Showing entry for Dual specificity protein phosphatase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009271
Protein NameDual specificity protein phosphatase 1
Uniport IdP28563
GeneDusp1
Gene Id19252
DomainDSPc; Rhodanese
Pfam PF00782   PF00581  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990869 cellular response to chemokine
Biological Process GO:0032870 cellular response to hormone stimulus
Biological Process GO:0001706 endoderm formation
Biological Process GO:0000188 inactivation of MAPK activity
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0071850 mitotic cell cycle arrest
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0007162 negative regulation of cell adhesion
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:2000279 negative regulation of DNA biosynthetic process
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0043409 negative regulation of MAPK cascade
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:0051447 negative regulation of meiotic cell cycle
Biological Process GO:0090027 negative regulation of monocyte chemotaxis
Biological Process GO:1903753 negative regulation of p38MAPK cascade
Biological Process GO:0070262 peptidyl-serine dephosphorylation
Biological Process GO:0035970 peptidyl-threonine dephosphorylation
Biological Process GO:0035335 peptidyl-tyrosine dephosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0051591 response to cAMP
Biological Process GO:0032355 response to estradiol
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0009416 response to light stimulus
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0033574 response to testosterone
molecular function GO:0019838 growth factor binding
molecular function GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity
molecular function GO:0051019 mitogen-activated protein kinase binding
molecular function GO:0004721 phosphoprotein phosphatase activity
molecular function GO:0004722 protein serine/threonine phosphatase activity
molecular function GO:0008138 protein tyrosine/serine/threonine phosphatase activity
molecular function GO:0008330 protein tyrosine/threonine phosphatase activity
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0001991 Juglone 174.15
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0025204 Anthraquinone 208.05
BXGC0044200 Menadione 172.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein