adisease

Showing entry for Eczema

General Disease Information
BXGD Id	BXGD000858
Disease Name	Eczema
Disease CUI Id	C0013595
MeSH Codes	C17
Disease Class Name	Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001574 HP:0002715
Human Phenotype Ontology Term	Abnormality of the integument; Abnormality of the immune system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00167	BXGT003887	Eyes absent homolog 2	2139	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00401	BXGT003915	Neural Wiskott-Aldrich syndrome protein	8976	reviewed	Cellular structure
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15146	BXGT004131	Muscle, skeletal receptor tyrosine-protein kinase	4593	reviewed	Kinase
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
O43813	BXGT004628	Glutathione S-transferase LANCL1	10314	reviewed
O60427	BXGT004875	Acyl-CoA (8-3)-desaturase	3992	reviewed
O60486	BXGT004877	Plexin-C1	10154	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60656	BXGT004889	UDP-glucuronosyltransferase 1-9	54600	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O60911	BXGT004909	Cathepsin L2	1515	reviewed	Enzyme
O75347	BXGT005113	Tubulin-specific chaperone A	6902	reviewed	Chaperone
O75362	BXGT005114	Zinc finger protein 217	7764	reviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	8989	reviewed	Ion channel
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
O95718	BXGT005392	Steroid hormone receptor ERR2	2103	reviewed	Nuclear receptor
O95835	BXGT005400	Serine/threonine-protein kinase LATS1	9113	reviewed	Kinase
O95864	BXGT005403	Acyl-CoA 6-desaturase	9415	reviewed
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01591	BXGT005774	Immunoglobulin J chain	3512	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02654	BXGT005911	Apolipoprotein C-I	341	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02760	BXGT005948	Protein AMBP	259	reviewed
P02763	BXGT005951	Alpha-1-acid glycoprotein 1	5004	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02775	BXGT005960	Platelet basic protein	5473	reviewed	Signaling
P02788	BXGT005963	Lactotransferrin	4057	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04264	BXGT006176	Keratin, type II cytoskeletal 1	3848	reviewed
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P06126	BXGT006412	T-cell surface glycoprotein CD1a	909	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06734	BXGT006491	Low affinity immunoglobulin epsilon Fc receptor	2208	reviewed	Receptor
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08133	BXGT006727	Annexin A6	309	reviewed
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08779	BXGT006824	Keratin, type I cytoskeletal 16	3868	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08865	BXGT006832	40S ribosomal protein SA	3921	reviewed	Nucleic acid binding
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09668	BXGT006914	Pro-cathepsin H	1512	reviewed	Enzyme
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10153	BXGT007544	Non-secretory ribonuclease	6036	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11168	BXGT007663	Solute carrier family 2, facilitated glucose transporter member 2	6514	reviewed	Transporter
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11586	BXGT007723	C-1-tetrahydrofolate synthase, cytoplasmic	4522	reviewed	Enzyme
P12319	BXGT007800	High affinity immunoglobulin epsilon receptor subunit alpha	2205	reviewed	Cell adhesion
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P12830	BXGT007852	Cadherin-1	999	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16109	BXGT008194	P-selectin	6403	reviewed
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16581	BXGT008245	E-selectin	6401	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20061	BXGT008542	Transcobalamin-1	6947	reviewed
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23468	BXGT008870	Receptor-type tyrosine-protein phosphatase delta	5789	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P25311	BXGT009036	Zinc-alpha-2-glycoprotein	563	reviewed
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28562	BXGT009270	Dual specificity protein phosphatase 1	1843	reviewed
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29017	BXGT009305	T-cell surface glycoprotein CD1c	911	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29350	BXGT009335	Tyrosine-protein phosphatase non-receptor type 6	5777	reviewed
P29373	BXGT009337	Cellular retinoic acid-binding protein 2	1382	reviewed
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29508	BXGT009358	Serpin B3	6317	reviewed	Enzyme modulator
P29597	BXGT009367	Non-receptor tyrosine-protein kinase TYK2	7297	reviewed	Kinase
P30520	BXGT009430	Adenylosuccinate synthetase isozyme 2	159	reviewed	Enzyme
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30989	BXGT009492	Neurotensin receptor type 1	4923	reviewed	G-protein coupled receptor
P31151	BXGT009510	Protein S100-A7	6278	reviewed	Calcium-binding protein
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P34130	BXGT009752	Neurotrophin-4	4909	reviewed	Signaling
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35030	BXGT009784	Trypsin-3	5646	reviewed	Enzyme
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35527	BXGT009843	Keratin, type I cytoskeletal 9	3857	reviewed
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35916	BXGT009881	Vascular endothelial growth factor receptor 3	2324	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46940	BXGT010556	Ras GTPase-activating-like protein IQGAP1	8826	reviewed	Enzyme modulator
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49862	BXGT010752	Kallikrein-7	5650	reviewed	Enzyme
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50120	BXGT010773	Retinol-binding protein 2	5948	reviewed
P50135	BXGT010776	Histamine N-methyltransferase	3176	reviewed
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51665	BXGT010874	26S proteasome non-ATPase regulatory subunit 7	5713	reviewed	Enzyme
P51677	BXGT010876	C-C chemokine receptor type 3	1232	reviewed	G-protein coupled receptor
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P51687	BXGT010882	Sulfite oxidase, mitochondrial	6821	reviewed
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P51813	BXGT010894	Cytoplasmic tyrosine-protein kinase BMX	660	reviewed	Kinase
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P68371	BXGT011597	Tubulin beta-4B chain	10383	reviewed	Cellular structure
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q01344	BXGT012585	Interleukin-5 receptor subunit alpha	3568	reviewed	Signaling
Q01970	BXGT012627	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	5331	reviewed	Enzyme
Q02083	BXGT012633	N-acylethanolamine-hydrolyzing acid amidase	27163	reviewed	Enzyme
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	5142	reviewed
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q08174	BXGT012963	Protocadherin-1	5097	reviewed
Q08188	BXGT012965	Protein-glutamine gamma-glutamyltransferase E	7053	reviewed	Enzyme
Q08334	BXGT012981	Interleukin-10 receptor subunit beta	3588	reviewed	Receptor
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q08554	BXGT012990	Desmocollin-1	1823	reviewed	Cell adhesion
Q08881	BXGT013012	Tyrosine-protein kinase ITK/TSK	3702	reviewed	Kinase
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q13093	BXGT013310	Platelet-activating factor acetylhydrolase	7941	reviewed	Enzyme
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13636	BXGT013387	Ras-related protein Rab-31	11031	reviewed
Q13946	BXGT013406	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	5150	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14392	BXGT013465	Transforming growth factor beta activator LRRC32	2615	reviewed	Receptor
Q14573	BXGT013486	Inositol 1,4,5-trisphosphate receptor type 3	3710	reviewed	Ion channel
Q14627	BXGT013492	Interleukin-13 receptor subunit alpha-2	3598	reviewed	Signaling
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15080	BXGT013535	Neutrophil cytosol factor 4	4689	reviewed
Q15262	BXGT013555	Receptor-type tyrosine-protein phosphatase kappa	5796	reviewed	Enzyme
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16348	BXGT013627	Solute carrier family 15 member 2	6565	reviewed	Transporter
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16548	BXGT013636	Bcl-2-related protein A1	597	reviewed	Signaling
Q16549	BXGT013637	Proprotein convertase subtilisin/kexin type 7	9159	reviewed
Q16719	BXGT013662	Kynureninase	8942	reviewed	Enzyme
Q16769	BXGT013665	Glutaminyl-peptide cyclotransferase	25797	reviewed	Enzyme
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6P179	BXGT016440	Endoplasmic reticulum aminopeptidase 2	64167	reviewed	Enzyme
Q6VVX0	BXGT016585	Vitamin D 25-hydroxylase	120227	reviewed
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q7Z2W7	BXGT017248	Transient receptor potential cation channel subfamily M member 8	79054	reviewed	Ion channel
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q86YZ3	BXGT017637	Hornerin	388697	reviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8WWA0	BXGT018999	Intelectin-1	55600	reviewed
Q92835	BXGT019382	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	3635	reviewed
Q92876	BXGT019388	Kallikrein-6	5653	reviewed	Enzyme
Q92945	BXGT019397	Far upstream element-binding protein 2	8570	reviewed	Enzyme
Q92956	BXGT019399	Tumor necrosis factor receptor superfamily member 14	8764	reviewed
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96C19	BXGT019630	EF-hand domain-containing protein D2	79180	reviewed	Calcium-binding protein
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96ES7	BXGT019654	SAGA-associated factor 29	112869	reviewed
Q96H15	BXGT019669	T-cell immunoglobulin and mucin domain-containing protein 4	91937	reviewed
Q96MG7	BXGT019696	Non-structural maintenance of chromosomes element 3 homolog	56160	reviewed	Cell adhesion
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99581	BXGT019937	Protein FEV	54738	reviewed	Transcription factor
Q99685	BXGT019948	Monoglyceride lipase	11343	reviewed	Enzyme
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q99959	BXGT019977	Plakophilin-2	5318	reviewed	Cellular structure
Q9BQE4	BXGT020110	Selenoprotein S	55829	reviewed
Q9BS40	BXGT020121	Latexin	56925	reviewed
Q9BXD5	BXGT020166	N-acetylneuraminate lyase	80896	reviewed	Enzyme
Q9BXL7	BXGT020171	Caspase recruitment domain-containing protein 11	84433	reviewed
Q9BZ11	BXGT020193	Disintegrin and metalloproteinase domain-containing protein 33	80332	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9GZT4	BXGT020424	Serine racemase	63826	reviewed	Enzyme
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9GZZ9	BXGT020430	Ubiquitin-like modifier-activating enzyme 5	79876	reviewed	Enzyme
Q9H2J7	BXGT020453	Sodium-dependent neutral amino acid transporter B(0)AT2	55117	reviewed	Transporter
Q9H3N8	BXGT020463	Histamine H4 receptor	59340	reviewed	G-protein coupled receptor
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZ42	BXGT021268	Gamma-secretase subunit PEN-2	55851	reviewed
Q9NZK7	BXGT021276	Group IIE secretory phospholipase A2	30814	reviewed	Enzyme
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UEW3	BXGT021674	Macrophage receptor MARCO	8685	reviewed
Q9UJ71	BXGT021725	C-type lectin domain family 4 member K	50489	reviewed	Receptor
Q9UJV9	BXGT021731	Probable ATP-dependent RNA helicase DDX41	51428	reviewed
Q9UMF0	BXGT021774	Intercellular adhesion molecule 5	7087	reviewed
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UNA4	BXGT021785	DNA polymerase iota	11201	reviewed
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	10800	reviewed	G-protein coupled receptor
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
Q9Y2K2	BXGT022238	Serine/threonine-protein kinase SIK3	23387	reviewed	Kinase
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y616	BXGT022313	Interleukin-1 receptor-associated kinase 3	11213	reviewed	Kinase
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q92482	BXGT022676	Aquaporin-3	360	reviewed	Ion channel
Q86US8	BXGT022850	Telomerase-binding protein EST1A	23293	reviewed
Q9UNS1	BXGT022882	Protein timeless homolog	8914	reviewed
Q92878	BXGT023071	DNA repair protein RAD50	10111	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
Q6GQQ9	BXGT023186	OTU domain-containing protein 7B	56957	reviewed	Enzyme
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
O14490	BXGT023570	Disks large-associated protein 1	9229	reviewed	Receptor
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
Q5T2W1	BXGT023979	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	5174	reviewed
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q99435	BXGT025240	Protein kinase C-binding protein NELL2	4753	reviewed	Calcium-binding protein
Q8IUN9	BXGT025263	C-type lectin domain family 10 member A	10462	reviewed	Receptor
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
Q9UK61	BXGT025658	Protein TASOR	23272	reviewed
Q96LR5	BXGT025885	Ubiquitin-conjugating enzyme E2 E2	7325	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P21731	BXGT026174	Thromboxane A2 receptor	6915	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}