Showing entry for Ras-related protein Rab-5C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010834
Protein NameRas-related protein Rab-5C
Uniport IdP51148
GeneRAB5C
Gene Id5878
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
5. Organismal Systems 5.5 Excretory system hsa04962 Vasopressin-regulated water reabsorption
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006897 endocytosis
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0048227 plasma membrane to endosome transport
Biological Process GO:0030100 regulation of endocytosis
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
cellular component GO:0035577 azurophil granule membrane
cellular component GO:0005769 early endosome
cellular component GO:0031901 early endosome membrane
cellular component GO:0030139 endocytic vesicle
cellular component GO:0012505 endomembrane system
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0005811 lipid droplet
cellular component GO:0005765 lysosomal membrane
cellular component GO:0042470 melanosome
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-199991 Membrane Trafficking
R-HSA-199992 trans-Golgi Network Vesicle Budding
R-HSA-392499 Metabolism of proteins
R-HSA-432722 Golgi Associated Vesicle Biogenesis
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6798695 Neutrophil degranulation
R-HSA-8854214 TBC/RABGAPs
R-HSA-8856828 Clathrin-mediated endocytosis
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0024266 BXGD001754 Lymphocytic Choriomeningitis Infections; Nervous System Diseases
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0149978 BXGD003397 Adenocarcinoma of rectum Digestive System Diseases; Neoplasms
C0153014 BXGD003612 Non-arthropod borne lymphocytic choriomeningitis Infections; Nervous System Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0279584 BXGD006641 Childhood B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279593 BXGD006644 Adult B Acute Lymphoblastic Leukemia
C0337428 BXGD007155 Fibrinogen assay
C0349636 BXGD007941 Pre B-cell acute lymphoblastic leukemia
C0523465 BXGD009209 Serum albumin measurement
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239219 BXGD016966 von Willebrand's factor (lab test)
C2825857 BXGD017777 Factor VIII measurement
C3150797 BXGD018337 AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
C4014795 BXGD020166 AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
C4310768 BXGD022658 AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein