Showing entry for Rho-related GTP-binding protein RhoU



                       
General Target Information
BXGT IdBXGT016991
Protein NameRho-related GTP-binding protein RhoU
Uniport IdQ7L0Q8
GeneRHOU
Gene Id58480
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0032488 Cdc42 protein signal transduction
Biological Process GO:0016477 cell migration
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0006897 endocytosis
Biological Process GO:0000082 G1/S transition of mitotic cell cycle
Biological Process GO:1903955 positive regulation of protein targeting to mitochondrion
Biological Process GO:0016601 Rac protein signal transduction
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0051056 regulation of small GTPase mediated signal transduction
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0046872 metal ion binding
cellular component GO:0042995 cell projection
cellular component GO:0005829 cytosol
cellular component GO:0005925 focal adhesion
cellular component GO:0000139 Golgi membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0002102 podosome
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194840 Rho GTPase cycle
R-HSA-449147 Signaling by Interleukins
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0153567 BXGD003665 Uterine Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0349782 BXGD007954 Ischemic cardiomyopathy Cardiovascular Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0855095 BXGD011071 Small Lymphocytic Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510475 BXGD013171 Diverticulosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein