Showing entry for Adenocarcinoma of rectum


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003397
Disease NameAdenocarcinoma of rectum
Disease CUI IdC0149978
MeSH Codes C06   C04  
Disease Class NameDigestive System Diseases; Neoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00194 BXGT003892 Ras-related protein Rab-27B 5874 reviewed
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 9133 reviewed Enzyme modulator
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 10411 reviewed Enzyme modulator
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51148 BXGT010834 Ras-related protein Rab-5C 5878 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q08828 BXGT013008 Adenylate cyclase type 1 107 reviewed
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q14002 BXGT013433 Carcinoembryonic antigen-related cell adhesion molecule 7 1087 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q6P589 BXGT016452 Tumor necrosis factor alpha-induced protein 8-like protein 2 79626 reviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P40198 BXGT023750 Carcinoembryonic antigen-related cell adhesion molecule 3 1084 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q96MU7 BXGT025897 YTH domain-containing protein 1 91746 reviewed
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease