation
R-HSA-8868773 rRNA processing in the nucleus and cytosol
R-HSA-8953854 Metabolism of RNA
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-927802 Nonsense-Mediated Decay (NMD)
R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-9675108 Nervous system development
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0022118 BXGD001532 Transient ischemia Pathological Conditions, Signs and Symptoms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0043119 BXGD003029 Werner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0239211 BXGD004972 Oedema auricular Pathological Conditions, Signs and Symptoms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0403824 BXGD008316 Teratozoospermia Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C1257806 BXGD011808 Chromosomal Instability Pathological Conditions, Signs and Symptoms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein