Showing entry for Malignant neoplasm of thyroid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000432
Disease NameMalignant neoplasm of thyroid
Disease CUI IdC0007115
MeSH Codes C04   C19  
Disease Class NameNeoplasms; Endocrine System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15374 BXGT004157 Monocarboxylate transporter 5 9122 reviewed Transporter
O15382 BXGT004160 Branched-chain-amino-acid aminotransferase, mitochondrial 587 reviewed Enzyme
O15427 BXGT004167 Monocarboxylate transporter 4 9123 reviewed Transporter
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43597 BXGT004602 Protein sprouty homolog 2 10253 reviewed Signaling
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 699 reviewed Kinase
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60271 BXGT004866 C-Jun-amino-terminal kinase-interacting protein 4 9043 reviewed Enzyme modulator
O60566 BXGT004884 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 701 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O60882 BXGT004905 Matrix metalloproteinase-20 9313 reviewed Enzyme
O75223 BXGT005106 Gamma-glutamylcyclotransferase 79017 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O76094 BXGT005177 Signal recognition particle subunit SRP72 6731 reviewed
O94813 BXGT005337 Slit homolog 2 protein 9353 reviewed
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 11309 reviewed Transporter
O95257 BXGT005365 Growth arrest and DNA damage-inducible protein GADD45 gamma 10912 reviewed
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 9448 reviewed Kinase
O95931 BXGT005407 Chromobox protein homolog 7 23492 reviewed Epigenetic regulator
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
O96020 BXGT005416 G1/S-specific cyclin-E2 9134 reviewed Enzyme modulator
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00387 BXGT005525 NADH-cytochrome b5 reductase 3 1727 reviewed
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02724 BXGT005934 Glycophorin-A 2993 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02760 BXGT005948 Protein AMBP 259 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04066 BXGT006142 Tissue alpha-L-fucosidase 2517 reviewed
P04083 BXGT006147 Annexin A1 301 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06454 BXGT006441 Prothymosin alpha 5757 reviewed
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07947 BXGT006701 Tyrosine-protein kinase Yes 7525 reviewed Kinase
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P07998 BXGT006711 Ribonuclease pancreatic 6035 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08133 BXGT006727 Annexin A6 309 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08758 BXGT006821 Annexin A5 308 reviewed
P08833 BXGT006827 Insulin-like growth factor-binding protein 1 3484 reviewed Enzyme modulator
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10398 BXGT007564 Serine/threonine-protein kinase A-Raf 369 reviewed Kinase
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10586 BXGT007581 Receptor-type tyrosine-protein phosphatase F 5792 reviewed Enzyme
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P10827 BXGT007623 Thyroid hormone receptor alpha 7067 reviewed Nuclear receptor
P10828 BXGT007624 Thyroid hormone receptor beta 7068 reviewed Nuclear receptor
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13489 BXGT007913 Ribonuclease inhibitor 6050 reviewed Transcription factor
P13497 BXGT007915 Bone morphogenetic protein 1 649 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13640 BXGT007935 Metallothionein-1G 4495 reviewed
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type 239 reviewed Enzyme
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18754 BXGT008423 Regulator of chromosome condensation 1104 reviewed
P18846 BXGT008430 Cyclic AMP-dependent transcription factor ATF-1 466 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20132 BXGT008546 L-serine dehydratase/L-threonine deaminase 10993 reviewed Enzyme
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21583 BXGT008667 Kit ligand 4254 reviewed
P21675 BXGT008678 Transcription initiation factor TFIID subunit 1 6872 reviewed Kinase
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30044 BXGT009395 Peroxiredoxin-5, mitochondrial 25824 reviewed
P30046 BXGT009396 D-dopachrome decarboxylase 1652 reviewed Enzyme
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30536 BXGT009435 Translocator protein 706 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30825 BXGT009469 High affinity cationic amino acid transporter 1 6541 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31939 BXGT009584 Bifunctional purine biosynthesis protein PURH 471 reviewed Enzyme
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P32745 BXGT009663 Somatostatin receptor type 3 6753 reviewed G-protein coupled receptor
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35579 BXGT009852 Myosin-9 4627 reviewed
P35613 BXGT009856 Basigin 682 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P36896 BXGT009940 Activin receptor type-1B 91 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38919 BXGT010072 Eukaryotic initiation factor 4A-III 9775 reviewed
P40261 BXGT010170 Nicotinamide N-methyltransferase 4837 reviewed Enzyme
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43003 BXGT010347 Excitatory amino acid transporter 1 6507 reviewed Transporter
P43351 BXGT010380 DNA repair protein RAD52 homolog 5893 reviewed Nucleic acid binding
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46940 BXGT010556 Ras GTPase-activating-like protein IQGAP1 8826 reviewed Enzyme modulator
P47736 BXGT010579 Rap1 GTPase-activating protein 1 5909 reviewed Enzyme modulator
P48067 BXGT010619 Sodium- and chloride-dependent glycine transporter 1 6536 reviewed Transporter
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49798 BXGT010745 Regulator of G-protein signaling 4 5999 reviewed Enzyme modulator
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P52597 BXGT010937 Heterogeneous nuclear ribonucleoprotein F 3185 reviewed Nucleic acid binding
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P52895 BXGT010961 Aldo-keto reductase family 1 member C2 1646 reviewed Enzyme
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61088 BXGT011358 Ubiquitin-conjugating enzyme E2 N 7334 reviewed
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P62491 BXGT011430 Ras-related protein Rab-11A 8766 reviewed
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 1020 reviewed Kinase
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q01726 BXGT012610 Melanocyte-stimulating hormone receptor 4157 reviewed G-protein coupled receptor
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04759 BXGT012781 Protein kinase C theta type 5588 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06710 BXGT012887 Paired box protein Pax-8 7849 reviewed
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q09028 BXGT013025 Histone-binding protein RBBP4 5928 reviewed
Q12913 BXGT013279 Receptor-type tyrosine-protein phosphatase eta 5795 reviewed Enzyme
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13043 BXGT013307 Serine/threonine-protein kinase 4 6789 reviewed Kinase
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13188 BXGT013324 Serine/threonine-protein kinase 3 6788 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q13426 BXGT013353 DNA repair protein XRCC4 7518 reviewed
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q14032 BXGT013438 Bile acid-CoA:amino acid N-acyltransferase 570 reviewed
Q14103 BXGT013439 Heterogeneous nuclear ribonucleoprotein D0 3184 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14449 BXGT013470 Growth factor receptor-bound protein 14 2888 reviewed Receptor
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14527 BXGT013479 Helicase-like transcription factor 6596 reviewed
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15717 BXGT013589 ELAV-like protein 1 1994 reviewed
Q15788 BXGT013598 Nuclear receptor coactivator 1 8648 reviewed Kinase
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q16831 BXGT013677 Uridine phosphorylase 1 7378 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q7Z7D3 BXGT017262 V-set domain-containing T-cell activation inhibitor 1 79679 reviewed Enzyme modulator
Q86Z14 BXGT017639 Beta-klotho 152831 reviewed Enzyme
Q8N339 BXGT018503 Metallothionein-1M 4499 reviewed
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q8WWV3 BXGT019005 Reticulon-4-interacting protein 1, mitochondrial 84816 reviewed
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q8WYH8 BXGT019019 Inhibitor of growth protein 5 84289 reviewed Nucleic acid binding
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q95460 BXGT019580 Major histocompatibility complex class I-related gene protein 3140 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96GX5 BXGT019668 Serine/threonine-protein kinase greatwall 84930 reviewed Kinase
Q96JA1 BXGT019681 Leucine-rich repeats and immunoglobulin-like domains protein 1 26018 reviewed Receptor
Q99523 BXGT019929 Sortilin 6272 reviewed Transporter
Q99527 BXGT019930 G-protein coupled estrogen receptor 1 2852 reviewed G-protein coupled receptor
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 28996 reviewed Kinase
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HCE7 BXGT020532 E3 ubiquitin-protein ligase SMURF1 57154 reviewed Enzyme
Q9HD26 BXGT020540 Golgi-associated PDZ and coiled-coil motif-containing protein 57120 reviewed
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NUX5 BXGT021220 Protection of telomeres protein 1 25913 reviewed Nucleic acid binding
Q9NWT6 BXGT021234 Hypoxia-inducible factor 1-alpha inhibitor 55662 reviewed
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P0J0 BXGT021287 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 51079 reviewed Enzyme
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UBZ9 BXGT021666 DNA repair protein REV1 51455 reviewed
Q9UHX3 BXGT021708 Adhesion G protein-coupled receptor E2 30817 reviewed G-protein coupled receptor
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UN36 BXGT021780 Protein NDRG2 57447 reviewed Enzyme
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9UQ80 BXGT021806 Proliferation-associated protein 2G4 5036 reviewed
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
Q9NQG6 BXGT022733 Mitochondrial dynamics protein MID51 54471 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q5U651 BXGT023159 Ras-interacting protein 1 54922 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q9H461 BXGT024943 Frizzled-8 8325 reviewed G-protein coupled receptor
P38646 BXGT024954 Stress-70 protein, mitochondrial 3313 reviewed
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
P28715 BXGT025675 DNA repair protein complementing XP-G cells 2073 reviewed
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
Q8IVT5 BXGT026146 Kinase suppressor of Ras 1 8844 reviewed Kinase
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease