Showing entry for Adenylosuccinate synthetase isozyme 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009430
Protein NameAdenylosuccinate synthetase isozyme 2
Uniport IdP30520
GeneADSS2
Gene Id159
DomainAdenylsucc_synt
Pfam PF00709  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0044208 'de novo' AMP biosynthetic process
Biological Process GO:0006167 AMP biosynthetic process
Biological Process GO:0006531 aspartate metabolic process
Biological Process GO:0071257 cellular response to electrical stimulus
Biological Process GO:0002376 immune system process
Biological Process GO:0046040 IMP metabolic process
Biological Process GO:0009168 purine ribonucleoside monophosphate biosynthetic process
Biological Process GO:0060359 response to ammonium ion
Biological Process GO:0014074 response to purine-containing compound
molecular function GO:0004019 adenylosuccinate synthase activity
molecular function GO:0005525 GTP binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0042301 phosphate ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005739 mitochondrion
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-73817 Purine ribonucleoside monophosphate biosynthesis
R-HSA-8956320 Nucleobase biosynthesis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0153519 BXGD003660 Malignant neoplasm of connective and other soft tissue, site unspecified Neoplasms
C0936250 BXGD011481 Eczema Herpeticum Infections; Skin and Connective Tissue Diseases
C1629609 BXGD013479 Age at menopause
C1853193 BXGD015312 Recurrent skin infections Infections; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006186 L-Aspartic acid 133.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein