Showing entry for Cardiomyopathy, Familial Idiopathic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013086
Disease NameCardiomyopathy, Familial Idiopathic
Disease CUI IdC1449563
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00305 BXGT003907 Voltage-dependent L-type calcium channel subunit beta-4 785 reviewed Ion channel
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00408 BXGT003916 cGMP-dependent 3',5'-cyclic phosphodiesterase 5138 reviewed
O00512 BXGT003933 B-cell CLL/lymphoma 9 protein 607 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14558 BXGT004070 Heat shock protein beta-6 126393 reviewed
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15247 BXGT004142 Chloride intracellular channel protein 2 1193 reviewed Ion channel
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O43451 BXGT004594 Maltase-glucoamylase, intestinal 8972 reviewed Enzyme
O60240 BXGT004860 Perilipin-1 5346 reviewed
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O75112 BXGT005099 LIM domain-binding protein 3 11155 reviewed Cellular structure
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O76082 BXGT005175 Solute carrier family 22 member 5 6584 reviewed Transporter
O94760 BXGT005328 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 23576 reviewed Enzyme
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 9133 reviewed Enzyme modulator
O95347 BXGT005374 Structural maintenance of chromosomes protein 2 10592 reviewed
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
O95865 BXGT005404 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 23564 reviewed Enzyme
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05141 BXGT006325 ADP/ATP translocase 2 292 reviewed Transporter
P05165 BXGT006334 Propionyl-CoA carboxylase alpha chain, mitochondrial 5095 reviewed Enzyme
P05166 BXGT006335 Propionyl-CoA carboxylase beta chain, mitochondrial 5096 reviewed Enzyme
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07437 BXGT006624 Tubulin beta chain 203068 reviewed Cellular structure
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P08670 BXGT006810 Vimentin 7431 reviewed
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10909 BXGT007630 Clusterin 1191 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12235 BXGT007774 ADP/ATP translocase 1 291 reviewed Transporter
P12236 BXGT007775 ADP/ATP translocase 3 293 reviewed Transporter
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P13727 BXGT007951 Bone marrow proteoglycan 5553 reviewed Enzyme modulator
P13866 BXGT007963 Sodium/glucose cotransporter 1 6523 reviewed Transporter
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P15941 BXGT008176 Mucin-1 4582 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18206 BXGT008389 Vinculin 7414 reviewed
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18846 BXGT008430 Cyclic AMP-dependent transcription factor ATF-1 466 reviewed
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21583 BXGT008667 Kit ligand 4254 reviewed
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22033 BXGT008721 Methylmalonyl-CoA mutase, mitochondrial 4594 reviewed Enzyme
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25713 BXGT009062 Metallothionein-3 4504 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28347 BXGT009257 Transcriptional enhancer factor TEF-1 7003 reviewed Transcription factor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P29034 BXGT009309 Protein S100-A2 6273 reviewed Calcium-binding protein
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P30536 BXGT009435 Translocator protein 706 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32929 BXGT009682 Cystathionine gamma-lyase 1491 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P34949 BXGT009775 Mannose-6-phosphate isomerase 4351 reviewed Enzyme
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35414 BXGT009829 Apelin receptor 187 reviewed G-protein coupled receptor
P35590 BXGT009854 Tyrosine-protein kinase receptor Tie-1 7075 reviewed Kinase
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36871 BXGT009936 Phosphoglucomutase-1 5236 reviewed
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P37059 BXGT009957 Estradiol 17-beta-dehydrogenase 2 3294 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40925 BXGT010206 Malate dehydrogenase, cytoplasmic 4190 reviewed Enzyme
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48507 BXGT010636 Glutamate--cysteine ligase regulatory subunit 2730 reviewed Enzyme
P48544 BXGT010641 G protein-activated inward rectifier potassium channel 4 3762 reviewed Ion channel
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P50583 BXGT010813 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] 318 reviewed Enzyme
P51114 BXGT010832 Fragile X mental retardation syndrome-related protein 1 8087 reviewed Nucleic acid binding
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51884 BXGT010903 Lumican 4060 reviewed
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 4751 reviewed Kinase
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles 7134 reviewed Calcium-binding protein
P67775 BXGT011563 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 5515 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q04446 BXGT012764 1,4-alpha-glucan-branching enzyme 2632 reviewed Enzyme
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q08289 BXGT012979 Voltage-dependent L-type calcium channel subunit beta-2 783 reviewed Ion channel
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q12959 BXGT013283 Disks large homolog 1 1739 reviewed Receptor
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13105 BXGT013311 Zinc finger and BTB domain-containing protein 17 7709 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14123 BXGT013445 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 5137 reviewed
Q14126 BXGT013446 Desmoglein-2 1829 reviewed Cell adhesion
Q14315 BXGT013460 Filamin-C 2318 reviewed
Q14392 BXGT013465 Transforming growth factor beta activator LRRC32 2615 reviewed Receptor
Q14432 BXGT013469 cGMP-inhibited 3',5'-cyclic phosphodiesterase A 5139 reviewed
Q14498 BXGT013475 RNA-binding protein 39 9584 reviewed
Q14500 BXGT013477 ATP-sensitive inward rectifier potassium channel 12 3768 reviewed Ion channel
Q14524 BXGT013478 Sodium channel protein type 5 subunit alpha 6331 reviewed Ion channel
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15139 BXGT013546 Serine/threonine-protein kinase D1 5587 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle 4638 reviewed Kinase
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15842 BXGT013607 ATP-sensitive inward rectifier potassium channel 8 3764 reviewed Ion channel
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15942 BXGT013613 Zyxin 7791 reviewed Enzyme modulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q32MK0 BXGT014323 Myosin light chain kinase 3 91807 reviewed Kinase
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q59H18 BXGT015278 Serine/threonine-protein kinase TNNI3K 51086 reviewed
Q5VST9 BXGT015886 Obscurin 84033 reviewed Kinase
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q7L0Q8 BXGT016991 Rho-related GTP-binding protein RhoU 58480 reviewed Enzyme modulator
Q7Z7D3 BXGT017262 V-set domain-containing T-cell activation inhibitor 1 79679 reviewed Enzyme modulator
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q8N3J5 BXGT018506 Protein phosphatase 1K, mitochondrial 152926 reviewed Enzyme
Q8NB16 BXGT018535 Mixed lineage kinase domain-like protein 197259 reviewed Kinase
Q8TEK3 BXGT018822 Histone-lysine N-methyltransferase, H3 lysine-79 specific 84444 reviewed Epigenetic regulator
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96DB2 BXGT019639 Histone deacetylase 11 79885 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96F46 BXGT019656 Interleukin-17 receptor A 23765 reviewed
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q96RT1 BXGT019736 Erbin 55914 reviewed
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q99959 BXGT019977 Plakophilin-2 5318 reviewed Cellular structure
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZ11 BXGT020193 Disintegrin and metalloproteinase domain-containing protein 33 80332 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NVS9 BXGT021228 Pyridoxine-5'-phosphate oxidase 55163 reviewed Enzyme
Q9P0Z9 BXGT021294 Peroxisomal sarcosine oxidase 51268 reviewed Enzyme
Q9P2K8 BXGT021302 eIF-2-alpha kinase GCN2 440275 reviewed
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UIK4 BXGT021720 Death-associated protein kinase 2 23604 reviewed Kinase
Q9UQ80 BXGT021806 Proliferation-associated protein 2G4 5036 reviewed
Q9Y2K7 BXGT022239 Lysine-specific demethylase 2A 22992 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y4U1 BXGT022285 Methylmalonic aciduria and homocystinuria type C protein 25974 reviewed
P35232 BXGT022663 Prohibitin 5245 reviewed
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
O60939 BXGT023048 Sodium channel subunit beta-2 6327 reviewed Ion channel
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
Q9BYE2 BXGT024631 Transmembrane protease serine 13 84000 reviewed Enzyme
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
P38646 BXGT024954 Stress-70 protein, mitochondrial 3313 reviewed
Q7L8A9 BXGT025010 Tubulinyl-Tyr carboxypeptidase 1 22846 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9NRR4 BXGT025788 Ribonuclease 3 29102 reviewed Enzyme
O14917 BXGT025818 Protocadherin-17 27253 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease