adisease

Showing entry for Age at menarche

General Disease Information
BXGD Id	BXGD012388
Disease Name	Age at menarche
Disease CUI Id	C1314691
MeSH Codes	F01
Disease Class Name	Behavior and Behavior Mechanisms
Semantic Type	Finding
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A1Z1Q3	BXGT001069	ADP-ribose glycohydrolase MACROD2	140733	reviewed
O00189	BXGT003891	AP-4 complex subunit mu-1	9179	reviewed	Extracellular structure
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O60307	BXGT004870	Microtubule-associated serine/threonine-protein kinase 3	23031	reviewed	Kinase
O75164	BXGT005104	Lysine-specific demethylase 4A	9682	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P10828	BXGT007624	Thyroid hormone receptor beta	7068	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P23468	BXGT008870	Receptor-type tyrosine-protein phosphatase delta	5789	reviewed	Enzyme
P23528	BXGT008879	Cofilin-1	1072	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P31946	BXGT009588	14-3-3 protein beta/alpha	7529	reviewed	Chaperone
P32297	BXGT009616	Neuronal acetylcholine receptor subunit alpha-3	1136	reviewed	Ion channel
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P41968	BXGT010275	Melanocortin receptor 3	4159	reviewed	G-protein coupled receptor
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48443	BXGT010631	Retinoic acid receptor RXR-gamma	6258	reviewed	Nuclear receptor
P49642	BXGT010721	DNA primase small subunit	5557	reviewed	Enzyme
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P54756	BXGT011074	Ephrin type-A receptor 5	2044	reviewed	Kinase
P56545	BXGT011178	C-terminal-binding protein 2	1488	reviewed	Transcription factor
P57772	BXGT011220	Selenocysteine-specific elongation factor	60678	reviewed	Enzyme
Q04637	BXGT012771	Eukaryotic translation initiation factor 4 gamma 1	1981	reviewed	Nucleic acid binding
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13163	BXGT013321	Dual specificity mitogen-activated protein kinase kinase 5	5607	reviewed	Kinase
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13639	BXGT013389	5-hydroxytryptamine receptor 4	3360	reviewed	G-protein coupled receptor
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14914	BXGT013513	Prostaglandin reductase 1	22949	reviewed	Enzyme
Q15139	BXGT013546	Serine/threonine-protein kinase D1	5587	reviewed	Kinase
Q15262	BXGT013555	Receptor-type tyrosine-protein phosphatase kappa	5796	reviewed	Enzyme
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q16566	BXGT013639	Calcium/calmodulin-dependent protein kinase type IV	814	reviewed	Kinase
Q2M2I8	BXGT014130	AP2-associated protein kinase 1	22848	reviewed	Kinase
Q59H18	BXGT015278	Serine/threonine-protein kinase TNNI3K	51086	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6ZN17	BXGT016631	Protein lin-28 homolog B	389421	reviewed
Q7LBC6	BXGT016998	Lysine-specific demethylase 3B	51780	reviewed	Epigenetic regulator
Q8N807	BXGT018527	Protein disulfide-isomerase-like protein of the testis	204474	reviewed
Q8WZ19	BXGT019022	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1	253980	reviewed
Q92932	BXGT019395	Receptor-type tyrosine-protein phosphatase N2	5799	reviewed
Q92953	BXGT019398	Potassium voltage-gated channel subfamily B member 2	9312	reviewed	Ion channel
Q969R2	BXGT019611	Oxysterol-binding protein 2	23762	reviewed
Q96GD3	BXGT019666	Polycomb protein SCMH1	22955	reviewed	Nucleic acid binding
Q96QU1	BXGT019721	Protocadherin-15	65217	reviewed
Q96RL1	BXGT019730	BRCA1-A complex subunit RAP80	51720	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9H3R0	BXGT020465	Lysine-specific demethylase 4C	23081	reviewed
Q9HD67	BXGT020544	Unconventional myosin-X	4651	reviewed
Q9NP56	BXGT021142	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	27115	reviewed
Q9NPC2	BXGT021150	Potassium channel subfamily K member 9	51305	reviewed	Ion channel
Q9NSI6	BXGT021208	Bromodomain and WD repeat-containing protein 1	54014	reviewed
Q9NT68	BXGT021210	Teneurin-2	57451	reviewed
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9UH77	BXGT021692	Kelch-like protein 3	26249	reviewed
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q13029	BXGT022688	PR domain zinc finger protein 2	7799	reviewed
O00308	BXGT023349	NEDD4-like E3 ubiquitin-protein ligase WWP2	11060	reviewed	Enzyme
O14490	BXGT023570	Disks large-associated protein 1	9229	reviewed	Receptor
O15016	BXGT024295	Tripartite motif-containing protein 66	9866	reviewed
P29590	BXGT024350	Protein PML	5371	reviewed
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	2530	reviewed
Q8N122	BXGT026091	Regulatory-associated protein of mTOR	57521	reviewed
Q58A45	BXGT026131	PAN2-PAN3 deadenylation complex subunit PAN3	255967	reviewed	Kinase

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}