Showing entry for Acid-sensing ion channel 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016051
Protein NameAcid-sensing ion channel 2
Uniport IdQ62962
GeneAsic2
Gene Id25364
DomainASC
Pfam PF00858  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006812 cation transport
Biological Process GO:0071468 cellular response to acidic pH
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0050974 detection of mechanical stimulus involved in sensory perception
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0007602 phototransduction
Biological Process GO:2001259 positive regulation of cation channel activity
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0035418 protein localization to synapse
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
Biological Process GO:0019229 regulation of vasoconstriction
Biological Process GO:0010447 response to acidic pH
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0050915 sensory perception of sour taste
Biological Process GO:0006814 sodium ion transport
molecular function GO:0005261 cation channel activity
molecular function GO:0005216 ion channel activity
molecular function GO:0022839 ion gated channel activity
molecular function GO:0015280 ligand-gated sodium channel activity
molecular function GO:0005248 voltage-gated sodium channel activity
cellular component GO:0043197 dendritic spine
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000663 Papain 206.28
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0049738 Dexibuprofen 206.13
BXGC0052021 (R)-Ibuprophen 206.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein