acompound

Showing entry for Propranolol

General Compound Information
BXGC Id	BXGC0042222
Compound Name	Propranolol
Structure
Formula	C16H21NO2
InchiKey	AQHHHDLHHXJYJD-UHFFFAOYSA-N
SMILES	OC(COc1cccc2c1cccc2)CNC(C)C
Inchi	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
IUPAC	1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
Molecular Weight	259.16
Pubchem Id	4946
Chembl Id	CHEMBL27

Targets of Information Source

DrugBank

DB00571

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	approved; investigational	antagonist
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	approved; investigational	antagonist
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	approved; investigational	antagonist
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	approved; investigational	other/unknown
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	approved; investigational	other/unknown

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

25761

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	-	6.9	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	-	-	0.83	-
reviewed	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	-	-	117	-
reviewed	BXGT009621	5-hydroxytryptamine receptor 7	reviewed		Htr7	5000	-	-	-
reviewed	BXGT009621	5-hydroxytryptamine receptor 7	reviewed		Htr7	7000	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	400	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	2.1	-	-	-
reviewed	BXGT010360	Alpha-1A adrenergic receptor	reviewed		Adra1a	5900	-	-	-
reviewed	BXGT010360	Alpha-1A adrenergic receptor	reviewed		Adra1a	6900	-	-	-
reviewed	BXGT019575	D(1A) dopamine receptor	reviewed		DRD1	>10000	-	-	-
reviewed	BXGT008560	D(2) dopamine receptor	reviewed		DRD2	2800	-	-	-
reviewed	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	640	-	-	-
reviewed	BXGT009486	5-hydroxytryptamine receptor 5A	reviewed		Htr5a	>10000	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	39	-	-	-
reviewed	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	31	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	7079.46	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	77.62	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	81.28	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	0.69	-	-	-
reviewed	BXGT007586	Beta-2 adrenergic receptor	reviewed		Adrb2	43.65	-	-	-
reviewed	BXGT007586	Beta-2 adrenergic receptor	reviewed		Adrb2	0.46	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	2000	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	>10000	-	-	-
reviewed	BXGT008728	Alpha-2C adrenergic receptor	reviewed		Adra2c	1297	-	-	-
reviewed	BXGT008728	Alpha-2C adrenergic receptor	reviewed		Adra2c	2789	-	-	-
reviewed	BXGT009565	Sodium-dependent serotonin transporter	reviewed		Slc6a4	3700	-	-	-
reviewed	BXGT006838	5-hydroxytryptamine receptor 2C	reviewed		Htr2c	1200	-	-	-
reviewed	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	>10000	-	-	-
reviewed	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	55	-	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	2.69	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	0.38	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	0.61	-	-	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	0.79	-	-	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	0.83	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	57.54	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	5.01	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	30.9	-	-	-
reviewed	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	2691.53	-	-	-
reviewed	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	>10000	-	-	-
reviewed	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	630.95	-	-	-
reviewed	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	56.23	-	-	-
reviewed	BXGT007586	Beta-2 adrenergic receptor	reviewed		Adrb2	>10000	-	-	-
reviewed	BXGT021415	5-hydroxytryptamine receptor 6	reviewed		Htr6	>10000	-	-	-
reviewed	BXGT009531	5-hydroxytryptamine receptor 5B	reviewed		Htr5b	6309.57	-	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	0.02	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	0.01	-	-	-
reviewed	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	272	-	-	-
reviewed	BXGT008059	5-hydroxytryptamine receptor 2A	reviewed		Htr2a	1047	-	-	-
reviewed	BXGT006838	5-hydroxytryptamine receptor 2C	reviewed		Htr2c	2457	-	-	-
reviewed	BXGT008938	5-hydroxytryptamine receptor 3A	reviewed		Htr3a	>10000	-	-	-
reviewed	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	>10000	-	-	-
reviewed	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	>10000	-	-	-
reviewed	BXGT011367	D(2) dopamine receptor	reviewed		Drd2	>10000	-	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	1.8	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	0.8	-	-	-
reviewed	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	186	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	3	-	-	-
reviewed	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	-	-	>100000	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	-	-	4.4	-
reviewed	BXGT011086	Beta-2 adrenergic receptor	reviewed		ADRB2	-	17	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	-	-	2630	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	-	-	2.4	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	2.3	-	-	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	-	-	7.9	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	-	-	0.239883	-
reviewed	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	-	-	0.60256	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	-	1.8	-
reviewed	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	-	-	214	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	-	6	-
reviewed	BXGT007595	Cytochrome P450 2D6	reviewed		CYP2D6	-	1900	-	-
reviewed	BXGT013478	Sodium channel protein type 5 subunit alpha	reviewed	Ion channel	SCN5A	-	2100	-	-
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	18000	-	-
reviewed	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	-	2828	-	-
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	21000	-	-
reviewed	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	-	>1000000	-	-
reviewed	BXGT005057	Bile salt export pump	reviewed		Abcb11	-	>1000000	-	-
reviewed	BXGT010867	Cytochrome P450 2J2	reviewed		CYP2J2	-	>50000	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	9700	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	7	-	-	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	-	10229
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	-	30	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	4	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	6.5	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	1600	-	-	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	2.4	-	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	12	-	-
reviewed	BXGT011367	D(2) dopamine receptor	reviewed		Drd2	12902	-	-	-
reviewed	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed		Htr1a	90	-	-	-
reviewed	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed		Htr1b	50	-	-	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	18	-	-
reviewed	BXGT008448	D(3) dopamine receptor	reviewed		Drd3	>5000	-	-	-
reviewed	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed		Htr1a	113	-	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	573000	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	48000	-	-	-
reviewed	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	-	63200	-	-
reviewed	BXGT013515	Sodium/bile acid cotransporter	reviewed	Transporter	SLC10A1	-	5500	-	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	3.39	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	43.65	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	1.26	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	3.02	-
reviewed	BXGT011086	Beta-2 adrenergic receptor	reviewed		ADRB2	-	-	1.78	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	-	0.977	-
reviewed	BXGT008380	Beta-1 adrenergic receptor	reviewed		Adrb1	-	-	4.37	-
reviewed	BXGT018404	Beta-2 adrenergic receptor	reviewed		Adrb2	-	29	-	-
reviewed	BXGT005955	Serum albumin	reviewed	Transporter	ALB	-	-	436516	-
reviewed	BXGT005955	Serum albumin	reviewed	Transporter	ALB	-	-	354813	-
reviewed	BXGT005955	Serum albumin	reviewed	Transporter	ALB	-	-	660693	-
reviewed	BXGT005955	Serum albumin	reviewed	Transporter	ALB	-	-	602560	-
reviewed	BXGT005955	Serum albumin	reviewed	Transporter	ALB	-	-	630957	-
reviewed	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	-	-	162	-
reviewed	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	-	-	200	-

CHEMBL

CHEMBL27

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ratio	'='	2	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ratio	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	IC50	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	Ki	-	-	-
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	IC50	-	-	-
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	IC50	-	-	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	IC50	-	-	-
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	IC50	-	-	-
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	Ki	-	-	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	Ki	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	ED50	'='	62	mg.kg-1
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	ED50	'='	62	mg.kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ED50	'='	62	mg.kg-1
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	Vasodilation	'='	7	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'>'	10000	nM
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	Ki	-	-	-
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	Ki	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	IC50	-	-	-
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Inhibition	'='	56	%
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Inhibition	'='	56	%
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	56	%
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	1	nM
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	'='	113	nM
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	FC	'='	1	-
P19020	BXGT008448	D(3) dopamine receptor	reviewed	-	Drd3	Ki	'>'	5000	nM
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	21000	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Intrinsic activity	'='	0	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Intrinsic activity	'='	0	-
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Specificity	'>'	100000	-
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Specificity	'>'	100000	-
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Specificity	'>'	100000	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	EC50	'='	10229	ug
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	3	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	'='	0	nM
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	IC50	-	-	-
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	9700	nM
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	Ki	-	-	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Ki	-	-	-
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	IC50	-	-	-
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	IC50	-	-	-
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	IC50	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	Ki	'='	218	nM
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	Ki	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	Ki	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	Ki	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Ki	-	-	-
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	Ki	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	IC50	'='	2294	nM
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	Ki	-	-	-
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	EC50	'>'	5011	nM
O15244	BXGT004140	Solute carrier family 22 member 2	reviewed	Transporter	SLC22A2	Activity	-	-	-
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	IC50	-	-	-
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	Ki	-	-	-
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	IC50	-	-	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	-	-	-
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	Ki	-	-	-
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	IC50	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	IC50	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	IC50	-	-	-
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	IC50	-	-	-
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	IC50	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	Ki	-	-	-
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	Ki	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	Ki	'='	419	nM
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	Ki	-	-	-
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	Ki	'='	1206	nM
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	IC50	'='	12	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	'='	12	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	'='	12	nM
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	Activity	'='	69	%
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	EC50	'>'	5011	nM
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	EC50	'>'	5011	nM
P30556	BXGT009441	Type-1 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR1	EC50	'>'	5011	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	Ki	-	-	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	IC50	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	Ki	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	IC50	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Ki	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	IC50	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	IC50	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	IC50	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	IC50	-	-	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	240	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	3	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	3	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	3	nM
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Potency	-	14125	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	DR10	'='	0	mg kg-1
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	ED50	'='	0	mg.kg-1
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	ED50	'='	0	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	ED50	'='	0	mg.kg-1
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	12	%
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	DR10	'='	0	mg kg-1
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	514	nm/s
Q06278	BXGT012869	Aldehyde oxidase	reviewed	Enzyme	AOX1	Fm	'='	0	-
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	IC50	'>'	5011	nM
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	IC50	'>'	5011	nM
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	IC50	'>'	5011	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	504	nm/s
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Ki	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	ED50	'='	0	mg.kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ED50	'='	0	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Kd	'='	2	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Binding site fraction	'='	0	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	3	nM
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Ki	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	Ki	'='	1202	nM
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	Ki	-	-	-
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	IC50	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	IC50	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	'='	139	nM
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	IC50	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	IC50	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'='	4000	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	'='	2000	nM
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	Ki	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Contractile force	'='	7	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	ISA	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	ISA	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ISA	-	-	-
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Kd	'='	4	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kb	'='	0	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kb	'='	0	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kb	'='	0	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	1	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	1	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	1	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	199	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	EC50	'='	1911	ug
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	IC50	'='	243	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	-	-	-
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	Ki	-	-	-
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Ki	'='	1600	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Ki	'='	1600	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	1600	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	48000	nM
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	IC50	'='	17	nM
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	Inhibition	'<'	10	%
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	43	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	IC50	'='	3	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	IC50	'='	3	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	IC50	'='	3	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	73	%
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	49	%
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	10	nM
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	IC50	-	-	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Affinity constant	'='	0	uM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Ki	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ratio	'='	0	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ratio	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	% maximum response	'='	-6	%
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	DOSE	'='	62	mg.kg-1
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	DOSE	'='	62	mg.kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	DOSE	'='	62	mg.kg-1
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Inhibition	'='	85	%
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Inhibition	'='	85	%
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Inhibition	'='	85	%
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	KD'	'='	0	M
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	IC50	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	-	-	-
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	IC50	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Ki	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	IC50	-	-	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	1	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	ED50	'='	0	mg.kg-1
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	Ki	'>'	10000	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	1	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	1	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	1	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	1000000	nM
P61169	BXGT011367	D(2) dopamine receptor	reviewed	-	Drd2	Ki	'>'	10000	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	ED50	'='	0	mg.kg-1
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	ED50	'='	0	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	ED50	'='	0	mg.kg-1
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Inhibition	'='	62	ug kg-1
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Inhibition	'='	62	ug kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Inhibition	'='	62	ug kg-1
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	436515	nM
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	660693	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	ED50	'='	0	mg.kg-1
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	ED50	'='	0	mg.kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ED50	'='	0	mg.kg-1
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	0	nM
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	602559	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	'='	1	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	-	-	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	-	-	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	IC50	-	-	-
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	Ki	-	-	-
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Ki	-	-	-
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	IC50	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Ki	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	IC50	-	-	-
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	IC50	-	-	-
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	IC50	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	IC50	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	Ki	-	-	-
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	Ki	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ki	'='	2	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	ED50	'='	22	mg.kg-1
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	ED50	'='	22	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	ED50	'='	22	mg.kg-1
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	IC50	'='	63200	nM
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	Activity	'='	0	pm/min/mg
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	EC50	'>'	5011	nM
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	EC50	'>'	5011	nM
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	IC50	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	Ki	'='	1423	nM
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	IC50	'='	380	nM
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	IC50	'='	2870	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Ki	'='	99	nM
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	Ki	-	-	-
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	IC50	-	-	-
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	IC50	'='	132	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Ki	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	EC50	'>'	5011	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	14	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	46	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Ki	'='	6	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Ki	'='	6	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	6	nM
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	1	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'>'	60	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	8	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Activity	'='	1	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Activity	'='	1	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Activity	'='	1	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Broncho selectivity	'='	0	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Broncho selectivity	'='	0	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	IC50	'='	28	nM
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	IC50	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	Ki	-	-	-
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	ED50	'='	0	mg.kg-1
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	Ki	-	-	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	253	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	39810	nM
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	Kd	'='	1	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	ED50	'='	0	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	63	%
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	EC50	'>'	5011	nM
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	EC50	'>'	5011	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	2	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	18000	nM
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	Inhibition	-	-	-
P23944	BXGT008930	Alpha-1D adrenergic receptor	reviewed	-	Adra1d	Inhibition	-	-	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	Inhibition	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ID50	'='	0	umol.kg-1
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	DR10	'>'	3	mg kg-1
P35368	BXGT009822	Alpha-1B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1B	DR10	'>'	3	mg kg-1
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	DR10	'>'	3	mg kg-1
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	DR10	'>'	3	mg kg-1
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	DR10	'>'	3	mg kg-1
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	DR10	'>'	3	mg kg-1
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	'='	90	nM
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Ki	-	-	-
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	Ki	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	IC50	-	-	-
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	IC50	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	Ki	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	IC50	-	-	-
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	Ki	-	-	-
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	IC50	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	Ki	-	-	-
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	Ki	-	-	-
P16662	BXGT008253	UDP-glucuronosyltransferase 2B7	reviewed	-	UGT2B7	Activity	'='	0	pm/min/mg
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	6	nM
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	IC50	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Heart rate	'='	7	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Heart rate	'='	7	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Log K'	'='	0	-
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	Kd	'>'	100000	nM
P35368	BXGT009822	Alpha-1B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1B	Kd	'>'	100000	nM
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	Kd	'>'	100000	nM
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	Kd	'>'	100000	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	Kd	'>'	100000	nM
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	Kd	'>'	100000	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Ki	'='	2	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Ki	'='	2	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	2	nM
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	Ki	-	-	-
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	IC50	-	-	-
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	Ki	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	Ki	-	-	-
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	Ki	-	-	-
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	IC50	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	IC50	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	2	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	2	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	2	nM
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	-	-	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	IC50	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	IC50	-	-	-
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Inhibition	'='	26	%
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Inhibition	'='	26	%
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	26	%
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio_Papp	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio_ATPase activity	'='	1	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	354813	nM
B9W4V6	BXGT002359	Aromatic peroxygenase	reviewed	-	APO1	Activity	'='	13	%
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	Inhibition	'='	55	%
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ID50	'='	0	mg.kg-1
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	39	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	IC50	'='	34	nM
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	IC50	'>'	5011	nM
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	IC50	'>'	10000	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	'='	18	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Selectivity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	573000	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	'='	1900	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	IC50	'>'	5011	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Selectivity	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	Ki	-	-	-
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	IC50	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	'='	0	nM
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	Ki	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Ki	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	Ki	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	Ki	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	Ki	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	IC50	'='	4	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	'='	4	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	'='	4	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Inhibition	-	-	-
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	IC50	'='	30	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	IC50	'='	30	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	IC50	'='	30	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	3	nM
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Ratio	'='	4	-
Q28998	BXGT013958	Beta-1 adrenergic receptor	reviewed	-	ADRB1	ED50	'='	0	mg.kg-1
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	IC50	-	-	-
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Kd	'='	2630	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	12	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	KD'	'='	0	M
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	44668	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	-	-	-
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	IC50	-	-	-
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	8	%
Q28997	BXGT013957	Beta-2 adrenergic receptor	reviewed	-	ADRB2	ED50	'='	0	mg.kg-1
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Inhibition	-	-	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	2	nM
P54833	BXGT011086	Beta-2 adrenergic receptor	reviewed	-	ADRB2	ID50	'='	0	mg.kg-1
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ratio	'='	0	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ratio	'='	0	-
P61169	BXGT011367	D(2) dopamine receptor	reviewed	-	Drd2	Ki	'='	12902	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Ratio	'='	12	-
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	1	nM
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	EC50	'>'	5011	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Inhibition	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	-	-	-
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	3	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'>'	5011	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Inhibition	'<'	10	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	496	nm/s
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	14	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	31	nM
B0FL73	BXGT001833	Beta-1 adrenergic receptor	unreviewed	-	ADRB1	Kd	'='	9	nM
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Affinity constant	'='	0	uM
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	IC50	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	IC50	-	-	-
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	IC50	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	IC50	'='	3065	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	'='	2	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	IC50	-	-	-
O60656	BXGT004889	UDP-glucuronosyltransferase 1-9	reviewed	-	UGT1A9	Activity	'='	40	pm/min/mg
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	Ki	'='	50	nM
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	Ki	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ki	'='	1	nM
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	IC50	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	ED50	'='	0	mg.kg-1
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	ED50	'='	0	mg.kg-1
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	IC50	'>'	5011	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	ED30	'>'	1000	ug kg-1
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	3162	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	AQ	'<'	0	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	IC50	'>'	5011	nM
P34969	BXGT009777	5-hydroxytryptamine receptor 7	reviewed	G-protein coupled receptor	HTR7	IC50	'>'	5011	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	'>'	5011	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	'>'	5011	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'>'	5011	nM
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	Ki	-	-	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	630957	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Inhibition	'<'	10	%
P36537	BXGT009924	UDP-glucuronosyltransferase 2B10	reviewed	-	UGT2B10	Activity	'='	0	pm/min/mg
O15296	BXGT004148	Arachidonate 15-lipoxygenase B	reviewed	Enzyme	ALOX15B	Potency	-	25118	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	0	nM
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	IC50	'>'	5011	nM
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	IC50	'>'	5011	nM
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	EC50	'>'	5011	nM
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	IC50	'>'	5011	nM
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	EC50	'>'	5011	nM
P34969	BXGT009777	5-hydroxytryptamine receptor 7	reviewed	G-protein coupled receptor	HTR7	EC50	'>'	5011	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'>'	10000	nM
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	IC50	-	-	-
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	Ki	-	-	-
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	reviewed	Ion channel	SCN5A	IC50	'='	2100	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ratio	'='	0	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ratio	'='	0	-
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	Ki	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	Ki	-	-	-
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	Ki	-	-	-
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio_Papp	'='	1	-
O94956	BXGT005343	Solute carrier organic anion transporter family member 2B1	reviewed	Transporter	SLCO2B1	Inhibition	'='	10	%
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	IC50	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	IC50	-	-	-
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	Ki	-	-	-
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	22387	nM
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	IC50	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	IC50	'>'	5011	nM
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	IC50	'>'	5011	nM
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	IC50	'>'	5011	nM
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	EC50	'>'	5011	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	'='	5011	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	-1	%
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Ki	-	-	-
P22909	BXGT008818	Alpha-2A adrenergic receptor	reviewed	-	Adra2a	Inhibition	-	-	-
P19328	BXGT008473	Alpha-2B adrenergic receptor	reviewed	-	Adra2b	Inhibition	-	-	-
P22086	BXGT008728	Alpha-2C adrenergic receptor	reviewed	-	Adra2c	Inhibition	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	507	nm/s
P14842	BXGT008059	5-hydroxytryptamine receptor 2A	reviewed	-	Htr2a	Ki	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Kd	'='	199	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	0	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	16360	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	213	nM
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	Ki	-	-	-
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	IC50	-	-	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	Ki	-	-	-
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	Ki	-	-	-
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	IC50	-	-	-
P06133	BXGT006414	UDP-glucuronosyltransferase 2B4	reviewed	-	UGT2B4	Activity	'='	0	pm/min/mg
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	IC50	-	-	-
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	Ki	-	-	-
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	IC50	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	Ki	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	IC50	'='	1466	nM
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	IC50	-	-	-
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	Ki	-	-	-
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	IC50	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	IC50	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	Ki	-	-	-
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	Ki	'='	202	nM
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	Ki	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	IC50	-	-	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	3	nM
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	IC50	'>'	5011	nM
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Kd	'='	162	nM
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	EC50	'>'	5011	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Kd	'='	0	nM
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	Ki	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	IC50	'>'	100000	nM
P23944	BXGT008930	Alpha-1D adrenergic receptor	reviewed	-	Adra1d	IC50	'>'	100000	nM
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	IC50	'>'	100000	nM
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	IC50	'>'	5011	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	'='	1	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Inhibition	'<'	10	%
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	Ki	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	IC50	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	Ki	-	-	-
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	IC50	-	-	-
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	IC50	-	-	-
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	IC50	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ki	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	IC50	-	-	-
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	Ki	-	-	-
Q8K4Z4	BXGT018404	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kd	'='	2	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Activity	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	IC50	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	IC50	-	-	-
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	IC50	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	-	-	-
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	Ki	-	-	-
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	-	-	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	IC50	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	IC50	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	Ki	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Ki	-	-	-
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	Ki	-	-	-
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	Ki	-	-	-
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	IC50	-	-	-
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	Ki	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	IC50	-	-	-
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Ki	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Inhibition	-	-	-
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	reviewed	G-protein coupled receptor	HTR1B	EC50	'>'	5011	nM
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	EC50	'>'	5011	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	EC50	'>'	5011	nM
P26255	BXGT009093	Beta-3 adrenergic receptor	reviewed	-	Adrb3	Inhibition	'='	100	%
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Inhibition	'='	100	%
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Inhibition	'='	100	%
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	Ki	-	-	-
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	IC50	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	Ki	-	-	-
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	IC50	-	-	-
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	IC50	-	-	-
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	IC50	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	IC50	'='	342	nM
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	Ki	-	-	-
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	IC50	'='	3981	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Kapp	'='	0	uM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	2828	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	EC50	'>'	5011	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Inhibition	'='	25	%
O15438	BXGT004168	Canalicular multispecific organic anion transporter 2	reviewed	Transporter	ABCC3	IC50	'='	133000	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	'='	3	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	'>'	10000	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Inhibition	'<'	10	%
P51589	BXGT010867	Cytochrome P450 2J2	reviewed	-	CYP2J2	IC50	'>'	50000	nM
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	IC50	'>'	5011	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	'='	50	nM
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	EC50	'>'	5011	nM
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	EC50	'>'	5011	nM
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	IC50	'>'	5011	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	'='	251	nM
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	IC50	'>'	5011	nM
P10608	BXGT007586	Beta-2 adrenergic receptor	reviewed	-	Adrb2	Kapp	'='	0	uM
O15439	BXGT004169	Multidrug resistance-associated protein 4	reviewed	Transporter	ABCC4	IC50	'='	133000	nM
O70127	BXGT005057	Bile salt export pump	reviewed	-	Abcb11	IC50	'>'	1000000	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Inhibition	-	-	-
Q06278	BXGT012869	Aldehyde oxidase	reviewed	Enzyme	AOX1	Fm	'='	0	-
Q14973	BXGT013515	Sodium/bile acid cotransporter	reviewed	Transporter	SLC10A1	IC50	'='	5500	nM
P30556	BXGT009441	Type-1 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR1	IC50	'>'	5011	nM
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	EC50	'>'	5011	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	'>'	10000	nM
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	IC50	'='	133000	nM
P15289	BXGT008102	Arylsulfatase A	reviewed	Enzyme	ARSA	Potency	-	2133	nM
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	14125	nM
P20813	BXGT008603	Cytochrome P450 2B6	reviewed	-	CYP2B6	Inhibition	'<'	10	%
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	135000	nM
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ki	'='	11	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	7	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'='	133000	nM
P18090	BXGT008380	Beta-1 adrenergic receptor	reviewed	-	Adrb1	Ki	'='	15	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00118	Nutmeg	Myristica fragrans	Herbs and Spices

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}