acompound

Showing entry for Verapamil

General Compound Information
BXGC Id	BXGC0044017
Compound Name	Verapamil
Structure
Formula	C27H38N2O4
InchiKey	SGTNSNPWRIOYBX-UHFFFAOYSA-N
SMILES	COc1ccc(cc1OC)CCN(CCCC(c1ccc(c(c1)OC)OC)(C(C)C)C#N)C
Inchi	InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
IUPAC	2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
Molecular Weight	454.28
Pubchem Id	2520
Chembl Id	CHEMBL6966

Targets of Information Source

DrugBank

DB00661

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	approved	inhibitor
Q00975	BXGT012558	Voltage-dependent N-type calcium channel subunit alpha-1B	reviewed	Ion channel	CACNA1B	approved	inhibitor
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	reviewed	Ion channel	CACNA1A	approved	inhibitor
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	reviewed	Ion channel	KCNJ11	approved	inhibitor
O43497	BXGT004596	Voltage-dependent T-type calcium channel subunit alpha-1G	reviewed	Ion channel	CACNA1G	approved	inhibitor
O95180	BXGT005358	Voltage-dependent T-type calcium channel subunit alpha-1H	reviewed	Ion channel	CACNA1H	approved	inhibitor
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	approved	inhibitor
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	approved	unknown
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	approved	antagonist
P35368	BXGT009822	Alpha-1B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1B	approved	antagonist
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	approved	antagonist

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

81939

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	>10000	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	40.3	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	66.7	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	38	-	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	10.6	-	-	-
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	-	3530	-	-
reviewed	BXGT008651	ATP-dependent translocase ABCB1	reviewed		Abcb1a	-	173000	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	53000	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	3100	-	-
reviewed	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	-	143	-	-
reviewed	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	-	141	-	-
reviewed	BXGT008115	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		CACNA1C	-	1000	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	-	39	-	-
reviewed	BXGT008211	Translocator protein	reviewed		Tspo	-	1.4	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	120
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	150	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	3100
reviewed	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	-	145	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	1041
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	20000
reviewed	BXGT021119	Chloroquine resistance transporter	reviewed		CRT	-	33000	-	-
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	13400	-	-	-
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	13200	-	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	9800	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	500	-	-
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	-	6800	-	-
reviewed	BXGT007592	Cytochrome P450 2C8	reviewed		CYP2C8	17500	-	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	-	-	37300
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	-	-	-	27800
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	-	79	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	-	398	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	-	1585	-	-
reviewed	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed		Cacna1c	-	481	-	-
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	-	3500	-	-
reviewed	BXGT013478	Sodium channel protein type 5 subunit alpha	reviewed	Ion channel	SCN5A	-	41500	-	-
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	100	-	-
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	23500	-	-
reviewed	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	-	32000	-	-
reviewed	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	-	64000	-	-
reviewed	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	-	>600000	-	-
reviewed	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	52000	-	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	38	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	385
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	503
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	446
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	-	245
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	164	-	-
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	790	-	-
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	940	-	-
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	47000	-	-
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	50000	-	-
reviewed	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C (Fragment)	reviewed		CACNA1C	-	600	-	-
reviewed	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	-	24000	-	-
reviewed	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	-	17600	-	-
reviewed	BXGT007595	Cytochrome P450 2D6	reviewed		CYP2D6	-	>30000	-	-
reviewed	BXGT009707	Cytochrome P450 2C19	reviewed		CYP2C19	-	>30000	-	-
reviewed	BXGT007738	Cytochrome P450 2C9	reviewed		CYP2C9	-	>30000	-	-
reviewed	BXGT007592	Cytochrome P450 2C8	reviewed		CYP2C8	-	>30000	-	-
reviewed	BXGT009707	Cytochrome P450 2C19	reviewed		CYP2C19	-	21800	-	-
reviewed	BXGT007738	Cytochrome P450 2C9	reviewed		CYP2C9	-	>50000	-	-
reviewed	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	-	12000	-	-
reviewed	BXGT010867	Cytochrome P450 2J2	reviewed		CYP2J2	-	22000	-	-
reviewed	BXGT007595	Cytochrome P450 2D6	reviewed		CYP2D6	-	43300	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	65600	-	-
reviewed	BXGT009838	Sodium channel protein type 1 subunit alpha	reviewed	Ion channel	SCN1A	-	3300	-	-
reviewed	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	-	141.25	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	4780	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	2210	-	-

CHEMBL

CHEMBL6966

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Emax	'='	98	%
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Emax	'='	98	%
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Emax	'='	98	%
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	AUC	'='	0	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	AUC	'='	0	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	AUC	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	6	-
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	MEC	'='	50	ug ml-1
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	141	nM
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	Ratio	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	Ki	-	-	-
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	Ki	-	-	-
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	IC50	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Ki	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Ki	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Ki	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	IC50	'='	186	nM
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	Ki	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	IC50	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Ki	-	-	-
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	53000	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	35900	-
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	Ki	-	-	-
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	IC50	-	-	-
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	IC50	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	Ki	-	-	-
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Ki	-	-	-
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Ki	-	-	-
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	Ki	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	Ki	'='	155	nM
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	Ki	-	-	-
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	IC50	-	-	-
Q28998	BXGT013958	Beta-1 adrenergic receptor	reviewed	-	ADRB1	ED50	'>'	3	mg.kg-1
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Km	'='	24000	nM
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Ratio	'='	1	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	3	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	3	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	3	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	42000	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	'>'	30000	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	'>'	30000	nM
Q9Z0E8	BXGT022397	Solute carrier family 22 member 5	reviewed	-	Slc22a5	Activity	'='	1	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	4700	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Vmax	'='	65	uM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	164	nM
O60840	BXGT004901	Voltage-dependent L-type calcium channel subunit alpha-1F	reviewed	Ion channel	CACNA1F	IC50	'='	200	nM
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	Ion channel	CACNA1D	IC50	'='	200	nM
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	Ion channel	CACNA1S	IC50	'='	200	nM
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	200	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	65600	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	446	nM
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	IC50	-	-	-
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	Ki	-	-	-
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	Ki	-	-	-
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	Ki	-	-	-
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	IC50	-	-	-
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	IC50	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	IC50	-	-	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	IC50	'='	1698	nM
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	17782	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	143	nM
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	Ki	-	-	-
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	Ki	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	IC50	-	-	-
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	IC50	-	-	-
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	Ki	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	IC50	'='	442	nM
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	Ki	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	IC50	'='	3020	nM
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	Ki	-	-	-
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Ratio	'='	11	-
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	Inhibition	'='	86	%
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	FICI	'>'	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	IC50	-	-	-
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	IC50	-	-	-
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	46100	-
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	IC50	'='	30000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	0	-
P20813	BXGT008603	Cytochrome P450 2B6	reviewed	-	CYP2B6	Inhibition	'='	10	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FICI	'<'	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	46	-
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	100	nM
P43245	BXGT010370	ATP-dependent translocase ABCB1	reviewed	-	Abcb1	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio_Papp	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	13	-
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	FC	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	17	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	Ki	'='	940	nM
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	Ki	-	-	-
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	Ki	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Ki	-	-	-
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	Ki	'='	2547	nM
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	IC50	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	IC50	'='	297	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	1	-
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	Inhibition	-	-	-
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	FC	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	INH	'='	1	uM
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	Ki	'='	17500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	15100	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	880	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	27	-
P15381	BXGT008115	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	1000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	0	-
Q6PSM0	BXGT016483	Multidrug resistance protein 1a	unreviewed	-	Mdr1a	Activity	-	-	-
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	3100	nM
O76082	BXGT005175	Solute carrier family 22 member 5	reviewed	Transporter	SLC22A5	Activity	'='	2	%
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ratio IC50	'='	7	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Activity	'='	2	uM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	17	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	1584	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	1584	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	1584	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ki	'='	13200	nM
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	212	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	1750	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	5	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	8440	nM
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	Ki	'='	2900	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	69	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	1253	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	3100	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	188	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	9800	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ki	'='	13400	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Inhibition	'='	50	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'>'	32	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	591	nm/s
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'='	79100	nM
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	MIC	'='	2	ug.mL-1
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	5	-
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	IC50	-	-	-
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	IC50	-	-	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	FC	'='	5	-
P46720	BXGT010535	Solute carrier organic anion transporter family member 1A1	reviewed	-	Slco1a1	Activity	'='	3	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Km	'='	2000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	2210	nM
Q28997	BXGT013957	Beta-2 adrenergic receptor	reviewed	-	ADRB2	ED50	'>'	3	mg.kg-1
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	reviewed	Ion channel	SCN3A	IC50	'='	3300	nM
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	reviewed	Ion channel	SCN2A	IC50	'='	3300	nM
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	reviewed	Ion channel	SCN1A	IC50	'='	3300	nM
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	Ki	-	-	-
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Alpha max	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	ED50	'='	3	uM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	95	%
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	39810	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	39810	nM
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Kd	'='	645654	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Km	'='	4060	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	28	%
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	Ratio	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	451	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	101	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Activity	-	-	-
P51589	BXGT010867	Cytochrome P450 2J2	reviewed	-	CYP2J2	Activity	'='	69	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	89	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	20000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	35	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	10	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Ki	'='	58	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	6606	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	398	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	398	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	398	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	0	-
O35913	BXGT004540	Solute carrier organic anion transporter family member 1A4	reviewed	-	Slco1a4	Activity	'='	4	%
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	Ki	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Ki	-	-	-
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	Ki	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	IC50	'='	165	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FICI	'<'	0	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	-	-	-
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	Ki	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	IC50	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	IC50	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	IC50	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	Ki	'='	63	nM
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	IC50	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ki	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	-	-	-
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	Ki	-	-	-
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	IC50	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	481	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	481	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	481	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Inhibition	-	-	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Inhibition	-	-	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Inhibition	-	-	-
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	IC50	'='	64000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	445	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	4570	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	20	-
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	144	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	2100	nM
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	IC50	'='	10000	nM
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Ratio	'='	6	-
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Ratio	'='	6	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Log K'	'='	0	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Ki	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	Ki	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	-	-	-
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	Ki	-	-	-
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	Ki	-	-	-
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	IC50	-	-	-
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	IC50	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	-	-	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	-	-	-
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	2110	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	2500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	30	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	2147483647	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Emax	'='	99	%
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Emax	'='	99	%
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Emax	'='	99	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	29	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	17	-
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	Ki	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	18900	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	28900	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ratio	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Ki	'='	1	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Ki	'='	1	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Ki	'='	1	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	3100	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibitory ratio	'='	7	-
P0A0J7	BXGT006970	Quinolone resistance protein NorA	reviewed	-	norA	Inhibition	-	-	-
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	150	nM
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	524807	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	42	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Inhibition	'<'	10	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	6	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	52	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	3	-
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	29092	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	17	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	33	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	154	-
P06795	BXGT006507	ATP-dependent translocase ABCB1	reviewed	-	Abcb1b	Activity	'='	7	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	129	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'='	12000	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'>'	50000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	28	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	26608	nM
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	Ki	-	-	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	6300	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	7	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	1	uM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	5800	nM
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	98	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	63	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	439	-
Q96QA9	BXGT019717	Multidrug resistance associated protein	unreviewed	-	MRP3	Activity	'='	32	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	13	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ratio IC50	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	400	nM
P16257	BXGT008211	Translocator protein	reviewed	-	Tspo	IC50	'='	1	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ratio IC50	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	8	-
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Log B/F	'='	0	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	IC50	'='	6800	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P04156	BXGT006156	Major prion protein	reviewed	-	PRNP	RUmax	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	446500	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	600	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	'='	10	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Inhibition	-	-	-
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Ki	-	-	-
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	IC50	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Ki	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	IC50	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	Ki	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	IC50	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	Ki	-	-	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	IC50	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	IC50	-	-	-
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	Ki	-	-	-
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	IC50	'='	240	nM
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	IC50	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	IC50	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	Ki	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	-	-	-
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	IC50	-	-	-
P46721	BXGT010536	Solute carrier organic anion transporter family member 1A2	reviewed	Transporter	SLCO1A2	Inhibition	'='	100	%
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	IC50	'='	33000	nM
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	IC50	'='	2590	nM
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	39810	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	740	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	5200	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	14000	nM
Q5T3U5	BXGT015846	Multidrug resistance-associated protein 7	reviewed	Transporter	ABCC10	Activity	'='	62	%
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	Inhibition	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	17	-
O94956	BXGT005343	Solute carrier organic anion transporter family member 2B1	reviewed	Transporter	SLCO2B1	Inhibition	'='	-62	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Papp	'='	687	nm/s
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	FC	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	251	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	6	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	K	'='	0	/s
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	Ki	-	-	-
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	Ki	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	-	-	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	-	-	-
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	Ki	-	-	-
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	Ki	-	-	-
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	Ki	-	-	-
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	Ki	-	-	-
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	IC50	-	-	-
P06795	BXGT006507	ATP-dependent translocase ABCB1	reviewed	-	Abcb1b	Activity	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	53000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	1041	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Binding site fraction	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	9	-
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	-	-	-
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	IC50	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	IC50	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	IC50	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	Ki	-	-	-
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	IC50	-	-	-
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	Ki	-	-	-
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	Ki	-	-	-
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	IC50	-	-	-
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	IC50	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	IC50	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	Ki	'='	126	nM
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	21	nM/mg*min
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	1480	nM
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	IC50	-	-	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	Ki	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Ki	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	9	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'='	4700	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	1190	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	67	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	300	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	158	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	5	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	8	-
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	IC50	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Ki	-	-	-
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Ki	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ki	-	-	-
Q9N623	BXGT021119	Chloroquine resistance transporter	reviewed	-	CRT	Inhibition	'='	74	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	33498	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	5754	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	5	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RFU	'='	98700	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	12000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	5	-
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	50000	nM
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	4	-
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'='	178900	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	4780	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	1	-
O15439	BXGT004169	Multidrug resistance-associated protein 4	reviewed	Transporter	ABCC4	Activity	'='	61	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	60	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	6500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	1600	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	17	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	7	-
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	reviewed	Ion channel	SCN3A	Inhibition	'='	74	%
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	reviewed	Ion channel	SCN2A	Inhibition	'='	74	%
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	reviewed	Ion channel	SCN1A	Inhibition	'='	74	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	2	-
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	Activity	'='	56	%
Q9R141	BXGT021411	Solute carrier family 22 member 4	reviewed	-	Slc22a4	Activity	'='	20	%
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	IC50	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	IC50	-	-	-
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	IC50	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	7	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	120	nM
O76082	BXGT005175	Solute carrier family 22 member 5	reviewed	Transporter	SLC22A5	Activity	-	-	-
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	EC50	'='	37300	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	9466	nM
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	Kinact	'='	0	min-1
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	IC50	'='	9660	nM
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	IC50	'>'	200000	nM
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	Ki	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	Ki	-	-	-
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	Ki	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	Ki	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	Ki	-	-	-
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	IC50	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	IC50	-	-	-
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	IC50	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	'='	1726	nM
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	Ki	-	-	-
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	Ki	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	IC50	'='	2092	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Fluorescence intensity	'='	11	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Activity	-	-	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Ratio	'='	1	-
P06199	BXGT006420	Muscarinic acetylcholine receptor M2	reviewed	-	CHRM2	EC50	'='	30974	nM
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	IC50	'='	6800	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	98	%
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	398	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	10	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	1	-
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	IC50	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	Ki	-	-	-
P06795	BXGT006507	ATP-dependent translocase ABCB1	reviewed	-	Abcb1b	IC50	'='	2000	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Inhibition	'='	51	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	385	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	39	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	940	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Alpha max	'='	0	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ki	'='	3000	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	1800	nM
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	reviewed	Transporter	ABCB4	Activity	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	21	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	245	nM
O15438	BXGT004168	Canalicular multispecific organic anion transporter 2	reviewed	Transporter	ABCC3	IC50	'='	133000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	22	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	129	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	25	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	10	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	IC50	-	-	-
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	IC50	-	-	-
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	IC50	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	Ki	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	IC50	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	IC50	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	IC50	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	IC50	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	Ki	'='	847	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	Ki	'='	217	nM
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	IC50	-	-	-
Q9Z0E8	BXGT022397	Solute carrier family 22 member 5	reviewed	-	Slc22a5	Activity	-	-	-
Q9H015	BXGT020432	Solute carrier family 22 member 4	reviewed	Transporter	SLC22A4	Activity	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	pIC50	-	-	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	pIC50	-	-	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	pIC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	18000	nM
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	Kd	'='	1000	nM
P35368	BXGT009822	Alpha-1B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1B	Kd	'='	1000	nM
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	Kd	'='	1000	nM
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	Kd	'='	1000	nM
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	Kd	'='	1000	nM
P35348	BXGT009814	Alpha-1A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1A	Kd	'='	1000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	6	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	1700	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Inhibition	'<'	10	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	20542	nM
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	FC	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	5	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	6	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	156	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio_ATPase activity	'='	7	-
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	Inhibition	'<'	10	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	20	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	38	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	% maximum response	'='	56	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	RLU	'='	4	-
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	Ki	'='	127	nM
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	IC50	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	-	-	-
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	Ki	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	4200	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	198	-
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	35481	nM
P43220	BXGT010367	Glucagon-like peptide 1 receptor	reviewed	G-protein coupled receptor	GLP1R	Potency	-	14125	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
Q9H015	BXGT020432	Solute carrier family 22 member 4	reviewed	Transporter	SLC22A4	Activity	'='	8	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	10730	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P22001	BXGT008716	Potassium voltage-gated channel subfamily A member 3	reviewed	Ion channel	KCNA3	IC50	'='	8000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	20	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	23	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	MIC	'='	8000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Flu intensity	'='	36	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	575	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	5420	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'='	76032	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	FC	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	18	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	8	-
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	40	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	60	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	27	-
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	reviewed	Ion channel	SCN5A	IC50	'='	41500	nM
P51589	BXGT010867	Cytochrome P450 2J2	reviewed	-	CYP2J2	IC50	'='	22000	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Emax	'='	99	%
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Emax	'='	99	%
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Emax	'='	99	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	76	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P03522	BXGT026128	Glycoprotein	reviewed	-	G	IC50	'>'	200000	nM
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	24000	nM
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	47000	nM
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	IC50	-	-	-
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	IC50	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	-	-	-
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	IC50	-	-	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	IC50	-	-	-
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	IC50	-	-	-
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	IC50	-	-	-
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	-	-	-
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	Ki	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	IC50	-	-	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Ki	-	-	-
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	IC50	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	2611	-
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	-	-	-
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	IC50	-	-	-
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	IC50	-	-	-
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	IC50	'='	579	nM
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	IC50	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	Ki	-	-	-
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	Ki	-	-	-
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	Ki	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	IC50	-	-	-
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	Ki	-	-	-
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	IC50	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Ki	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	IC50	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	Ki	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	Ki	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	Ki	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	Ki	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	IC50	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	Ki	-	-	-
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	IC50	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	IC50	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	IC50	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	Ki	-	-	-
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	Ki	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	Ki	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Emax	'='	100	%
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Emax	'='	100	%
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Emax	'='	100	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
Q99700	BXGT019949	Ataxin-2	reviewed	Nucleic acid binding	ATXN2	Potency	-	28183	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	22387	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	27	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	17550	nM
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	'='	23500	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	790	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	17	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	IC50	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	IC50	-	-	-
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	IC50	-	-	-
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	IC50	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	IC50	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	Ki	'='	105	nM
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'>'	50000	nM
O15439	BXGT004169	Multidrug resistance-associated protein 4	reviewed	Transporter	ABCC4	Activity	'='	53	%
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	'>'	50000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	224000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
P21447	BXGT008651	ATP-dependent translocase ABCB1	reviewed	-	Abcb1a	Km	'='	10000	nM
P56817	BXGT011200	Beta-secretase 1	reviewed	Enzyme	BACE1	Kd	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	79	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	79	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	79	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	4	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	IC50	'='	3500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	30	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	IC50	'='	32000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	129	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	'>'	30000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	12	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Inhibition	'<'	10	%
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	IC50	'='	133000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	EC50	'='	503	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Ki	'='	52000	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Emax	-	-	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Emax	-	-	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Emax	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	29	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	'='	61	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	12	-
P25779	BXGT009067	Cruzipain	reviewed	-		Inhibition	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	'='	21800	nM
O75387	BXGT005122	Large neutral amino acids transporter small subunit 3	reviewed	Transporter	SLC43A1	Inhibition	'='	82	%
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	Activity	'<'	2000	FU
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	IC50	'>'	600000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	5	-
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	1500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	4	-
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	-9	%
P10632	BXGT007592	Cytochrome P450 2C8	reviewed	-	CYP2C8	IC50	'>'	30000	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'>'	30000	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Inhibition	'<'	10	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	38200	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	13	-
P51589	BXGT010867	Cytochrome P450 2J2	reviewed	-	CYP2J2	Activity	'='	1	%
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'='	133000	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	31280	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	1	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	EC50	'='	1925	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	EC50	'='	27800	nM
O15439	BXGT004169	Multidrug resistance-associated protein 4	reviewed	Transporter	ABCC4	IC50	'='	133000	nM
O70127	BXGT005057	Bile salt export pump	reviewed	-	Abcb11	Ki	'='	92500	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	19	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	2	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	4	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Activity	'='	1078	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'='	17600	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	'='	43300	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	135000	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Inhibition	'='	100	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	20	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	1	-
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	FC	'='	2	-
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	FICI	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	6	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	Inhibition	'='	80	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	3	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	4	-
P22460	BXGT008774	Potassium voltage-gated channel subfamily A member 5	reviewed	Ion channel	KCNA5	Inhibition	-	-	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	8	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	FC	'='	3	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	FC	'='	1	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	0	-
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio IC50	'='	15	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'='	8193	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Ratio	'='	9	-
A0R5K5	BXGT026094	Multidrug efflux pump LfrA	reviewed	-	lfrA	FICI	'='	1	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00139	Pepper (Spice)	Piper nigrum	Herbs and Spices

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}