Showing entry for Regulator of G-protein signaling 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011219
Protein NameRegulator of G-protein signaling 8
Uniport IdP57771
GeneRGS8
Gene Id85397
DomainRGS
Pfam PF00615  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0009968 negative regulation of signal transduction
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0060159 regulation of dopamine receptor signaling pathway
molecular function GO:0005096 GTPase activator activity
molecular function GO:0003924 GTPase activity
cellular component GO:0030425 dendrite
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-418594 G alpha (i) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0752121 BXGD010669 Spinocerebellar Ataxia Type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2931456 BXGD018024 Prostate cancer, familial Neoplasms; Male Urogenital Diseases
C4722327 BXGD023799 PROSTATE CANCER, HEREDITARY, 1 Neoplasms; Male Urogenital Diseases
C4722328 BXGD023800 Hereditary Prostate Carcinoma Neoplasms; Male Urogenital Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0016421 punicalin 782.06
BXGC0050823 Chebulinic acid 956.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein