Showing entry for Immunoglobulin alpha Fc receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008945
Protein NameImmunoglobulin alpha Fc receptor
Uniport IdP24071
GeneFCAR
Gene Id2204
Domain-
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05150 Staphylococcus aureus infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
Biological Process GO:0035457 cellular response to interferon-alpha
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0071354 cellular response to interleukin-6
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0038093 Fc receptor signaling pathway
Biological Process GO:0006955 immune response
Biological Process GO:0042119 neutrophil activation
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0002446 neutrophil mediated immunity
Biological Process GO:0033031 positive regulation of neutrophil apoptotic process
Biological Process GO:1903209 positive regulation of oxidative stress-induced cell death
molecular function GO:0019862 IgA binding
molecular function GO:0019766 IgA receptor activity
cellular component GO:0005576 extracellular region
cellular component GO:0101003 ficolin-1-rich granule membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0035579 specific granule membrane
cellular component GO:0070821 tertiary granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001342 BXGD000042 Acute periodontitis Stomatognathic Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011608 BXGD000736 Dermatitis Herpetiformis Skin and Connective Tissue Diseases; Immune System Diseases
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0031106 BXGD002283 Aggressive Periodontitis Stomatognathic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263313 BXGD005285 Pemphigus Foliaceus Skin and Connective Tissue Diseases; Immune System Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0339901 BXGD007289 Acute respiratory infections Infections; Respiratory Tract Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0744471 BXGD010098 Gram-negative bacteremia Pathological Conditions, Signs and Symptoms; Infections
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3161650 BXGD018513 Primary immunoglobulin A nephropathy (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C3714514 BXGD019409 Infection Infections
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein