Showing entry for DNA primase small subunit



                       
General Target Information
BXGT IdBXGT010721
Protein NameDNA primase small subunit
Uniport IdP49642
GenePRIM1
Gene Id5557
DomainDNA_primase_S
Pfam PF01896  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.4 Replication and repair hsa03030 DNA replication
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006269 DNA replication, synthesis of RNA primer
Biological Process GO:0006270 DNA replication initiation
Biological Process GO:0000082 G1/S transition of mitotic cell cycle
Biological Process GO:0032201 telomere maintenance via semi-conservative replication
molecular function GO:0003896 DNA primase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0003697 single-stranded DNA binding
cellular component GO:0005658 alpha DNA polymerase:primase complex
cellular component GO:0016020 membrane
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1
R-HSA-113510 E2F mediated regulation of DNA replication
R-HSA-157579 Telomere Maintenance
R-HSA-1640170 Cell Cycle
R-HSA-174411 Polymerase switching on the C-strand of the telomere
R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis
R-HSA-174430 Telomere C-strand synthesis initiation
R-HSA-180786 Extension of Telomeres
R-HSA-453279 Mitotic G1 phase and G1/S transition
R-HSA-68952 DNA replication initiation
R-HSA-68962 Activation of the pre-replicative complex
R-HSA-69002 DNA Replication Pre-Initiation
R-HSA-69091 Polymerase switching
R-HSA-69109 Leading Strand Synthesis
R-HSA-69166 Removal of the Flap Intermediate
R-HSA-69183 Processive synthesis on the lagging strand
R-HSA-69186 Lagging Strand Synthesis
R-HSA-69190 DNA strand elongation
R-HSA-69206 G1/S Transition
R-HSA-69239 Synthesis of DNA
R-HSA-69242 S Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69306 DNA Replication
R-HSA-73886 Chromosome Maintenance
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014772 BXGD000948 Red Blood Cell Count measurement
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0027651 BXGD002009 Neoplasms Neoplasms
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0424678 BXGD008537 Lean body mass
C0427460 BXGD008616 Red cell distribution width determination
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1629609 BXGD013479 Age at menopause
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein