Showing entry for Purine nucleoside phosphorylase



                       
General Target Information
BXGT IdBXGT012080
Protein NamePurine nucleoside phosphorylase
Uniport IdP85973
GenePnp
Gene Id290029
DomainPNP_UDP_1
Pfam PF01048  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006955 immune response
Biological Process GO:0006148 inosine catabolic process
Biological Process GO:0032623 interleukin-2 production
Biological Process GO:0006738 nicotinamide riboside catabolic process
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0009165 nucleotide biosynthetic process
Biological Process GO:0046638 positive regulation of alpha-beta T cell differentiation
Biological Process GO:0042102 positive regulation of T cell proliferation
Biological Process GO:0043101 purine-containing compound salvage
Biological Process GO:0042278 purine nucleoside metabolic process
Biological Process GO:0042493 response to drug
Biological Process GO:0034418 urate biosynthetic process
molecular function GO:0008144 drug binding
molecular function GO:0042802 identical protein binding
molecular function GO:0001882 nucleoside binding
molecular function GO:0042301 phosphate ion binding
molecular function GO:0002060 purine nucleobase binding
molecular function GO:0004731 purine-nucleoside phosphorylase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002786 Hypoxanthine 136.11
BXGC0002912 Guanine 151.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein