Showing entry for Alpha-2C adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012583
Protein NameAlpha-2C adrenergic receptor
Uniport IdQ01337
GeneAdra2c
Gene Id11553
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032148 activation of protein kinase B activity
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0071875 adrenergic receptor signaling pathway
Biological Process GO:0007565 female pregnancy
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0070473 negative regulation of uterine smooth muscle contraction
Biological Process GO:0030168 platelet activation
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0035624 receptor transactivation
Biological Process GO:0051930 regulation of sensory perception of pain
molecular function GO:0031694 alpha-2A adrenergic receptor binding
molecular function GO:0004938 alpha2-adrenergic receptor activity
molecular function GO:0051379 epinephrine binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0030424 axon
cellular component GO:0043679 axon terminus
cellular component GO:0005737 cytoplasm
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0043025 neuronal cell body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0017443 Phenylephrine 167.09
BXGC0021893 Norepinephrine 169.07
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein