adisease

Showing entry for HIV Infections

General Disease Information
BXGD Id	BXGD001346
Disease Name	HIV Infections
Disease CUI Id	C0019693
MeSH Codes	C01 C20
Disease Class Name	Infections; Immune System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0050117
Disease Ontology Class Name	disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
A1Z1Q3	BXGT001069	ADP-ribose glycohydrolase MACROD2	140733	reviewed
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00299	BXGT003905	Chloride intracellular channel protein 1	1192	reviewed	Ion channel
O00459	BXGT003924	Phosphatidylinositol 3-kinase regulatory subunit beta	5296	reviewed	Enzyme modulator
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14791	BXGT004101	Apolipoprotein L1	8542	reviewed	Transporter
O14931	BXGT004113	Natural cytotoxicity triggering receptor 3	259197	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43813	BXGT004628	Glutathione S-transferase LANCL1	10314	reviewed
O60563	BXGT004883	Cyclin-T1	904	reviewed	Enzyme modulator
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O75385	BXGT005121	Serine/threonine-protein kinase ULK1	8408	reviewed	Kinase
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
O95864	BXGT005403	Acyl-CoA 6-desaturase	9415	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00751	BXGT005643	Complement factor B	629	reviewed
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01730	BXGT005781	T-cell surface glycoprotein CD4	920	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02818	BXGT005969	Osteocalcin	632	reviewed
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04183	BXGT006166	Thymidine kinase, cytosolic	7083	reviewed	Kinase
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05543	BXGT006366	Thyroxine-binding globulin	6906	reviewed	Enzyme modulator
P06126	BXGT006412	T-cell surface glycoprotein CD1a	909	reviewed
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06239	BXGT006427	Tyrosine-protein kinase Lck	3932	reviewed	Kinase
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06493	BXGT006445	Cyclin-dependent kinase 1	983	reviewed	Kinase
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06734	BXGT006491	Low affinity immunoglobulin epsilon Fc receptor	2208	reviewed	Receptor
P06746	BXGT006496	DNA polymerase beta	5423	reviewed	Enzyme
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07602	BXGT006646	Prosaposin	5660	reviewed
P07686	BXGT006657	Beta-hexosaminidase subunit beta	3074	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P07948	BXGT006702	Tyrosine-protein kinase Lyn	4067	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08238	BXGT006753	Heat shock protein HSP 90-beta	3326	reviewed	Chaperone
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08670	BXGT006810	Vimentin	7431	reviewed
P08684	BXGT006812	Cytochrome P450 3A4	1576	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08865	BXGT006832	40S ribosomal protein SA	3921	reviewed	Nucleic acid binding
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09960	BXGT006952	Leukotriene A-4 hydrolase	4048	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10619	BXGT007589	Lysosomal protective protein	5476	reviewed	Enzyme
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11233	BXGT007678	Ras-related protein Ral-A	5898	reviewed	Enzyme modulator
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11717	BXGT007740	Cation-independent mannose-6-phosphate receptor	3482	reviewed	Receptor
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13051	BXGT007877	Uracil-DNA glycosylase	7374	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13489	BXGT007913	Ribonuclease inhibitor	6050	reviewed	Transcription factor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14151	BXGT007990	L-selectin	6402	reviewed
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15104	BXGT008081	Glutamine synthetase	2752	reviewed	Enzyme
P15151	BXGT008089	Poliovirus receptor	5817	reviewed
P15309	BXGT008105	Prostatic acid phosphatase	55	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16109	BXGT008194	P-selectin	6403	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P17980	BXGT008362	26S proteasome regulatory subunit 6A	5702	reviewed	Enzyme
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19525	BXGT008492	Interferon-induced, double-stranded RNA-activated protein kinase	5610	reviewed	Kinase
P20338	BXGT008564	Ras-related protein Rab-4A	5867	reviewed
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P20702	BXGT008592	Integrin alpha-X	3687	reviewed
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21333	BXGT008638	Filamin-A	2316	reviewed
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22087	BXGT008729	rRNA 2'-O-methyltransferase fibrillarin	2091	reviewed	Enzyme
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22352	BXGT008758	Glutathione peroxidase 3	2878	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23246	BXGT008840	Splicing factor, proline- and glutamine-rich	6421	reviewed	Nucleic acid binding
P23284	BXGT008845	Peptidyl-prolyl cis-trans isomerase B	5479	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23443	BXGT008866	Ribosomal protein S6 kinase beta-1	6198	reviewed	Kinase
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23919	BXGT008926	Thymidylate kinase	1841	reviewed	Kinase
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25024	BXGT009005	C-X-C chemokine receptor type 1	3577	reviewed	G-protein coupled receptor
P25100	BXGT009017	Alpha-1D adrenergic receptor	146	reviewed	G-protein coupled receptor
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P25789	BXGT009071	Proteasome subunit alpha type-4	5685	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28066	BXGT009227	Proteasome subunit alpha type-5	5686	reviewed
P28070	BXGT009230	Proteasome subunit beta type-4	5692	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29017	BXGT009305	T-cell surface glycoprotein CD1c	911	reviewed
P29074	BXGT009313	Tyrosine-protein phosphatase non-receptor type 4	5775	reviewed
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30291	BXGT009417	Wee1-like protein kinase	7465	reviewed	Kinase
P30305	BXGT009419	M-phase inducer phosphatase 2	994	reviewed	Enzyme
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	7433	reviewed	G-protein coupled receptor
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36544	BXGT009926	Neuronal acetylcholine receptor subunit alpha-7	89832	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41273	BXGT010251	Tumor necrosis factor ligand superfamily member 9	8744	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43487	BXGT010393	Ran-specific GTPase-activating protein	5902	reviewed	Enzyme modulator
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48549	BXGT010644	G protein-activated inward rectifier potassium channel 1	3760	reviewed	Ion channel
P48643	BXGT010650	T-complex protein 1 subunit epsilon	22948	reviewed	Chaperone
P49137	BXGT010680	MAP kinase-activated protein kinase 2	9261	reviewed	Kinase
P49368	BXGT010701	T-complex protein 1 subunit gamma	7203	reviewed	Chaperone
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51665	BXGT010874	26S proteasome non-ATPase regulatory subunit 7	5713	reviewed	Enzyme
P51677	BXGT010876	C-C chemokine receptor type 3	1232	reviewed	G-protein coupled receptor
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P51858	BXGT010900	Hepatoma-derived growth factor	3068	reviewed	Signaling
P52565	BXGT010933	Rho GDP-dissociation inhibitor 1	396	reviewed	Enzyme modulator
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P54577	BXGT011055	Tyrosine--tRNA ligase, cytoplasmic	8565	reviewed	Enzyme
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P54829	BXGT011085	Tyrosine-protein phosphatase non-receptor type 5	84867	reviewed
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P56537	BXGT011177	Eukaryotic translation initiation factor 6	3692	reviewed	Nucleic acid binding
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60842	BXGT011330	Eukaryotic initiation factor 4A-I	1973	reviewed
P60900	BXGT011338	Proteasome subunit alpha type-6	5687	reviewed
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61626	BXGT011382	Lysozyme C	4069	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P62318	BXGT011422	Small nuclear ribonucleoprotein Sm D3	6634	reviewed	Nucleic acid binding
P62826	BXGT011463	GTP-binding nuclear protein Ran	5901	reviewed	Enzyme modulator
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P62993	BXGT011480	Growth factor receptor-bound protein 2	2885	reviewed
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P81172	BXGT011935	Hepcidin	57817	reviewed
Q00613	BXGT012540	Heat shock factor protein 1	3297	reviewed	Transcription factor
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01081	BXGT012566	Splicing factor U2AF 35 kDa subunit	7307	reviewed
Q01523	BXGT012594	Defensin-5	1670	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q02880	BXGT012677	DNA topoisomerase 2-beta	7155	reviewed
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q06323	BXGT012873	Proteasome activator complex subunit 1	5720	reviewed
Q07011	BXGT012912	Tumor necrosis factor receptor superfamily member 9	3604	reviewed
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q07955	BXGT012951	Serine/arginine-rich splicing factor 1	6426	reviewed	Nucleic acid binding
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q08881	BXGT013012	Tyrosine-protein kinase ITK/TSK	3702	reviewed	Kinase
Q09028	BXGT013025	Histone-binding protein RBBP4	5928	reviewed
Q10589	BXGT013203	Bone marrow stromal antigen 2	684	reviewed
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	3757	reviewed	Ion channel
Q12874	BXGT013274	Splicing factor 3A subunit 3	10946	reviewed	Nucleic acid binding
Q12918	BXGT013280	Killer cell lectin-like receptor subfamily B member 1	3820	reviewed
Q13093	BXGT013310	Platelet-activating factor acetylhydrolase	7941	reviewed	Enzyme
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13177	BXGT013323	Serine/threonine-protein kinase PAK 2	5062	reviewed	Kinase
Q13219	BXGT013327	Pappalysin-1	5069	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13541	BXGT013371	Eukaryotic translation initiation factor 4E-binding protein 1	1978	reviewed	Nucleic acid binding
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q13637	BXGT013388	Ras-related protein Rab-32	10981	reviewed
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14624	BXGT013491	Inter-alpha-trypsin inhibitor heavy chain H4	3700	reviewed	Enzyme modulator
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14974	BXGT013516	Importin subunit beta-1	3837	reviewed	Transporter
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15413	BXGT013568	Ryanodine receptor 3	6263	reviewed	Ion channel
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q15843	BXGT013608	NEDD8	4738	reviewed	Nucleic acid binding
Q15907	BXGT013611	Ras-related protein Rab-11B	9230	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16512	BXGT013631	Serine/threonine-protein kinase N1	5585	reviewed	Kinase
Q16584	BXGT013642	Mitogen-activated protein kinase kinase kinase 11	4296	reviewed	Kinase
Q16666	BXGT013654	Gamma-interferon-inducible protein 16	3428	reviewed	Transcription factor
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q495A1	BXGT014764	T-cell immunoreceptor with Ig and ITIM domains	201633	reviewed
Q5D1E8	BXGT015318	Endoribonuclease ZC3H12A	80149	reviewed	Nucleic acid binding
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6GTX8	BXGT016315	Leukocyte-associated immunoglobulin-like receptor 1	3903	reviewed	Receptor
Q6P179	BXGT016440	Endoplasmic reticulum aminopeptidase 2	64167	reviewed	Enzyme
Q6P2Q9	BXGT016446	Pre-mRNA-processing-splicing factor 8	10594	reviewed	Nucleic acid binding
Q76LX8	BXGT016870	A disintegrin and metalloproteinase with thrombospondin motifs 13	11093	reviewed	Enzyme
Q7Z7C8	BXGT017261	Transcription initiation factor TFIID subunit 8	129685	reviewed
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q8IUX4	BXGT018337	DNA dC->dU-editing enzyme APOBEC-3F	200316	reviewed	Enzyme
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8N5Z0	BXGT018521	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	51166	reviewed	Enzyme
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92598	BXGT019356	Heat shock protein 105 kDa	10808	reviewed
Q92934	BXGT019396	Bcl2-associated agonist of cell death	572	reviewed
Q92979	BXGT019402	Ribosomal RNA small subunit methyltransferase NEP1	10436	reviewed	Nucleic acid binding
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96DU3	BXGT019643	SLAM family member 6	114836	reviewed	Enzyme
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96FI4	BXGT019658	Endonuclease 8-like 1	79661	reviewed
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q96LA8	BXGT019691	Protein arginine N-methyltransferase 6	55170	reviewed	Epigenetic regulator
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99496	BXGT019925	E3 ubiquitin-protein ligase RING2	6045	reviewed
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q99816	BXGT019966	Tumor susceptibility gene 101 protein	7251	reviewed	Enzyme
Q9BV57	BXGT020140	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	55256	reviewed	Enzyme
Q9BWP8	BXGT020153	Collectin-11	78989	reviewed	Surfactant
Q9BY32	BXGT020179	Inosine triphosphate pyrophosphatase	3704	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9H2X3	BXGT020457	C-type lectin domain family 4 member M	10332	reviewed	Receptor
Q9H2X6	BXGT020458	Homeodomain-interacting protein kinase 2	28996	reviewed	Kinase
Q9H816	BXGT020494	5' exonuclease Apollo	64858	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HC16	BXGT020525	DNA dC->dU-editing enzyme APOBEC-3G	60489	reviewed	Enzyme
Q9NNX6	BXGT021140	CD209 antigen	30835	reviewed	Receptor
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NR97	BXGT021182	Toll-like receptor 8	51311	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P2K8	BXGT021302	eIF-2-alpha kinase GCN2	440275	reviewed
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9UH17	BXGT021691	DNA dC->dU-editing enzyme APOBEC-3B	9582	reviewed	Enzyme
Q9UH99	BXGT021693	SUN domain-containing protein 2	25777	reviewed	Cellular structure
Q9UJ71	BXGT021725	C-type lectin domain family 4 member K	50489	reviewed	Receptor
Q9UKA9	BXGT021740	Polypyrimidine tract-binding protein 2	58155	reviewed
Q9ULY5	BXGT021770	C-type lectin domain family 4 member E	26253	reviewed	Receptor
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
Q9Y618	BXGT022315	Nuclear receptor corepressor 2	9612	reviewed	Transcription factor
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q7Z3S7	BXGT022658	Voltage-dependent calcium channel subunit alpha-2/delta-4	93589	reviewed	Ion channel
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q9UM82	BXGT023181	Spermatogenesis-associated protein 2	9825	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
P07766	BXGT023327	T-cell surface glycoprotein CD3 epsilon chain	916	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P16615	BXGT023653	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	488	reviewed	Transporter
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q13007	BXGT023883	Interleukin-24	11009	reviewed
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
P29590	BXGT024350	Protein PML	5371	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
P21926	BXGT024578	CD9 antigen	928	reviewed
Q14997	BXGT024710	Proteasome activator complex subunit 4	23198	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P38646	BXGT024954	Stress-70 protein, mitochondrial	3313	reviewed
Q7Z6A9	BXGT025024	B- and T-lymphocyte attenuator	151888	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q8IUN9	BXGT025263	C-type lectin domain family 10 member A	10462	reviewed	Receptor
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}