Showing entry for Heat shock 70 kDa protein 13


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010653
Protein NameHeat shock 70 kDa protein 13
Uniport IdP48723
GeneHSPA13
Gene Id6782
DomainHSP70
Pfam PF00012  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034620 cellular response to unfolded protein
Biological Process GO:0051085 chaperone cofactor-dependent protein refolding
Biological Process GO:0042026 protein refolding
Biological Process GO:0006986 response to unfolded protein
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0031072 heat shock protein binding
molecular function GO:0051787 misfolded protein binding
molecular function GO:0044183 protein folding chaperone
molecular function GO:0051082 unfolded protein binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0070062 extracellular exosome
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-2262752 Cellular responses to stress
R-HSA-3371453 Regulation of HSF1-mediated heat shock response
R-HSA-3371556 Cellular response to heat stress
R-HSA-8953897 Cellular responses to external stimuli
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0795875 BXGD010756 Chromosome 21 monosomy Pathological Conditions, Signs and Symptoms
C1297882 BXGD012244 Partial Trisomy Pathological Conditions, Signs and Symptoms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002616 Copper 63.55
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein