Showing entry for Spinocerebellar Ataxia Type 2


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010669
Disease NameSpinocerebellar Ataxia Type 2
Disease CUI IdC0752121
MeSH Codes C16   C10  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14578 BXGT004072 Citron Rho-interacting kinase 11113 reviewed Kinase
O43424 BXGT004592 Glutamate receptor ionotropic, delta-2 2895 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O95405 BXGT005379 Zinc finger FYVE domain-containing protein 9 9372 reviewed
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
O95793 BXGT005397 Double-stranded RNA-binding protein Staufen homolog 1 6780 reviewed
P00439 BXGT005539 Phenylalanine-4-hydroxylase 5053 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05129 BXGT006322 Protein kinase C gamma type 5582 reviewed Kinase
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P57771 BXGT011219 Regulator of G-protein signaling 8 85397 reviewed Enzyme modulator
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q14643 BXGT013493 Inositol 1,4,5-trisphosphate receptor type 1 3708 reviewed Ion channel
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9GZZ9 BXGT020430 Ubiquitin-like modifier-activating enzyme 5 79876 reviewed Enzyme
Q9H4Y5 BXGT020479 Glutathione S-transferase omega-2 119391 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9UH03 BXGT021690 Neuronal-specific septin-3 55964 reviewed Enzyme modulator
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9NYP7 BXGT022661 Elongation of very long chain fatty acids protein 5 60481 reviewed Enzyme
Q9Y5W7 BXGT022783 Sorting nexin-14 57231 reviewed Enzyme modulator
Q96I25 BXGT024184 Splicing factor 45 84991 reviewed Nucleic acid binding
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
Q6IQ55 BXGT025689 Tau-tubulin kinase 2 146057 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease