Showing entry for Uridine phosphorylase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013677
Protein NameUridine phosphorylase 1
Uniport IdQ16831
GeneUPP1
Gene Id7378
DomainPNP_UDP_1
Pfam PF01048  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0009166 nucleotide catabolic process
Biological Process GO:0046135 pyrimidine nucleoside catabolic process
Biological Process GO:0043097 pyrimidine nucleoside salvage
Biological Process GO:0044206 UMP salvage
Biological Process GO:0006218 uridine catabolic process
molecular function GO:0042802 identical protein binding
molecular function GO:0004850 uridine phosphorylase activity
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-73614 Pyrimidine salvage
R-HSA-73621 Pyrimidine catabolism
R-HSA-8956319 Nucleobase catabolism
R-HSA-8956321 Nucleotide salvage
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0014518 BXGD000921 Toxic Epidermal Necrolysis Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017536 BXGD001114 Giardiasis Digestive System Diseases; Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026640 BXGD001912 Mouth Neoplasms Neoplasms; Stomatognathic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0035228 BXGD002515 Respiratory Hypersensitivity Respiratory Tract Diseases; Immune System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0162820 BXGD003985 Dermatitis, Allergic Contact Skin and Connective Tissue Diseases; Immune System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0339543 BXGD007267 Epiretinal Membrane Eye Diseases
C0345964 BXGD007755 Adenoma of lung Neoplasms
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C4523900 BXGD023082 Axonal edema
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0050471 Fluorouracil 130.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein