Showing entry for Heat shock factor protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010049
Protein NameHeat shock factor protein 1
Uniport IdP38532
GeneHsf1
Gene Id15499
DomainHSF_DNA-bind; Vert_HS_TF
Pfam PF00447   PF06546  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034622 cellular protein-containing complex assembly
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:1904385 cellular response to angiotensin
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0072738 cellular response to diamide
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0071480 cellular response to gamma radiation
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:1904845 cellular response to L-glutamine
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:1904843 cellular response to nitroglycerin
Biological Process GO:0071407 cellular response to organic cyclic compound
Biological Process GO:0035865 cellular response to potassium ion
Biological Process GO:0071478 cellular response to radiation
Biological Process GO:1903936 cellular response to sodium arsenite
Biological Process GO:0034620 cellular response to unfolded protein
Biological Process GO:0006952 defense response
Biological Process GO:0006281 DNA repair
Biological Process GO:0001892 embryonic placenta development
Biological Process GO:0060136 embryonic process involved in female pregnancy
Biological Process GO:0007143 female meiotic nuclear division
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0006397 mRNA processing
Biological Process GO:0009299 mRNA transcription
Biological Process GO:0051028 mRNA transport
Biological Process GO:0010667 negative regulation of cardiac muscle cell apoptotic process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0090084 negative regulation of inclusion body assembly
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0031333 negative regulation of protein-containing complex assembly
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:1902512 positive regulation of apoptotic DNA fragmentation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0090261 positive regulation of inclusion body assembly
Biological Process GO:1904528 positive regulation of microtubule binding
Biological Process GO:0045931 positive regulation of mitotic cell cycle
Biological Process GO:1900365 positive regulation of mRNA polyadenylation
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:1900034 regulation of cellular response to heat
Biological Process GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress
Biological Process GO:0014823 response to activity
Biological Process GO:0032355 response to estradiol
Biological Process GO:0009408 response to heat
Biological Process GO:1990910 response to hypobaric hypoxia
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0007584 response to nutrient
Biological Process GO:1990911 response to psychosocial stress
Biological Process GO:0033574 response to testosterone
Biological Process GO:0007283 spermatogenesis
molecular function GO:0003682 chromatin binding
molecular function GO:0031490 chromatin DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0031072 heat shock protein binding
molecular function GO:0051879 Hsp90 protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:1990841 promoter-specific chromatin binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0043621 protein self-association
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0098847 sequence-specific single stranded DNA binding
molecular function GO:0097677 STAT family protein binding
molecular function GO:0061770 translation elongation factor binding
cellular component GO:0005813 centrosome
cellular component GO:0101031 chaperone complex
cellular component GO:0000777 condensed chromosome kinetochore
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0000791 euchromatin
cellular component GO:0000792 heterochromatin
cellular component GO:0042025 host cell nucleus
cellular component GO:0000776 kinetochore
cellular component GO:0097431 mitotic spindle pole
cellular component GO:0097165 nuclear stress granule
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0016605 PML body
cellular component GO:0045120 pronucleus
cellular component GO:0032991 protein-containing complex
cellular component GO:1990904 ribonucleoprotein complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001003 Coniferyl aldehyde 178.18
BXGC0003526 D-Xylopyranose 150.13
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
BXGC0015314 1-(2,6-Dihydroxyphenyl)Dodecan-1-One 292.2
BXGC0017790 coniferyl alcohol 180.08
BXGC0020737 Protoapigenone 286.05
BXGC0020995 6-[(3E,5E,7S)-5,7-Dimethyl-2-Oxonona-3,5-Dienyl]-2,4-Dihydroxy-3-Methylbenzaldehyde 316.17
BXGC0021676 Withaferin A 470.27
BXGC0022273 4-Methylabyssinone V 422.21
BXGC0024413 Emetine 480.3
BXGC0025200 2-Anilinonaphthalene-1,4-Dione 249.08
BXGC0035087 2,4-bis(4-hydroxybenzyl)phenol 306.13
BXGC0035776 BRUCEOLIDE 438.15
BXGC0038546 [(3Ar,4S,6Z,9E,11S,11Ar)-11-Hydroxy-6,10-Dimethyl-3-Methylidene-2,8-Dioxo-4,5,11,11A-Tetrahydro-3Ah-Cyclodeca[B]Furan-4-Yl] 2-Methylprop-2-Enoate 346.14
BXGC0044810 Lamivudine 229.05
BXGC0047086 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 281.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein