acompound

Showing entry for Cupressuflavone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0029484
Compound Name	Cupressuflavone
Structure
Formula	C30H18O10
InchiKey	LADPNODMUXOPRG-UHFFFAOYSA-N
SMILES	Oc1ccc(cc1)c1cc(=O)c2c(o1)c(c(cc2O)O)c1c(O)cc(c2c1oc(cc2=O)c1ccc(cc1)O)O
Inchi	InChI=1S/C30H18O10/c31-15-5-1-13(2-6-15)23-11-21(37)25-17(33)9-19(35)27(29(25)39-23)28-20(36)10-18(34)26-22(38)12-24(40-30(26)28)14-3-7-16(32)8-4-14/h1-12,31-36H
IUPAC	8-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Molecular Weight	538.09
Pubchem Id	5281609
Chembl Id	CHEMBL1208973

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	-	>10000	-	-
reviewed	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed		PTPN1	10700	-	-	-
reviewed	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed		PTPN1	-	9600	-	-
reviewed	BXGT013534	Cyclin-dependent kinase 5 activator 1	reviewed	Enzyme modulator	CDK5R1	-	9290	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	819	nM
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Ki	'='	10700	nM
P39748	BXGT010134	Flap endonuclease 1	reviewed	Enzyme	FEN1	Potency	-	63095	nM
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	79432	nM
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	reviewed	Enzyme modulator	CDK5R1	IC50	'='	9290	nM
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	reviewed	Kinase	CDK5	IC50	'='	9290	nM
P35821	BXGT009871	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	Ptpn1	Inhibition	-	-	-
Q9Y253	BXGT022216	DNA polymerase eta	reviewed	-	POLH	Potency	-	25118	nM
P32929	BXGT009682	Cystathionine gamma-lyase	reviewed	Enzyme	CTH	IC50	'>'	400000	nM
P56817	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	IC50	'>'	10000	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	79432	nM
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Inhibition	-	-	-
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	IC50	'='	9600	nM
P35520	BXGT009842	Cystathionine beta-synthase	reviewed	-	CBS	Inhibition	-	-	-
P35520	BXGT009842	Cystathionine beta-synthase	reviewed	-	CBS	IC50	'='	11500	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01780	Selaginella tamariscina	Selaginella tamariscina	Medicinal Plant
BXGF03423	Chimonanthus fragrans	Chimonanthus fragrans	Others
BXGF03714	Elsholtzia splendens	Elsholtzia splendens	Medicinal Plant
BXGF04602	Platycladus orientalis	Platycladus orientalis	Medicinal Plant
BXGF06095	Rheum undulatum	Rheum undulatum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}