Showing entry for Guanine nucleotide-binding protein subunit alpha-15


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009457
Protein NameGuanine nucleotide-binding protein subunit alpha-15
Uniport IdP30679
GeneGNA15
Gene Id2769
DomainG-alpha
Pfam PF00503  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001508 action potential
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
Biological Process GO:0007207 phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0030168 platelet activation
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
molecular function GO:0031683 G-protein beta/gamma-subunit complex binding
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0031826 type 2A serotonin receptor binding
cellular component GO:0005834 heterotrimeric G-protein complex
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-109582 Hemostasis
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-163685 Integration of energy metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-372790 Signaling by GPCR
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-388396 GPCR downstream signalling
R-HSA-392518 Signal amplification
R-HSA-392518 Signal amplification
R-HSA-399997 Acetylcholine regulates insulin secretion
R-HSA-399997 Acetylcholine regulates insulin secretion
R-HSA-400451 Free fatty acids regulate insulin secretion
R-HSA-400451 Free fatty acids regulate insulin secretion
R-HSA-416476 G alpha (q) signalling events
R-HSA-416476 G alpha (q) signalling events
R-HSA-418592 ADP signalling through P2Y purinoceptor 1
R-HSA-418592 ADP signalling through P2Y purinoceptor 1
R-HSA-422356 Regulation of insulin secretion
R-HSA-422356 Regulation of insulin secretion
R-HSA-428930 Thromboxane signalling through TP receptor
R-HSA-434316 Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
R-HSA-434316 Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76002 Platelet activation, signaling and aggregation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032131 BXGD002330 Plasmacytoma Neoplasms; Immune System Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0456861 BXGD008878 Low grade B-cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0004757 2-Aminoacetophenone 135.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein