Showing entry for Thymidylate kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008926
Protein NameThymidylate kinase
Uniport IdP23919
GeneDTYMK
Gene Id1841
DomainThymidylate_kin
Pfam PF02223  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0006233 dTDP biosynthetic process
Biological Process GO:0006235 dTTP biosynthetic process
Biological Process GO:0006227 dUDP biosynthetic process
Biological Process GO:0045445 myoblast differentiation
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0046686 response to cadmium ion
Biological Process GO:0043627 response to estrogen
Biological Process GO:0046105 thymidine biosynthetic process
molecular function GO:0005524 ATP binding
molecular function GO:0004550 nucleoside diphosphate kinase activity
molecular function GO:0004798 thymidylate kinase activity
molecular function GO:0009041 uridylate kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005758 mitochondrial intermembrane space
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0013295 BXGD000812 Duodenal Ulcer Digestive System Diseases
C0016085 BXGD001047 Filariasis Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0023904 BXGD001721 Liver Neoplasms, Experimental Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0037354 BXGD002690 Smallpox Infections
C0041296 BXGD002903 Tuberculosis Infections
C0151332 BXGD003415 Active tuberculosis Infections
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0342782 BXGD007549 Depletion of mitochondrial DNA
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0002722 Nitrate 62
BXGC0049801 Thymidine 242.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein