Showing entry for Tyrosine-protein phosphatase non-receptor type 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009871
Protein NameTyrosine-protein phosphatase non-receptor type 1
Uniport IdP35821
GenePtpn1
Gene Id19246
DomainY_phosphatase
Pfam PF00102  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031532 actin cytoskeleton reorganization
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:0036498 IRE1-mediated unfolded protein response
Biological Process GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:1903898 negative regulation of PERK-mediated unfolded protein response
Biological Process GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
Biological Process GO:0035335 peptidyl-tyrosine dephosphorylation
Biological Process GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
Biological Process GO:0035791 platelet-derived growth factor receptor-beta signaling pathway
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:2000646 positive regulation of receptor catabolic process
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0030100 regulation of endocytosis
Biological Process GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway
Biological Process GO:0046626 regulation of insulin receptor signaling pathway
Biological Process GO:0033157 regulation of intracellular protein transport
Biological Process GO:0009966 regulation of signal transduction
Biological Process GO:0034976 response to endoplasmic reticulum stress
molecular function GO:0019899 enzyme binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0005158 insulin receptor binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0051721 protein phosphatase 2A binding
molecular function GO:0004725 protein tyrosine phosphatase activity
molecular function GO:0030971 receptor tyrosine kinase binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0098554 cytoplasmic side of endoplasmic reticulum membrane
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0030061 mitochondrial crista
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0097443 sorting endosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002064 Amentoflavone 538.46
BXGC0010010 3,8''-Biapigenin 538.46
BXGC0013850 Robustaflavone 538.09
BXGC0029484 Cupressuflavone 538.09
BXGC0039079 Taiwaniaflavone 538.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein