Showing entry for 5-hydroxytryptamine receptor 2B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012637
Protein Name5-hydroxytryptamine receptor 2B
Uniport IdQ02152
GeneHtr2b
Gene Id15559
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0007610 behavior
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0003300 cardiac muscle hypertrophy
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0071418 cellular response to amine stimulus
Biological Process GO:1904015 cellular response to serotonin
Biological Process GO:0071502 cellular response to temperature stimulus
Biological Process GO:0019934 cGMP-mediated signaling
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0048598 embryonic morphogenesis
Biological Process GO:0070371 ERK1 and ERK2 cascade
Biological Process GO:0002031 G protein-coupled receptor internalization
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0007507 heart development
Biological Process GO:0003007 heart morphogenesis
Biological Process GO:0014827 intestine smooth muscle contraction
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0010507 negative regulation of autophagy
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0014033 neural crest cell differentiation
Biological Process GO:0001755 neural crest cell migration
Biological Process GO:0014065 phosphatidylinositol 3-kinase signaling
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
Biological Process GO:0016310 phosphorylation
Biological Process GO:0051781 positive regulation of cell division
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0001819 positive regulation of cytokine production
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0043406 positive regulation of MAP kinase activity
Biological Process GO:0051000 positive regulation of nitric-oxide synthase activity
Biological Process GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0070528 protein kinase C signaling
Biological Process GO:0050795 regulation of behavior
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0042493 response to drug
Biological Process GO:0007210 serotonin receptor signaling pathway
Biological Process GO:0042310 vasoconstriction
molecular function GO:0008144 drug binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0005096 GTPase activator activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000548 Tryptamine 160.22
BXGC0005867 Serotonin 176.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein