adisease

Showing entry for Kidney Neoplasm

General Disease Information
BXGD Id	BXGD001573
Disease Name	Kidney Neoplasm
Disease CUI Id	C0022665
MeSH Codes	C04 C13 C12
Disease Class Name	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000119 HP:0002664
Human Phenotype Ontology Term	Abnormality of the genitourinary system; Neoplasm
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00194	BXGT003892	Ras-related protein Rab-27B	5874	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14727	BXGT004084	Apoptotic protease-activating factor 1	317	reviewed
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O15169	BXGT004134	Axin-1	8312	reviewed
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	11200	reviewed	Kinase
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05141	BXGT006325	ADP/ATP translocase 2	292	reviewed	Transporter
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05937	BXGT006396	Calbindin	793	reviewed	Calcium-binding protein
P06276	BXGT006430	Cholinesterase	590	reviewed
P06746	BXGT006496	DNA polymerase beta	5423	reviewed	Enzyme
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08670	BXGT006810	Vimentin	7431	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12830	BXGT007852	Cadherin-1	999	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19525	BXGT008492	Interferon-induced, double-stranded RNA-activated protein kinase	5610	reviewed	Kinase
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22392	BXGT008762	Nucleoside diphosphate kinase B	654364	reviewed	Kinase
P23246	BXGT008840	Splicing factor, proline- and glutamine-rich	6421	reviewed	Nucleic acid binding
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25325	BXGT009038	3-mercaptopyruvate sulfurtransferase	4357	reviewed	Enzyme
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30530	BXGT009431	Tyrosine-protein kinase receptor UFO	558	reviewed	Kinase
P30533	BXGT009434	Alpha-2-macroglobulin receptor-associated protein	4043	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32929	BXGT009682	Cystathionine gamma-lyase	1491	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35243	BXGT009803	Recoverin	5957	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P43487	BXGT010393	Ran-specific GTPase-activating protein	5902	reviewed	Enzyme modulator
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49674	BXGT010725	Casein kinase I isoform epsilon	1454	reviewed
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62753	BXGT011454	40S ribosomal protein S6	6194	reviewed	Nucleic acid binding
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	2564	reviewed	Ion channel
P81172	BXGT011935	Hepcidin	57817	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q07011	BXGT012912	Tumor necrosis factor receptor superfamily member 9	3604	reviewed
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q13467	BXGT013358	Frizzled-5	7855	reviewed	G-protein coupled receptor
Q13541	BXGT013371	Eukaryotic translation initiation factor 4E-binding protein 1	1978	reviewed	Nucleic acid binding
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14527	BXGT013479	Helicase-like transcription factor	6596	reviewed
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16773	BXGT013667	Kynurenine--oxoglutarate transaminase 1	883	reviewed	Enzyme
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q7L0Q8	BXGT016991	Rho-related GTP-binding protein RhoU	58480	reviewed	Enzyme modulator
Q8TDU6	BXGT018814	G-protein coupled bile acid receptor 1	151306	reviewed	G-protein coupled receptor
Q8TF65	BXGT018825	PDZ domain-containing protein GIPC2	54810	reviewed	Enzyme
Q95460	BXGT019580	Major histocompatibility complex class I-related gene protein	3140	reviewed
Q96BI3	BXGT019623	Gamma-secretase subunit APH-1A	51107	reviewed	Enzyme modulator
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96JA1	BXGT019681	Leucine-rich repeats and immunoglobulin-like domains protein 1	26018	reviewed	Receptor
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H7Z6	BXGT020493	Histone acetyltransferase KAT8	84148	reviewed
Q9HD42	BXGT020543	Charged multivesicular body protein 1a	5119	reviewed
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9UKV5	BXGT021751	E3 ubiquitin-protein ligase AMFR	267	reviewed
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y646	BXGT022317	Carboxypeptidase Q	10404	reviewed	Enzyme
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P35240	BXGT022927	Merlin	4771	reviewed
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
P21926	BXGT024578	CD9 antigen	928	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q92729	BXGT025605	Receptor-type tyrosine-protein phosphatase U	10076	reviewed	Enzyme
P19532	BXGT026110	Transcription factor E3	7030	reviewed
Q08477	BXGT026164	Docosahexaenoic acid omega-hydroxylase CYP4F3	4051	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}