Showing entry for Beta-1 adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013958
Protein NameBeta-1 adrenergic receptor
Uniport IdQ28998
GeneADRB1
Gene Id397355
Domain7tm_1
Pfam PF00001  
OrganismSus scrofa (Pig)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
Biological Process GO:0045187 regulation of circadian sleep/wake cycle, sleep
molecular function GO:0004940 beta1-adrenergic receptor activity
molecular function GO:0051379 epinephrine binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0051380 norepinephrine binding
molecular function GO:0005088 Ras guanyl-nucleotide exchange factor activity
cellular component GO:0005769 early endosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042222 Propranolol 259.16
BXGC0044017 Verapamil 454.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein