Showing entry for Anthraquinone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0025204
Compound NameAnthraquinone
Structure
FormulaC14H8O2
InchiKeyRZVHIXYEVGDQDX-UHFFFAOYSA-N
SMILESO=C1c2ccccc2C(=O)c2c1cccc2
InchiInChI=1S/C14H8O2/c15-13-9-5-1-2-6-10(9)14(16)12-8-4-3-7-11(12)13/h1-8H
IUPACanthracene-9,10-dione
Molecular Weight208.05
Pubchem Id6780
Chembl IdCHEMBL55659
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50094892
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009419 M-phase inducer phosphatase 2 reviewed Enzyme CDC25B - 9510 - -
reviewed BXGT009271 Dual specificity protein phosphatase 1 reviewed Dusp1 - >50000 - -
reviewed BXGT016113 Dual specificity protein phosphatase 6 reviewed Dusp6 - >50000 - -
CHEMBL CHEMBL55659
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 114 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 114 %
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 0 pm/min/mg
Q64346 BXGT016113 Dual specificity protein phosphatase 6 reviewed - Dusp6 IC50 '>' 50000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 17782 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '>' 1000000 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '>' 1000000 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '>' 1000000 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '>' 1000000 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '>' 1000000 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '>' 1000000 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '>' 1000000 nM
P19793 BXGT008515 Retinoic acid receptor RXR-alpha reviewed Nuclear receptor RXRA Potency - 35481 nM
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 reviewed Epigenetic regulator EHMT1 Inhibition - - -
P30305 BXGT009419 M-phase inducer phosphatase 2 reviewed Enzyme CDC25B IC50 '=' 9510 nM
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 3219 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 112 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 112 %
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 96 %
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 35481 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 109 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 109 %
P28563 BXGT009271 Dual specificity protein phosphatase 1 reviewed - Dusp1 IC50 '>' 50000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 27306 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 28183 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 28183 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 4327 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Inhibition - - -
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Inhibition '=' 20 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 78 %
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 IC50 '>' 100000 nM
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 reviewed Epigenetic regulator EHMT1 Inhibition '=' 20 %
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 reviewed Epigenetic regulator EHMT1 IC50 '>' 100000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00981 Flacourtia jangomas Flacourtia jangomas Medicinal Plant
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01187 Onobrychis arenaria Onobrychis arenaria Others
BXGF01223 Eria mollis Eria mollis Others
BXGF01302 Dysoxylum cumingianum Dysoxylum cumingianum Others
BXGF01307 Hemerocallis radix Hemerocallis radix Others
BXGF01344 Psychotria stachyoides Psychotria stachyoides Others
BXGF01391 Dodonaea viscosa Dodonaea viscosa Medicinal Plant
BXGF01568 Teucrium yemense Teucrium yemense Others
BXGF01641 Neobalanocarpus heimii Neobalanocarpus heimii Others
BXGF01683 Aconitum tasiromontanum Aconitum tasiromontanum Others
BXGF01764 Dendriopoterium menendezii Dendriopoterium menendezii Others
BXGF01794 Adansonia grandidieri Adansonia grandidieri Human Edible Plant
BXGF01812 Physalis alkekengi Physalis alkekengi Medicinal Plant
BXGF01836 Aphyllocladus denticulatus Aphyllocladus denticulatus Others
BXGF01850 Bassia muricata Bassia muricata Medicinal Plant
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF01947 Senecio subdentatus Senecio subdentatus Others
BXGF02006 Aconitum seravschanicum Aconitum seravschanicum Others
BXGF02204 Apocynum venetum Apocynum venetum Medicinal Plant
BXGF03158 Rheum officinale Rheum officinale Medicinal Plant
BXGF03485 Justicia secunda Justicia secunda Others
BXGF03837 Casearia membranacea Casearia membranacea Medicinal Plant
BXGF03988 Rheum coreanum Rheum coreanum Others
BXGF04205 Aster sedifolius Aster sedifolius Others
BXGF04539 Rheum palmatum Rheum palmatum Medicinal Plant
BXGF04573 Rubia akane Rubia akane Medicinal Plant
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04881 Fallopia multiflora Fallopia multiflora Medicinal Plant
BXGF04917 Cassia obtusifolia Cassia obtusifolia Medicinal Plant
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF04976 Arachniodes exilis Arachniodes exilis Medicinal Plant
BXGF05018 Lavandula vera Lavandula vera Medicinal Plant
BXGF05877 Rheum tanguticum Rheum tanguticum Medicinal Plant
BXGF05886 Senna tora Senna tora Medicinal Plant
BXGF06011 Enceliopsis argophylla Enceliopsis argophylla Others
BXGF06095 Rheum undulatum Rheum undulatum Medicinal Plant
BXGF06114 Senna obtusifolia Senna obtusifolia Medicinal Plant
BXGF06281 Miliusa velutina Miliusa velutina Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease